Single-blinded, Double-arm, Controlled, Randomized, Multicentre Clinical Trial to Evaluate the Impact of Pharmacogenetic-guided Treatment in Patients With Insufficiently Controlled Type 2 Diabetes

The goal of this clinical trial is to assess the efficacy of a pharmacogenetics-guided treatment, compared to standard optimized treatment, in patients with inadequately controlled type 2 diabetes. The main questions it aims to answer are:
* Is the disease better controlled when the treatment prescribed is based on the participant's pharmacogenetic profile?
* What medical problems do participants experience while taking the treatment?
Participants will:
* Take the treatment described according to the Summary of Product Characteristics (SmPC).
* Visit the clinic once every 12 weeks for checkups and tests.
* Keep a diary of their symptoms to inform the Investigator.

开始日期2025-04-01

申办/合作机构-

100 项与维格列汀相关的临床结果

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100 项与维格列汀相关的转化医学

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100 项与维格列汀相关的专利（医药）

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1,606

项与维格列汀相关的文献（医药）

2026-02-01·CPT-Pharmacometrics & Systems Pharmacology

Preclinical Modeling and Simulation to Explore the Tissue/Plasma Exposure and Pharmacodynamic Effect of Vildagliptin in Diabetes Treatment

Article

作者: Bruna Bernar Dias ; Laura Ben Olivo ; Bibiana Verlindo de Araújo

ABSTRACT:

Vildagliptin (VDG) is a dipeptidyl‐peptidase‐4 (DPP‐4) inhibitor used for type 2 diabetes (T2DM) treatment. Viewing to improve VDG treatment, a population pharmacokinetic (popPK) model was built to describe drug plasma, free liver and muscle concentrations determined by microdialysis in healthy and diabetic animals following 50 mg/kg i.v. bolus administration. A four‐compartment popPK model with linear elimination and bidirectional transport between tissues and the central compartment described the data with diabetes as a covariate in Q 1 and Q out,liver . The pharmacokinetic parameters of VDG were scaled to humans using allometry, and used to simulate VDG tissue concentrations in patients with T2DM and relate them with the DPP‐4 inhibition by an Imax model. The efficacy of VDG was evaluated considering 80% and 92% DP‐IV inhibition during the entire dosing interval. VDG 100 mg q24 h achieved 80% DPP‐4 inhibition in plasma, but not in tissues. Although q12 h dosing interval reached 80% enzyme inhibition in plasma for > 25 mg doses, only the 100 mg reached this goal in muscle. The 92% enzyme inhibition was achieved in plasma for 50 and 100 mg q12 h but none of the dose regimens investigated reached this inhibition in tissues.

2026-02-01·Comprehensive Physiology

Vildagliptin and Omarigliptin Differentially Bind to DPP‐4 Homodimers and Modulate Osteoclast‐Mediated Bone Resorption

Article

作者: Thongbunchoo, Jirawan ; Svasti, Saovaros ; Charoenphandhu, Narattaphol ; Wongdee, Kannikar ; Teerapornpuntakit, Jarinthorn ; Panmanee, Jiraporn ; Chattipakorn, Siriporn ; Apaijai, Nattayaporn ; Aeimlapa, Ratchaneevan ; Panupinthu, Nattapon ; Chattipakorn, Nipon ; Sa‐nguanmoo, Piangkwan

ABSTRACT:

Increased fracture risk in prediabetes and diabetes mellitus partly arises from bone collagen damage and enhanced bone resorption. Certain antidiabetic agents—particularly thiazolidinediones—paradoxically aggravate bone loss and fractures, especially in postmenopausal women with osteoporosis. However, dipeptidyl peptidase‐4 (DPP‐4) inhibitors (e.g., vildagliptin and omarigliptin) might help prevent diabetic osteopathy, although variable outcomes have been observed due to unknown mechanisms. Herein, we used high‐fat diet‐fed rats to demonstrate that oral administration of vildagliptin for 4 weeks not only alleviated insulin resistance but also improved tibial bone microstructure, as determined by bone histomorphometry. Further in vitro investigations in primary osteoblasts showed that both vildagliptin and omarigliptin similarly increased osteoblast viability, rather than upregulating the expression of osteoblast‐specific genes (e.g., Runx2 and alkaline phosphatase). We also used primary multinucleated osteoclasts to elucidate how the two DPP‐4 inhibitors modulated osteoclast functions. Interestingly, only omarigliptin, but not vildagliptin, reduced the number of TRAP‐positive cells and the mRNA expression of osteoclast‐specific genes (e.g., RANK and cathepsin K). In silico molecular dynamics revealed that omarigliptin and vildagliptin interacted differently with the DPP‐4 homodimer. Transient binding to one chain and tight binding to the other chain of the DPP‐4 homodimer by omarigliptin may be associated with its higher potency in inhibiting bone resorption. In conclusion, DPP‐4 inhibitors could improve bone microstructure, in part by increasing osteoblast viability and inhibiting osteoclast‐mediated bone resorption. Thus, omarigliptin may offer greater benefits to diabetic patients with osteoporosis, as it also helps suppress osteoclastogenesis and bone resorption.

2026-01-02·Expert Opinion On Drug Safety

Exploring SGLT-2 inhibitors and sarcopenia in FAERS: a post-marketing surveillance study

Article

作者: Tang, Guowen ; Yuan, Jie ; Ye, Yangli ; Kuai, Zheng ; Zhang, Xiaoyi ; Gao, Lihong

BACKGROUND:

The sodium-dependent glucose transporters 2 inhibitors (SGLT-2i) is associated with body weight loss but the composition of the losing weight remains unclear.

RESEARCH DESIGN AND METHODS:

Disproportionality analyses, including the reporting odds ratio (ROR), the proportional reporting ratio (PRR), the Bayesian confidence propagation neural network (BCPNN), and the multi- item gamma Poisson shrinker (MGPS) algorithms, were employed to quantify the signals of SGLT-2i-associated musculoskeletal and connective tissue disorders AEs.

RESULTS:

The search retrieved a total of 3,206 cases of musculoskeletal and connective tissue disorder-related AEs during the reporting period. This included 1,061 cases for Canagliflozin, 1,052 cases for Dapagliflozin, 1,074 cases for Empagliflozin, and 19 cases for Ertugliflozin. Fifteen preferred terms (PTs) with significant disproportionality were retained. No musculoskeletal and connective tissue system-related AE signals were reported for Ertugliflozin. We identified a risk of muscle necrosis with Canagliflozin use, a risk of sarcopenia with Dapagliflozin use, and a chance of muscle atrophy with Dapagliflozin and Empagliflozin prescriptions. Most cases occurred within the first month after SGLT-2i initiation, and AEs can persist beyond 360 days of use.

CONCLUSIONS:

Our study identified potential new musculoskeletal and connective tissue disorder-related AE signals associated with SGLT-2 inhibitors.

175

项与维格列汀相关的新闻（医药）

2026-01-24

·医药代表

315个国采品种，新一轮采购申报！

1~8 批国采全国统一接续采购开始企业及产品申报啦！今日，《国家组织集采药品协议期满品种接续采购公告（第1号）》发布，按照国家医疗保障局统一部署，全国各省（自治区、直辖市）和新疆生产建设兵团组成采购联盟，委托江苏省、河南省和广东省牵头，遵循“稳临床、保质量、反内卷、防围标”原则，对原国家组织集采1-8批（不含胰岛素专项采购）协议期满的品种，开展全国统一接续采购工作。据《公告》，本次接续采购医药机构需求量填报已完成，现启动企业及产品申报，具体目录如下（规格可点击「阅读原文」下载原始表格）： # 品种名称 1 阿托伐他汀口服常释剂型 2 瑞舒伐他汀口服常释剂型 3 氯吡格雷口服常释剂型 4 厄贝沙坦口服常释剂型 5 氨氯地平口服常释剂型 6 恩替卡韦口服常释剂型 7 艾司西酞普兰口服常释剂型 8 帕罗西汀口服常释剂型 9 奥氮平口服常释剂型 10 头孢呋辛酯（头孢呋辛）口服常释剂型 11 利培酮口服常释剂型 12 吉非替尼口服常释剂型 13 福辛普利口服常释剂型 14 厄贝沙坦氢氯噻嗪口服常释剂型 15 赖诺普利口服常释剂型 16 替诺福韦二吡呋酯口服常释剂型 17 氯沙坦口服常释剂型 18 依那普利口服常释剂型 19 左乙拉西坦口服常释剂型 20 伊马替尼口服常释剂型 21 孟鲁司特口服常释剂型 22 蒙脱石口服散剂 23 培美曲塞注射剂 24 氟比洛芬酯注射剂 25 右美托咪定注射剂 26 阿比特龙口服常释剂型 27 阿德福韦酯口服常释剂型 28 阿卡波糖口服常释剂型 29 阿莫西林口服常释剂型 30 阿奇霉素口服常释剂型 31 安立生坦片 32 奥美沙坦酯口服常释剂型 33 比索洛尔口服常释剂型 34 对乙酰氨基酚口服常释剂型 35 多奈哌齐口服常释剂型 36 氟康唑口服常释剂型 37 福多司坦口服常释剂型 38 格列美脲口服常释剂型 39 甲硝唑口服常释剂型 40 聚乙二醇口服散剂 41 坎地沙坦酯口服常释剂型 42 克林霉素口服常释剂型 43 铝碳酸镁咀嚼片 44 美洛昔康口服常释剂型 45 莫西沙星口服常释剂型 46 曲美他嗪缓释控释剂型 47 索利那新口服常释剂型 48 他达拉非片 49 特拉唑嗪口服常释剂型 50 替吉奥口服常释剂型 51 头孢氨苄口服常释剂型 52 头孢拉定口服常释剂型 53 辛伐他汀口服常释剂型 54 异烟肼口服常释剂型 55 吲达帕胺口服常释剂型 56 注射用紫杉醇（白蛋白结合型） 57 左西替利嗪口服常释剂型 58 阿那曲唑口服常释剂型 59 阿哌沙班口服常释剂型 60 阿扎胞苷注射剂 61 氨基葡萄糖口服常释剂型 62 氨溴索口服常释剂型 63 奥氮平口腔崩解片 64 奥美拉唑口服常释剂型 65 布洛芬缓释控释剂型 66 布洛芬颗粒剂 67 地氯雷他定口服常释剂型 68 多潘立酮口服常释剂型 69 二甲双胍缓释控释剂型 70 二甲双胍口服常释剂型 71 非布司他口服常释剂型 72 非那雄胺口服常释剂型 73 非那雄胺口服常释剂型 74 氟西汀口服常释剂型 75 枸橼酸西地那非片 76 甲钴胺口服常释剂型 77 卡培他滨口服常释剂型 78 卡托普利口服常释剂型 79 喹硫平口服常释剂型 80 来曲唑口服常释剂型 81 氯氮平口服常释剂型 82 美金刚口服常释剂型 83 孟鲁司特咀嚼片 84 孟鲁司特颗粒剂 85 匹伐他汀口服常释剂型 86 普芦卡必利口服常释剂型 87 曲美他嗪口服常释剂型 88 塞来昔布口服常释剂型 89 舍曲林口服常释剂型 90 坦洛新（坦索罗辛）缓释控释剂型 91 碳酸氢钠口服常释剂型 92 替格瑞洛口服常释剂型 93 托法替布口服常释剂型 94 维格列汀口服常释剂型 95 维生素B6口服常释剂型 96 西酞普兰口服常释剂型 97 西替利嗪口服常释剂型 98 缬沙坦口服常释剂型 99 盐酸达泊西汀片 100 依托考昔口服常释剂型 101 乙胺丁醇口服常释剂型 102 右佐匹克隆口服常释剂型 103 左乙拉西坦口服液体剂 104 左乙拉西坦注射用浓溶液 105 阿莫西林颗粒剂 106 利奈唑胺口服常释剂型 107 莫西沙星氯化钠注射剂 108 左氧氟沙星滴眼剂 109 环丙沙星口服常释剂型 110 头孢地尼口服常释剂型 111 头孢克洛口服常释剂型 112 克拉霉素口服常释剂型 113 埃索美拉唑（艾司奥美拉唑）口服常释剂型 114 氨磺必利口服常释剂型 115 氨溴索注射剂 116 奥洛他定滴眼剂 117 吡嗪酰胺口服常释剂型 118 丙泊酚中/长链脂肪乳注射剂 119 布洛芬口服常释剂型 120 布洛芬注射液 121 度洛西汀口服常释剂型 122 多索茶碱注射剂 123 恩格列净口服常释剂型 124 恩曲他滨替诺福韦口服常释剂型 125 格列齐特缓释控释剂型 126 加巴喷丁口服常释剂型 127 卡格列净口服常释剂型 128 喹硫平缓释控释剂型 129 洛索洛芬口服常释剂型 130 氯雷他定口服常释剂型 131 莫沙必利口服常释剂型 132 那格列奈口服常释剂型 133 帕瑞昔布注射剂 134 泮托拉唑口服常释剂型 135 泮托拉唑注射剂 136 培哚普利口服常释剂型 137 硼替佐米注射剂 138 普拉克索缓释控释剂型 139 普拉克索口服常释剂型 140 普瑞巴林口服常释剂型 141 羟苯磺酸口服常释剂型 142 瑞格列奈口服常释剂型 143 索拉非尼口服常释剂型 144 替格瑞洛口服常释剂型 145 替米沙坦口服常释剂型 146 替莫唑胺口服常释剂型 147 吸入用硫酸沙丁胺醇溶液 148 缬沙坦氨氯地平Ⅰ口服常释剂型 149 缬沙坦氢氯噻嗪口服常释剂型 150 伏立康唑口服常释剂型 151 诺氟沙星口服常释剂型 152 特比萘芬口服常释剂型 153 头孢丙烯口服常释剂型 154 左氧氟沙星口服常释剂型 155 玻璃酸钠滴眼剂 156 注射用比伐芦定 157 ω-3鱼油中/长链脂肪乳注射液 158 阿法骨化醇口服常释剂型 159 阿立哌唑口服常释剂型 160 阿昔洛韦口服常释剂型 161 埃索美拉唑（艾司奥美拉唑）注射剂 162 奥洛他定口服常释剂型 163 奥沙利铂注射剂 164 贝那普利口服常释剂型 165 贝他斯汀口服常释剂型 166 苯磺顺阿曲库铵注射剂 167 比卡鲁胺口服常释剂型 168 达比加群酯口服常释剂型 169 达比加群酯口服常释剂型 170 单硝酸异山梨酯缓释控释剂型 171 地西他滨注射剂 172 碘海醇注射剂 173 碘海醇注射剂 174 碘克沙醇注射剂 175 度他雄胺软胶囊 176 多西他赛注射剂 177 法舒地尔注射剂 178 复方异丙托溴铵吸入剂 179 格列吡嗪缓释控释剂型 180 格列吡嗪口服常释剂型 181 格隆溴铵注射液 182 更昔洛韦注射剂 183 枸橼酸氢钾钠颗粒 184 吉西他滨注射剂 185 兰索拉唑注射剂 186 乐卡地平口服常释剂型 187 利伐沙班口服常释剂型 188 利伐沙班口服常释剂型 189 利伐沙班口服常释剂型 190 硫辛酸注射剂 191 罗哌卡因注射剂 192 氯化钾缓释控释剂型 193 美托洛尔口服常释剂型 194 米格列醇口服常释剂型 195 米索前列醇口服常释剂型 196 帕洛诺司琼注射剂 197 沙格列汀口服常释剂型 198 文拉法辛缓释控释剂型 199 西那卡塞口服常释剂型 200 胸腺法新注射剂 201 异丙嗪口服常释剂型 202 异丙托溴铵吸入剂 203 脂肪乳氨基酸葡萄糖注射剂 204 中/长链脂肪乳注射剂 205 注射用盐酸苯达莫司汀 206 紫杉醇注射剂 207 阿奇霉素注射剂 208 布地奈德吸入剂 209 氟康唑注射剂型 210 利奈唑胺葡萄糖注射剂 211 莫西沙星滴眼剂 212 替硝唑口服常释剂型 213 头孢呋辛注射剂 214 头孢曲松注射剂 215 头孢他啶注射剂 216 头孢唑林注射剂型 217 左氧氟沙星注射剂型 218 阿法替尼口服常释剂型 219 阿立哌唑口腔崩解片 220 昂丹司琼注射剂 221 奥美拉唑注射剂 222 奥曲肽注射剂 223 奥司他韦口服常释剂型 224 吡格列酮口服常释剂型 225 丙酚替诺福韦口服常释剂型 226 醋酸钙口服常释剂型 227 单硝酸异山梨酯口服常释剂型 228 碘帕醇注射剂 229 厄洛替尼口服常释剂型 230 二甲双胍维格列汀口服常释剂型 231 氟桂利嗪口服常释剂型 232 氟哌噻吨美利曲辛口服常释剂型 233 磺达肝癸钠注射剂 234 甲磺酸仑伐替尼胶囊 235 咖啡因注射剂 236 拉考沙胺口服常释剂型 237 来氟米特口服常释剂型 238 利多卡因注射剂 239 罗库溴铵注射剂 240 吗替麦考酚酯口服常释剂型 241 美托洛尔缓释剂型 242 米力农注射剂 243 帕立骨化醇注射剂 244 帕洛诺司琼注射剂 245 普萘洛尔口服常释剂型 246 舒尼替尼口服常释剂型 247 特布他林吸入剂 248 替罗非班注射剂型 249 硝苯地平缓释剂型 250 硝苯地平控释剂型 251 盐酸鲁拉西酮片 252 盐酸美金刚缓释胶囊 253 伊班膦酸注射剂 254 伊立替康注射剂 255 依巴斯汀口服常释剂型 256 依达拉奉注射剂型 257 依替巴肽注射剂 258 依折麦布口服常释剂型 259 注射用替莫唑胺 260 唑来膦酸注射剂 261 唑来膦酸注射剂 262 甲泼尼龙口服常释剂型 263 甲泼尼龙注射剂 264 甲泼尼龙注射剂 265 奥硝唑口服常释剂型 266 克林霉素磷酸酯注射剂 267 罗红霉素口服常释剂型 268 头孢克洛口服液体剂 269 头孢克肟颗粒剂 270 头孢克肟口服常释剂型 271 头孢美唑注射剂型 272 头孢米诺注射剂 273 美罗培南注射剂 274 米卡芬净注射剂 275 替加环素注射剂 276 头孢吡肟注射剂型 277 阿加曲班注射剂 278 阿托西班注射剂 279 氨甲环酸注射剂型 280 氨氯地平阿托伐他汀口服常释剂型 281 丙氨酰谷氨酰胺注射剂 282 丙戊酸钠注射剂 283 非洛地平非洛地平Ⅱ缓释控释剂型 284 呋塞米注射剂 285 骨化三醇口服常释剂型 286 甲钴胺注射剂 287 奥司他韦干混悬剂 288 氯沙坦氢氯噻嗪口服常释剂型 289 米氮平口服常释剂型 290 那屈肝素(那曲肝素)注射剂 291 生长抑素注射剂 292 酮咯酸氨丁三醇注射剂 293 托拉塞米注射剂 294 熊去氧胆酸口服常释剂型 295 奥普力农注射剂 296 依诺肝素注射剂 297 左氨氯地平(左旋氨氯地平)口服常释剂型 298 左布比卡因注射剂 299 左卡尼汀注射剂 300 阿莫西林克拉维酸口服常释剂型 301 阿莫西林克拉维酸注射剂 302 氨曲南注射剂 303 奥硝唑注射剂型 304 复方磺胺甲噁唑口服常释剂型 305 甲硝唑注射剂型 306 利福平利福平Ⅱ口服常释剂型 307 头孢地尼颗粒剂 308 头孢西丁注射剂型 309 头孢地嗪注射剂 310 比阿培南注射剂 311 达托霉素注射剂 312 伏立康唑注射剂 313 哌拉西林他唑巴坦注射剂 314 头孢哌酮舒巴坦注射剂 315 头孢噻肟注射剂申报时间及方式企业及产品申报提交时间：2026年1月23日-2026年2月2日17时。修改或补充材料时间：2026年1月23日-2026年2月3日17时前。《公告》说明，未在相应规定的时间内完成申报提交和修改、补充材料的，视为放弃参与本次接续采购。截止时间如有调整，以后续公告为准。近日热点阅读： 2026，医药代表的三大危机只会“讲药”的医药代表，没有市场了 A司再度上榜！不服不行勃林格荣膺“中国杰出雇主” 上药天普荣膺中国杰出雇主认证医药行业三大央企披露高管年薪安斯泰来蝉联“中国杰出雇主” 欧加隆蝉联“中国杰出雇主” 费卡中国连续荣膺中国杰出雇主赵萍：跨国药企的“赢”，如何书写？一药企被诉拖欠研发费用这些药企上榜创新药“华山奖” 通化东宝任命两名副总裁日本药企2026涨薪幅度定了医保支持创新，国产好药加速惠及患者跨国药企裁员，近190名医药代表面临失业明年3月，6000+医药精英赴约西贝这事儿，医药老炮儿怎么处理？这家药企年会放大招！把医药人看酸了中国医药又查一人多家药企，高管变动医药代表的五种类型，你属于哪一类？打通肥胖管理“最后一公里”，诺和诺德行动了 4个药品，暂停采购年薪曾达870万元，一药企CEO辞职医药巨头，再次补税三千多万徐向平辞任九芝堂副总经理拜耳中国12月热招岗位费森尤斯卡比全国职位大放送辉瑞中国成立新事业部，全国岗位网红A司，风口加速扩招中最新药企内部招聘（1月22日更新） #跨国药企在进博会医药代表伴您成长！

带量采购

2026-01-24

·CVDAILY

全球糖尿病速递（第024期）｜替尔泊肽、视网膜病变、虚拟助手、吸入胰岛素、肺癌

*本资料仅供医疗卫生专业人士参考，请勿向非医疗卫生专业人士发放截至01月24日15点59分，近期共有 456 本期刊发布了 871 篇文章，其中糖尿病相关的文章共 325 篇，覆盖 30 个领域的内容。中国专家参与发表的文章有 77 篇。今日，影响因子最高的文章刊登在 Journal of the American Medical Association (IF: 55.000) 期刊上。今日头条 Headlines 01 Ophthalmology IF: 09.500 替尔泊肽与降低糖尿病视网膜病变及相关并发症风险：一项美国多中心队列研究 Shah, Jaffer, Razavi, Peyman, Festok, Muhamad, Ahmed, Harris, Mahrous, M Abdallah, Kovacs, Kyle D, etc. 近日，一项发表于眼科权威期刊《Ophthalmology》的大型回顾性研究揭示了新型药物替尔泊肽（Tirzepatide）在糖尿病管理中可能带来的额外益处。该研究首次系统评估了替尔泊肽对糖尿病视网膜病变（DR）这一常见且严重的微血管并发症的长期影响。研究团队利用覆盖广泛的TriNetX美国协作医疗数据库，开展了一项基于人群的回顾性队列分析。研究聚焦于患有糖尿病且伴有超重或肥胖状况的患者群体，旨在探究起始使用替尔泊肽与仅接受生活方式干预，在预防和延缓糖尿病视网膜病变方面是否存在差异。研究设计严谨，为尽量减少混杂因素的影响，研究人员采用了倾向评分匹配的方法。他们将每位起始使用替尔泊肽的患者，与一位在人口统计学特征、代谢指标（如糖化血红蛋白、体重指数）以及系统性共病（如高血压、高血脂）等方面高度相似，但仅接受生活方式干预且未使用任何减重药物的患者进行配对。经过匹配，最终共有173,846名患者被纳入分析，平均年龄为56.9岁，其中女性占比52.0%，两组各包含86,923名患者，确保了比较的均衡性。研究的主要观察终点是糖尿病视网膜病变的发生、向更严重阶段（如从非增殖性发展为增殖性）的进展，以及因视网膜病变而需要接受特定眼科干预的情况，例如玻璃体内注射抗血管内皮生长因子（抗-VEGF）药物或进行全视网膜激光光凝术。经过为期12个月的随访，分析结果呈现出显著差异。与单纯依靠生活方式干预的对照组相比，使用替尔泊肽的患者发生各类糖尿病视网膜病变事件的风险普遍降低。具体数据显示，替尔泊肽组患者新发轻度非增殖性糖尿病视网膜病变的风险相对降低了约14%，进展为威胁视力的增殖性糖尿病视网膜病变的风险降低了约30%。替尔泊肽在降低糖尿病视网膜病变相关严重并发症风险方面表现出更为明显的优势。研究结果显示，使用替尔泊肽的患者，发生合并有视力损害风险的糖尿病性黄斑水肿的风险降低了约38%，发生玻璃体积血的风险降低了约39%，而发生可能导致永久性视力丧失的牵拉性视网膜脱离的风险更是大幅降低了约63%。这些风险的降低直接转化为临床干预需求的减少。数据分析表明，与对照组相比，替尔泊肽组患者在未来一年内需要接受玻璃体内抗-VEGF注射以治疗黄斑水肿或新生血管的风险降低了约52%，需要接受全视网膜激光光凝术以控制增殖性病变的风险降低了约39%。综上所述，这项基于大规模真实世界数据的研究表明，对于患有糖尿病且超重或肥胖的患者，使用替尔泊肽治疗，与仅采取生活方式干预相比，可能与更低的糖尿病视网膜病变新发及进展风险相关联。此外，替尔泊肽的使用还可能显著降低因视网膜病变导致严重并发症的发生率，并减少患者后续接受侵入性眼科治疗的需求。这一发现为临床医生在制定糖尿病综合管理方案，特别是对于有视网膜病变风险的患者选择治疗方案时，提供了新的重要参考依据。本文由牛祥编辑扫描二维码查看源文 Ophthalmology | Ahead of Print. 10.1016/j.ophtha.2026.01.013 02 JAMA Network Open IF: 09.700 互动虚拟助手对2型糖尿病老年患者健康促进的干预研究：IVAM-ED随机临床试验 Matzenbacher, Lucas S, da Costa, Frederico Ludwig, de Barros, Laura Gomes Boabaid, Gheno, Vicenzo, Maia, Isabela Semmelmann, Blank, Luiza Machado, etc. 一项最新发表的随机临床试验显示，一款基于智能音箱的互动虚拟助手，能够显著改善老年2型糖尿病患者的心理健康状况、生活质量、疾病自我管理行为以及血糖控制水平。该研究结果发表在JAMA Network Open期刊上。该研究旨在探究技术设备结合行为干预模型，在支持老年糖尿病患者健康管理方面的潜力。研究指出，老年糖尿病患者常面临较高的心理困扰，这可能使疾病管理复杂化，并对健康结局产生负面影响。该研究于2023年6月22日至2024年2月8日期间，在巴西的一家学术医疗中心开展。研究共纳入了112名年龄在65岁及以上、确诊为2型糖尿病的参与者，他们的平均年龄为72.5岁，平均糖化血红蛋白水平为7.9%。参与者被随机分为两组，干预组在家中使用了预编程的智能音箱设备（Amazon Echo Dot）12周，而对照组则继续接受常规医疗护理。研究人员在12周的干预期结束后，对参与者的多项指标进行了评估。主要结局是心理困扰程度，采用自评问卷进行测量。结果显示，与常规护理组相比，使用智能音箱的干预组参与者的心理困扰评分显著更低，两组间的调整后平均差值为-1.46分，具有统计学意义。这表明该干预有效减轻了患者的心理困扰。除了主要结局，研究还观察了一系列重要的次要结局。在生活质量方面，干预组比常规护理组有显著提升。在糖尿病自我护理行为的依从性上，干预组也表现出明显改善。更重要的是，在血糖控制的关键指标——糖化血红蛋白上，干预组比对照组平均降低了0.48%，达到了具有临床意义的改善水平。然而，在感知压力方面，两组之间未观察到显著差异。整个研究过程中，没有参与者因不良事件而退出试验。该研究的结论表明，这种通过智能设备提供的、易于实施的行为干预，能够为老年2型糖尿病患者带来多方面的健康获益。它不仅有助于缓解患者的心理痛苦，还能促进其积极进行自我管理，并最终实现更好的血糖控制效果。这为在社区和家庭环境中推广数字化健康管理工具提供了新的证据。本文由牛祥编辑扫描二维码查看源文 JAMA Network Open | Volume 9, Issue 1 10.1001/jamanetworkopen.2025.53508 03 Diabetes Technol Ther IF: 06.300 糖尿病吸入胰岛素应用者的肺癌与慢性阻塞性肺疾病真实世界发病率 Cowart, Kevin, Everich, Hannah, Flores, Francisco, Harris, Marisa, Randall, Daniel, Sammartano, Lauren, etc. 一项新近发表于《Diabetes technology & therapeutics》的研究，利用大规模真实世界数据，评估了吸入式胰岛素与速效胰岛素类似物在成年糖尿病患者中的肺部安全性，重点关注肺癌与慢性阻塞性肺疾病风险。该研究结果为临床决策提供了重要参考。研究团队利用TriNetX网络数据库，回顾性地纳入了患有1型或2型糖尿病的成年患者。这些患者被分为两组：一组曾处方吸入式胰岛素，另一组则处方速效胰岛素类似物。为减少混杂因素的影响，研究者对两组人群进行了倾向性评分匹配，最终使两组在基线特征上具有可比性。研究结果显示，在肺癌风险方面，两组患者未观察到统计学上的显著差异。具体而言，吸入式胰岛素组与速效胰岛素类似物组发生任何肺癌的风险比值为1，其95%置信区间为0.42至2.40，P值达到0.999，表明两组风险并无不同。然而，在慢性阻塞性肺疾病方面，吸入式胰岛素组发生慢性阻塞性肺疾病复合结局的风险，显著高于速效胰岛素类似物组。风险比值为3.45，意味着前者的风险是后者的约3.5倍，且该差异具有高度的统计学意义。不过，研究者也指出，两组患者的绝对风险均处于较低水平。基于这些发现，研究者得出结论：在这项真实世界研究中，未发现吸入式胰岛素的使用与肺癌风险增加之间存在关联。但同时，吸入式胰岛素与慢性阻塞性肺疾病风险的升高相关，尽管绝对风险较低。研究者强调，该关联的生物学合理性尚不明确，并非结论性的。研究者同时指出了本研究的局限性。作为一项回顾性观察性研究，其设计本身可能受到混杂因素及信息偏倚（如监测偏倚）的影响，因此难以做出确切的因果推断。尽管如此，这些发现强调了继续监测和评估吸入式胰岛素长期肺部安全性的必要性。本文由牛祥编辑扫描二维码查看源文 Diabetes Technol Ther | Ahead of Print. 10.1177/15209156251387102 中国发表（77） China BMC medicine IF: 08.300Ahead of Print.No.01Association of short-term exposure to ambient air pollutants with liver function and mediation by fasting insulin: evidence from a rural cohort in China短期暴露于环境空气污染物与肝功能的关联及空腹胰岛素的中介作用：来自中国农村队列的证据DOI: 10.1186/s12916-026-04645-x npj science of food IF: 07.800Ahead of Print.No.02Cooked meat-derived extracellular vesicles ssc-miR-1 induces metabolic disorders in the mice liver via PI3k/AKT pathway烹饪肉食来源的细胞外囊泡ssc-miR-1通过PI3K/AKT通路诱导小鼠肝脏代谢紊乱DOI: 10.1038/s41538-026-00709-7 Am J Vet Res IF: 01.400Ahead of Print.No.03Hydroxyacyl coenzyme A dehydrogenase trifunctional multienzyme complex subunit α depletion dysregulates hepatic energy and lipid metabolism in dairy cows hepatocytes: a multiomic integration analysis羟酰基辅酶A脱氢酶三功能多酶复合体α亚基缺失扰乱奶牛肝细胞的能量与脂质代谢：一项多组学整合分析DOI: 10.2460/ajvr.25.09.0336 BMC endocrine disorders IF: 03.300Ahead of Print.No.04Calcitonin-negative medullary thyroid carcinoma combined with multifocal papillary thyroid carcinoma: a case report and literature review降钙素阴性甲状腺髓样癌合并多灶性甲状腺乳头状癌：一例报告并文献复习DOI: 10.1186/s12902-026-02172-7 BMC microbiology IF: 04.200Ahead of Print.No.05Faecal microbiome and serum metabolomics: potential biomarkers for type 2 diabetes粪便微生物组与血清代谢组学：2型糖尿病的潜在生物标志物DOI: 10.1186/s12866-025-04571-7 Nature reviews. Nephrology IF: 39.800Ahead of Print.No.06Effects of social determinants of health on the landscape of kidney disease健康的社会决定因素影响肾脏疾病图景DOI: 10.1038/s41581-026-01052-6 Int J Biol Macromol IF: 08.500Ahead of Print.No.07Pro-angiogenic dual-crosslinked collagen bioinks for precise cell-laden DLP 3D printing and rapid vascularized diabetic wound repair用于精确负载细胞DLP 3D打印和快速血管化糖尿病伤口修复的促血管生成双交联胶原生物墨水DOI: 10.1016/j.ijbiomac.2026.150408 Experimental Eye Research IF: 02.700Ahead of Print.No.08Elevated Expression of Hsa_circ_0053004 in Peripheral Blood Mononuclear Cells Correlates with Endothelial Dysfunction in Diabetic Retinopathy外周血单个核细胞中hsa_circ_0053004的表达升高与糖尿病视网膜病变中的内皮功能障碍相关DOI: 10.1016/j.exer.2026.110880 Life sciences IF: 05.100Ahead of Print.No.09Exogenous hydrogen sulphide alleviates diabetes-associated cognitive decline by inhibiting ferroptosis through Nrf2/GPX4 signalling pathway外源性硫化氢通过激活Nrf2/GPX4信号通路抑制铁死亡，缓解糖尿病相关认知衰退DOI: 10.1016/j.lfs.2026.124220 Colloids Surf B Biointerfaces IF: 05.600Ahead of Print.No.10A self-adapting DNA-crosslinked hydrogel reprograms macrophage polarization and angiogenesis for synergistic repair of diabetic wounds一种自适性DNA交联水凝胶通过重编程巨噬细胞极化与血管生成协同修复糖尿病伤口DOI: 10.1016/j.colsurfb.2026.115465 International dental journal IF: 03.700Ahead of Print.No.11Exploration Novel Therapeutic Targets for Periodontitis via Stress Granules Biomarkers通过应激颗粒生物标志物探索牙周炎的新型治疗靶点DOI: 10.1016/j.identj.2025.109390 Biomaterials advances IF: 06.000Ahead of Print.No.12A novel ROS switcher potentiates the type-I photodynamic effect of sodium zinc chlorophyllin against Pseudomonas aeruginosa in diabetic wounds一种新型活性氧转换开关可增强锌叶绿酸钠对糖尿病伤口中铜绿假单胞菌的I型光动力效应DOI: 10.1016/j.bioadv.2026.214721 Biomaterials advances IF: 06.000Ahead of Print.No.13Multifunctional conductive hydrogel integrating exosome delivery and electrical stimulation for enhanced diabetic wound healing整合外泌子递送与电刺激的多功能导电水凝胶促进糖尿病伤口愈合DOI: 10.1016/j.bioadv.2026.214716 J Nutr Health Aging IF: 04.000Ahead of Print.No.14An atlas of associations between dietary nutrients and the risk of 36 major chronic diseases膳食营养素与36种主要慢性病风险关联图集DOI: 10.1016/j.jnha.2026.100785 Obesity surgery IF: 03.100Ahead of Print.No.15Global Trends in Bariatric Surgery for the Treatment of Metabolic Syndrome: A Bibliometric and Visualization Analysis代谢综合征治疗中减重手术的全球趋势：A Bibliometric and Visualization AnalysisDOI: 10.1007/s11695-026-08489-5 Communications biology IF: 05.100Ahead of Print.No.16Obesity impairs spermatogenesis via Leydig cell ferroptosis induced by liver-derived exosomal miR-122-5p肥胖通过肝脏来源外泌体miR-122-5p诱导Leydig细胞铁死亡进而损害精子发生DOI: 10.1038/s42003-026-09612-z npj science of food IF: 07.800Ahead of Print.No.17Computational-experimental study reveals direct target and bioactives of Ajania fruticulosa against NAFLD via TLR2/NF-κB/PPAR-γ signaling计算与实验研究揭示黄花蒿水提物通过TLR2/NF-κB/PPAR-γ信号通路对抗NAFLD的直接靶点与活性成分DOI: 10.1038/s41538-026-00722-w Journal of Genetics and Genomics IF: 07.100Ahead of Print.No.18Lipid metabolism and metabolites: emerging roles in systemic physiology and metabolic diseases脂质代谢与代谢物：系统生理学与代谢疾病中的新兴作用DOI: 10.1016/j.jgg.2026.01.006 Experimental gerontology IF: 04.300Ahead of Print.No.19Association between weight-adjusted waist index (WWI) and multimorbidity: Evidence from NHANES and prospective validation in CHARLS体重调整腰围指数（WWI）与多重共病的关联：基于NHANES的证据及CHARLS的前瞻性验证DOI: 10.1016/j.exger.2026.113044 Bioorganic chemistry IF: 04.700Ahead of Print.No.20Design, synthesis and biological evaluation of hydroxycinnamoylamides derivatives as potent glucosidase inhibitors羟基肉桂酰胺衍生物作为强效葡萄糖苷酶抑制剂的设计、合成与生物学评价DOI: 10.1016/j.bioorg.2025.109453 Cell reports IF: 06.900Ahead of Print.No.21Lysosome-localized IRTKS condensates promote mTORC1 activity leading to MASLD and HCC溶酶体定位的IRTKS凝聚体通过激活mTORC1导致MASLD和HCCDOI: 10.1016/j.celrep.2025.116893 Curr Opin Gastroenterol IF: 02.500Ahead of Print.No.22Mechanistic insights into pancreatic duct pressure: from basic physiology to translational implications胰腺导管压力：从基础生理到转化应用的机制新见解DOI: 10.1097/MOG.0000000000001147 JMIR research protocols IF: 01.500Volume 15, Issue No.23Traditional Chinese Medicine Syndrome Differentiation of Adult Patients With Type 2 Diabetes and Metabolic Syndrome: Protocol for a Cross-Sectional Study成人2型糖尿病合并代谢综合征患者的中医证型鉴别：一项横断面研究方案DOI: 10.2196/86217 Biomolecules & biomedicine IF: 02.200Ahead of Print.No.24Prediabetes and the risk of incident chronic kidney disease in adults: A systematic review and meta-analysis成人糖尿病前期与慢性肾脏病发病风险：一项系统综述和荟萃分析DOI: 10.17305/bb.2026.13524 Reproduction IF: 03.700Volume 171, Issue 1No.25Deficiency of the GnIH/GPR147 system induces asthenozoospermia via PI3K-mediated metabolic and apoptotic dysregulationGnIH/GPR147系统缺陷通过PI3K介导的代谢与凋亡失调诱导弱精子症DOI: 10.1093/reprod/xaaf017 Reproduction IF: 03.700Ahead of Print.No.26High dietary fructose induces the senescence of granulosa cells by enhancing O-GlcNAcylation高果糖饮食通过增强O-GlcNAc糖基化诱导颗粒细胞衰老DOI: 10.1093/reprod/xaag005 Int J Mol Med IF: 05.800Volume 57, Issue 3No.27Research progress on the effects of macrophage‑derived exosomes on muscle factors IGF‑1 and FGF‑2 mediating musculoskeletal crosstalk molecular signaling pathway on bone metabolism (Review)巨噬细胞来源外泌体通过调节肌肉因子IGF-1和FGF-2介导肌肉骨骼互作信号通路影响骨代谢的研究进展（综述）DOI: 10.3892/ijmm.2026.5738 Molecular Medicine Reports IF: 03.500Volume 33, Issue 3No.28PDX1 in human cancers: Molecular mechanisms, dual roles and clinical implications (Review)PDX1在人类癌症中的作用：分子机制、双重角色及临床意义（综述）DOI: 10.3892/mmr.2026.13806 Annals of biomedical engineering IF: 05.400Ahead of Print.No.29T(2) Mapping at 3 T of Cartilage and Menisci in Patients with Diabetes Mellitus3T磁共振T2映射评估糖尿病患者的软骨与半月板DOI: 10.1007/s10439-026-03990-5 Science China. Life Sciences IF: 09.500Ahead of Print.No.30Lung function impairment and risk of sepsis and sepsis-related mortality: a large cohort study with over 310,000 participants肺功能损伤与脓毒症发生及脓毒症相关死亡风险：一项涵盖超31万人的大型队列研究DOI: 10.1007/s11427-025-3140-8 Molecular biology reports IF: 02.800Volume 53, Issue 1No.31UFMylation in lipid metabolism disorders-associated diseasesUFMylation在脂质代谢紊乱相关疾病中的作用DOI: 10.1007/s11033-026-11452-3 The FASEB journal : IF: 04.200Volume 40, Issue 2No.32Maternal Fructose Intake During Pregnancy Induced the Hepatic Glucose Homeostasis Imbalance in the Offspring by Inhibiting Glucokinase孕期母体果糖摄入通过抑制葡萄糖激酶诱发子代肝脏葡萄糖稳态失衡DOI: 10.1096/fj.202503081R Biomaterials science IF: 05.700Ahead of Print.No.33A dual-network Bletilla striata polysaccharide hydrogel for PPAR-mediated macrophage polarization and accelerated diabetic wound healing一种基于PPAR介导的巨噬细胞极化加速糖尿病伤口愈合的双网络白及多糖水凝胶DOI: 10.1039/d5bm01617g Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.34Evaluating WHtR and WC cut-offs for abdominal obesity among children and adolescents: Insights from three National Surveys in China评估中国儿童青少年腹型肥胖的腰围身高比和腰围切点：基于三次全国学生体质与健康调研的启示DOI: 10.1111/dom.70488 Int J Mol Med IF: 05.800Volume 57, Issue 3No.35Mangiferin in human disease: Multifaceted mechanisms and applications (Review)芒果苷在人类疾病中的研究：多面机制与应用（综述）DOI: 10.3892/ijmm.2026.5736 Int J Mol Med IF: 05.800Volume 57, Issue 3No.36Epigenetic dysregulation of B‑cells in autoimmune diseases and lymphomas (Review)自身免疫性疾病和淋巴瘤中B细胞的表观遗传失调DOI: 10.3892/ijmm.2026.5739 Int J Mol Med IF: 05.800Volume 57, Issue 3No.37[Retracted] DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in ratsDDAH2通过激活DDAH/ADMA/NOS/NO通路减轻大鼠糖尿病心肌病的心肌纤维化DOI: 10.3892/ijmm.2026.5734 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.38Machine learning-based online prediction of nocturnal hypoglycemia in elderly patients with type 2 diabetes基于机器学习的老年2型糖尿病患者夜间低血糖在线预测DOI: 10.3389/fendo.2025.1685969 Int J Ophthalmol IF: 01.800Volume 19, Issue 2No.39Detecting altered spontaneous activities of different brain areas in diabetic vitreous hemorrhage patients: a magnetic resonance imaging study应用磁共振成像探测糖尿病玻璃体积血患者不同脑区的自发性活动改变DOI: 10.18240/ijo.2026.02.09 Journal of clinical ultrasound : IF: 01.400Ahead of Print.No.40Analysis of Risk Factors for Patency Rate After Ultrasound-Guided PTA for AVF Stenosis超声引导PTA治疗AVF狭窄后通畅率的风险因素分析DOI: 10.1002/jcu.70190 Advances in wound care IF: 05.600Ahead of Print.No.41Efficacy and Safety of Human Amniotic Membrane for Chronic Wounds: A Systematic Review and Meta-Analysis of Clinical Trials人羊膜治疗慢性伤口的有效性与安全性：一项临床试验的系统回顾与荟萃分析DOI: 10.1177/21621918251411808 Lipids in health and disease IF: 04.200Volume 25, Issue 1No.42Risk prediction of multiple cardiometabolic diseases in middle-aged and older adults using lipid metabolism biomarkers and derived composite measures based on machine learning: a prospective cohort study of CHARLS基于机器学习，利用脂质代谢标志物及其衍生复合指标预测中老年人心血管代谢共病的风险：CHARLS前瞻性队列研究DOI: 10.1186/s12944-025-02820-2 Frontiers in immunology IF: 05.900Volume 16, Issue No.43Correction: The role of immune cells-mediated memory in weight cycling, glucose disorders and insulin resistance更正：免疫细胞介导的记忆在体重循环、血糖紊乱及胰岛素抵抗中的作用DOI: 10.3389/fimmu.2025.1773368 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.44Cangfu Daotan decoction treats PCOS-IR through the IL6/JAK2/STAT3/FOXO4 signaling pathway苍附导痰汤通过IL6/JAK2/STAT3/FOXO4信号通路治疗多囊卵巢综合征胰岛素抵抗DOI: 10.3389/fendo.2025.1661000 Frontiers in nutrition IF: 05.100Volume 12, Issue No.45Assessing the potency of vitamin D augmentation on saccharometric indices in type 2 diabetes: a meta-analysis评估维生素D补充对2型糖尿病血糖指标的效能：一项Meta分析DOI: 10.3389/fnut.2025.1677686 Frontiers in nutrition IF: 05.100Volume 12, Issue No.46Metabolism, senescence, and natural products: new perspectives on wound healing in diabetes代谢、衰老与天然产物：糖尿病伤口愈合的新视角DOI: 10.3389/fnut.2025.1746827 Mini Rev Med Chem IF: 03.300Ahead of Print.No.47Bitter Compounds as Multifunctional Agents against Diabetes-associated Cognitive Dysfunction: Bridging Metabolic Regulation and Neuroprotection苦味化合物作为抗糖尿病相关认知功能障碍的多功能药物：连接代谢调控与神经保护DOI: 10.2174/0113895575414424251128113543 Can J Neurol Sci IF: 02.200Ahead of Print.No.48Peripheral Indicators of Alzheimer's Disease Pathology in Women With Polycystic Ovary Syndrome: A Case-Control Study多囊卵巢综合征女性阿尔茨海默病病理的外周指标：一项病例对照研究DOI: 10.1017/cjn.2025.10495 Front Mol Biosci IF: 04.000Volume 12, Issue No.49Research progress on oral glucagon-like peptide-1 receptor agonists in the treatment of diabetes mellitus type 2口服胰高血糖素样肽-1受体激动剂在2型糖尿病治疗中的研究进展DOI: 10.3389/fmolb.2025.1729904 FCVM IF: 02.900Volume 12, Issue No.50Machine learning-based prediction model for 30-day readmission risk in elderly patients with type 2 diabetes mellitus and heart failure: a retrospective cohort study with SHAP interpretability analysis基于机器学习的老年2型糖尿病合并心力衰竭患者30天再入院风险预测模型：一项结合SHAP可解释性分析的回顾性队列研究DOI: 10.3389/fcvm.2025.1673159 Frontiers in nutrition IF: 05.100Volume 12, Issue No.51Effect of preoperative oral isomaltulose on insulin resistance and glycemic variability in patients with type 2 diabetes mellitus: a randomized controlled trial术前口服异麦芽酮糖对2型糖尿病患者胰岛素抵抗及血糖变异性的影响：一项随机对照试验DOI: 10.3389/fnut.2025.1718843 Current diabetes reviews IF: 01.900Ahead of Print.No.52Chain Mediating Role of Illness Perception and Fear of Hypoglycemia in Impaired Hypoglycemic Awareness and Mild Cognitive Impairment in Patients with Type 2 Diabetes Mellitus疾病感知和低血糖恐惧在2型糖尿病患者低血糖感知受损与轻度认知障碍间的链式中介作用DOI: 10.2174/0115733998418191251127053922 Current diabetes reviews IF: 01.900Ahead of Print.No.53Targeting the Gut Microbiota in the Treatment of Type 2 Diabetes: Dietary Interventions, Microbial Preparations, and Fecal Transplantation靶向调控肠道菌群治疗2型糖尿病：饮食干预、微生物制剂与粪菌移植DOI: 10.2174/0115733998411102251127094217 Endocr Metab Immune Disord Drug Targets IF: 02.000Ahead of Print.No.54Gamma-Glutamyl Transferase and Male Reproductive Hormone Levels in Men with Type 2 Diabetes: A Cross-Sectional Studyγ-谷氨酰转移酶与2型糖尿病男性患者的生殖激素水平：一项横断面研究DOI: 10.2174/0118715303392699251016073511 Frontiers in nutrition IF: 05.100Volume 12, Issue No.55Mapping the evolution of botanical interventions for diabetic neuropathy: a two-database bibliometric landscape from 2005 to mid-2025映射植物干预糖尿病神经病变的演进：一项2005年至2025年中期的双数据库文献计量学图景DOI: 10.3389/fnut.2025.1727582 Andrology IF: 03.400Ahead of Print.No.56Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models大鼠模型中肥胖、生殖毒物及其组合诱导的少弱精子症的综合量化研究DOI: 10.1111/andr.70171 Journal of food science IF: 03.400Volume 91, Issue 1No.57Study on Anti-Obesity Activities of Three Individual Black Soybean Meal-Derived Insoluble Dietary Fibers via Modulating Intestinal Microbiota and Their Metabolites通过调节肠道微生物群及其代谢物研究三种黑豆粕不溶性膳食纤维的抗肥胖活性DOI: 10.1111/1750-3841.70778 Frontiers in immunology IF: 05.900Volume 16, Issue No.58Bioactives and exercise synergize to modulate AMPK and inflammation生物活性物质与运动协同调节AMPK及炎症DOI: 10.3389/fimmu.2025.1670379 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.59Impact of BMI on basal LH in premenarcheal girls with idiopathic central precocious puberty体重指数对月经初潮前特发性中枢性性早熟女童基础促黄体生成素的影响DOI: 10.3389/fendo.2025.1740527 Current pharmaceutical design IF: 02.800Ahead of Print.No.60Nuciferine Prevents Obesity by Inhibiting Macrophage Inflammation Involving LGALS3, CTSB, and RBP4 Genes Based on an Integrative Analysis of Adipose Tissue Transcriptomics and Network Pharmacology基于脂肪组织转录组学与网络药理学整合分析发现荷叶碱通过靶向LGALS3、CTSB和RBP4基因抑制巨噬细胞炎症进而预防肥胖DOI: 10.2174/0113816128400528251121074807 FCVM IF: 02.900Volume 12, Issue No.61Combining triglyceride glucose-body mass index and high-sensitivity C-reactive protein to predict cardiovascular disease: results from a national cohort and a clinical verified cohort联合甘油三酯葡萄糖-体重指数和高敏C反应蛋白预测心血管疾病：来自一项全国队列和一项临床验证队列的结果DOI: 10.3389/fcvm.2025.1726615 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.62Comparison of the efficacy of antidiabetic agents in type 2 diabetes with MASLD: a network meta-analysis降糖药物治疗2型糖尿病合并代谢功能障碍相关脂肪性肝病有效性的网络Meta分析比较DOI: 10.3389/fendo.2025.1659740 Medical acupuncture IF: 00.800Volume 37, Issue 5No.63Efficacy of Abdominal Acupoints Catgut Embedding Combined with Auricular Acupressure Therapy for Abdominal Obesity: A Single-Blind Randomized Control Trial腹部穴位埋线联合耳穴压豆疗法治疗腹型肥胖的有效性：一项单盲随机对照试验DOI: 10.1089/acu.2024.0014 Diabetes Technol Ther IF: 06.300Ahead of Print.No.64Performance of the Fifth Generation of a 16-Day Continuous Glucose Monitoring System in Adults with Diabetes第五代16天连续葡萄糖监测系统在成人糖尿病患者中的性能表现DOI: 10.1177/15209156261416870 CNS Neurol Disord Drug Targets IF: 03.000Ahead of Print.No.65The Use of Benzodiazepines and Risk of Incident Type 2 Diabetes in the General Population with Insomnia在患有失眠症的普通人群中使用苯二氮䓬类药物与2型糖尿病风险的研究DOI: 10.2174/0118715273430289251128102145 Frontiers in medicine IF: 03.000Volume 12, Issue No.66Solving the diagnostic dilemma in bone infections: metagenomic next generation sequencing enhances pathogen identification accuracy破解骨感染诊断困境：宏基因组二代测序提升病原体识别准确性DOI: 10.3389/fmed.2025.1699607 Front Clin Diabetes Healthc IF: 02.200Volume 6, Issue No.67Electrical stimulation: a novel adjunct therapy for diabetic foot ulcers电刺激：糖尿病足溃疡的新型辅助疗法DOI: 10.3389/fcdhc.2025.1682871 Frontiers in public health IF: 03.400Volume 13, Issue No.68Knowledge of diabetes among nurses of primary healthcare facilities in China: a cross-sectional survey study中国基层医疗机构护士糖尿病知识水平：一项横断面调查研究DOI: 10.3389/fpubh.2025.1717127 Front Mol Biosci IF: 04.000Volume 12, Issue No.69Effect of treatment duration on the associations between three modern antidiabetic drugs and survival outcomes of lung cancer in China三类新型抗糖尿病药物治疗时长对中国肺癌患者生存结局的影响DOI: 10.3389/fmolb.2025.1701515 Frontiers in surgery IF: 01.800Volume 12, Issue No.70Risk factors for sacrococcygeal pilonidal sinus: a systematic review and meta-analysis supplemented by genetic causal assessment骶尾部藏毛窦的风险因素：系统回顾、荟萃分析及遗传因果评估补充DOI: 10.3389/fsurg.2025.1718589 Journal of diabetes research IF: 03.400Volume 2026, Issue No.71Yixiao Formula Suppresses Myocardial Fibrosis Through UpregulatingmiR-133a and Downregulating TGF-β/Smads Signal Molecules益消方通过上调miR-133a和下调TGF-β/Smads信号分子抑制心肌纤维化DOI: 10.1155/jdr/5533249 Hematology IF: 01.600Volume 31, Issue 1No.72Effect of autoimmune diseases on aplastic anemia: a bidirectional two-sample Mendelian randomization study自身免疫性疾病对再生障碍性贫血的影响：一项双向两样本孟德尔随机化研究DOI: 10.1080/16078454.2026.2617680 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.73Deep exploration and precise identification of key risk factors for diabetic peripheral neuropathy using the random forest algorithm运用随机森林算法深入探索并精准识别糖尿病周围神经病变的关键风险因素DOI: 10.3389/fendo.2025.1740545 International journal of surgery IF: 10.100Volume 112, Issue 1No.74The C-reactive protein-triglyceride glucose index (CTI) predicts mortality in cardiovascular-kidney-metabolic syndrome: a dual-cohort study with machine learning validationC反应蛋白-甘油三酯-葡萄糖指数 (CTI) 预测心血管-肾脏-代谢综合征死亡率：一项结合机器学习验证的双队列研究DOI: 10.1097/JS9.0000000000003560 Frontiers in immunology IF: 05.900Volume 16, Issue No.75Multi-omics analysis of the potential association between metabolic features of hypothyroidism in the first half of pregnancy and Th17/Treg balance基于多组学分析探讨妊娠前半期甲状腺功能减退的代谢特征与Th17/Treg平衡的潜在关联DOI: 10.3389/fimmu.2025.1656946 Endocr Metab Immune Disord Drug Targets IF: 02.000Ahead of Print.No.76Association of Fibrinogen-Like Protein 1 with Metabolic Disorders and Pregnancy Outcomes: A Case-Control Study纤维蛋白原样蛋白1与代谢紊乱及妊娠结局的关联：一项病例对照研究DOI: 10.2174/0118715303416614251106110927 J Cachexia Sarcopenia Muscle IF: 09.100Volume 17, Issue 1No.77Multi-Omics Revealed the Effects of Intrauterine Hyperglycemia Exposure on the Development of Skeletal Muscle in Offspring多组学揭示宫内高血糖暴露对子代骨骼肌发育的影响DOI: 10.1002/jcsm.70177 其他发布内容（245） More Published Articles ?eská a slovenská farmacieVolume 73, Issue E2No.01Pharmaceutical care of patients with metabolic syndrome in Slovakia - questionnaire斯洛伐克代谢综合征患者的药学服务：一项问卷调查DOI: 10.36290/csf.2024.020 Physiology & behavior IF: 02.500Volume 306, Issue No.02Moderating effects of physical activity intensity and sedentary break patterns on the association between sedentary time and cardiometabolic risk in older adults体力活动强度与久坐中断模式对老年人久坐时间与心脏代谢风险关联的调节作用DOI: 10.1016/j.physbeh.2025.115214 ?eská a slovenská farmacieVolume 73, Issue E3No.03Pharmaceutical company Norgine in Ústí nad Labem (Aussig)位于拉贝河畔乌斯季（奥西希）的Norgine制药公司DOI: 10.36290/csf.2024.034 J Chem Inf Model IF: 05.300Ahead of Print.No.04HelixSide: A Comprehensive Method for Local and Global Orientational Analysis of ProteinsHelixSide：一种用于蛋白质局部与全局取向分析的综合性方法DOI: 10.1021/acs.jcim.5c02426 J Gen Intern Med IF: 04.200Ahead of Print.No.05Engaging in Advocacy to Promote Policy Change: Incorporating Advocacy-Informed Research and Applying the PRISM Implementation Science Model参与倡导以促进政策变革：融入倡导知证研究与应用PRISM实施科学模型DOI: 10.1007/s11606-026-10169-0 Ophthalmology and therapy IF: 03.200Ahead of Print.No.06A Phase III Randomized Trial Comparing Efficacy, Safety, and Immunogenicity of ZRC-3285 vs. Eylea(®) in Patients with Wet Age-Related Macular Degeneration一项在湿性年龄相关性黄斑变性患者中比较ZRC-3285与Eylea®的有效性、安全性和免疫原性的III期随机试验DOI: 10.1007/s40123-025-01299-5 Diabetologia IF: 10.200Ahead of Print.No.07Glycaemic, appetite and circadian benefits of a dairy-enriched diet with high-protein breakfast and early daytime-restricted carbohydrate intake in type 2 diabetes: a randomised crossover trial富含奶制品的饮食搭配高蛋白早餐和日间早期限制碳水化合物摄入为2型糖尿病带来血糖、食欲和昼夜节律获益：一项随机交叉试验DOI: 10.1007/s00125-025-06658-2 British dental journal IF: 02.300Volume 240, Issue 2No.08Non-sugar sweeteners - too sweet to be true?非糖甜味剂——真的甜到好处吗？DOI: 10.1038/s41415-025-9252-8 Clinical therapeutics IF: 03.600Ahead of Print.No.09Study of Insulin Treatment Modalities in Adults With Cystic Fibrosis-Related Diabetes After Elexacaftor-Tezacaftor-Ivacaftor TherapyElexacaftor-Tezacaftor-Ivacaftor治疗后成人囊性纤维化相关糖尿病患者胰岛素治疗模式研究DOI: 10.1016/j.clinthera.2025.12.016 Pathology IF: 03.000Ahead of Print.No.10Screening for multiple myeloma has low yield as part of a secondary osteoporosis screen作为继发性骨质疏松症筛查的一部分，多发性骨髓瘤筛查的检出率较低DOI: 10.1016/j.pathol.2025.11.004 Evidence-based nursingAhead of Print.No.11Tailored, resource-aware implementation is crucial for sustainable diabetes prevention in primary care初级保健中可持续糖尿病预防的关键在于定制化且资源意识强的实施DOI: 10.1136/ebnurs-2025-104430 Advances in geneticsVolume 115, Issue No.12The JAK-STAT signaling pathway in inflammatory and autoimmune diseases: Its potential role as a therapeutic targetJAK-STAT信号通路在炎症与自身免疫性疾病中的作用及其作为治疗靶点的潜力DOI: 10.1016/bs.adgen.2025.11.008 Endocrinol Diabetes Nutr (Engl Ed) IF: 01.800Volume 73, Issue 1No.13Recent advances in pituitary tumors following the 2022 WHO classification2022年WHO分类发布后的垂体肿瘤研究新进展DOI: 10.1016/j.endien.2026.501747 Endocrinol Diabetes Nutr (Engl Ed) IF: 01.800Volume 73, Issue 1No.14Radioactive iodine-induced esophagitis: A rare complication放射性碘诱发的食管炎：一种罕见并发症DOI: 10.1016/j.endien.2025.501656 Endocrinol Diabetes Nutr (Engl Ed) IF: 01.800Volume 73, Issue 1No.15Vitamin K in home parenteral nutrition: Is it really necessary?家庭肠外营养中的维生素K：真的必要吗？DOI: 10.1016/j.endien.2025.501655 Endocrinol Diabetes Nutr (Engl Ed) IF: 01.800Volume 73, Issue 1No.16Enhancing levothyroxine dosing accuracy post-total thyroidectomy using body fat percentage利用体脂百分比提高全甲状腺切除术后左甲状腺素剂量准确性DOI: 10.1016/j.endien.2025.501645 J Stroke Cerebrovasc Dis IF: 01.800Ahead of Print.No.17Early Insights from a Multi-Centre National Stroke Surveillance Initiative in Tanzania坦桑尼亚多中心国家卒中监测倡议的早期发现DOI: 10.1016/j.jstrokecerebrovasdis.2026.108571 Toxicol Appl Pharmacol IF: 03.400Ahead of Print.No.18Sustained cadmium exposure and hyperglycemia additively drives mitochondrial dysfunction in hepatic cells: Implications for MASLD etiopathogenesis持续镉暴露与高血糖协同加剧肝细胞线粒体功能障碍：对MASLD发病机制的启示DOI: 10.1016/j.taap.2026.117729 Am J Clin Nutr IF: 06.900Ahead of Print.No.19Metabolome contribution to sex differences in the link between alcohol consumption and type 2 diabetes: a prospective analysis in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)代谢组对饮酒与2型糖尿病关联中性别差异的贡献：一项基于 Hispanic Community Health Study/Study of Latinos (HCHS/SOL)的前瞻性分析DOI: 10.1016/j.ajcnut.2026.101203 Clinical nutrition ESPEN IF: 02.600Ahead of Print.No.20Reply - Letter to the editor: Impact of fish oil-enriched high protein peptide-based formula on free fatty acid profiles and metabolomic changes in home enterally fed patients: A pilot study回复—致编辑的信：富含鱼油的高蛋白肽基配方对居家肠内营养患者游离脂肪酸谱及代谢组学变化的影响：一项初步研究DOI: 10.1016/j.clnesp.2026.102923 Clin Gastroenterol Hepatol IF: 12.000Ahead of Print.No.21Reply to : "Is baseline MASH fibrosis the key determinant for survival after bariatric surgery ?"回应：“基线MASH纤维化是减重手术后生存预后的关键决定因素吗？”DOI: 10.1016/j.cgh.2026.01.006 J Foot Ankle Surg IF: 01.300Ahead of Print.No.22Two-Dimensional vs Three-Dimensional Analysis of Weightbearing Charcot Neuropathy Deformities负重夏科氏神经关节病畸形的二维与三维分析对比DOI: 10.1053/j.jfas.2026.01.010 Environment international IF: 09.700Ahead of Print.No.23Longitudinal associations of long-term exposure to ambient air pollution, residential greenness, and air temperature with type 2 diabetes subphenotypes: Results from the KORA cohort study长期环境空气污染、住宅绿化及气温暴露与2型糖尿病亚型纵向关联研究：来自KORA队列研究的结果DOI: 10.1016/j.envint.2025.110043 Hormones and behavior IF: 02.400Ahead of Print.No.24Early androgens and development of social personality traits: Evidence from classical congenital adrenal hyperplasia早期雄激素与社交人格特质发展：来自经典先天性肾上腺增生症的证据DOI: 10.1016/j.yhbeh.2025.105875 Journal of pediatric nursing IF: 02.300Ahead of Print.No.25Adolescents' experiences of hypoglycemic episodes in type 1 diabetes青少年1型糖尿病患者的低血糖发作体验DOI: 10.1016/j.pedn.2026.01.023 Pediatric neurology IF: 02.100Ahead of Print.No.26The Relationship of Serum Uric Acid With Neurocognitive Functions in Children and Adolescents With Mild to Moderate Chronic Kidney Disease血清尿酸水平与轻度至中度慢性肾脏病儿童及青少年神经认知功能的关系DOI: 10.1016/j.pediatrneurol.2025.12.024 British journal of anaesthesia IF: 09.200Ahead of Print.No.27Perioperative management of patients taking glucagon-like peptide-1 receptor agonists: implementation of complex fasting recommendations. Response to Br J Anaesth 2025; 136: 375-6围手术期管理使用胰高血糖素样肽-1受体激动剂的患者：实施复杂禁食建议——对 Br J Anaesth 2025; 136: 375-6 的回应DOI: 10.1016/j.bja.2025.12.022 Fertility and sterility IF: 07.000Ahead of Print.No.28The Reproductive Tract Microbiome and Female Fertility: Dysbiosis, Disease Links, and Emerging Therapeutic Strategies生殖道微生物群与女性生育力：菌群失调、疾病关联及新兴治疗策略DOI: 10.1016/j.fertnstert.2026.01.010 Wiener klinische Wochenschrift IF: 02.100Ahead of Print.No.29Determination of the relationship between mothers' carbohydrate counting knowledge and glycemic control in children with type 1 diabetes母亲碳水化合物计数知识与儿童1型糖尿病血糖控制关系的研究DOI: 10.1007/s00508-025-02696-3 Placenta IF: 02.500Ahead of Print.No.30Structural alterations in the placental villous tree in well-controlled gestational diabetes mellitus控制良好的妊娠期糖尿病中胎盘绒毛树的结构改变DOI: 10.1016/j.placenta.2026.01.010 Comput Biol Chem IF: 03.100Ahead of Print.No.31Tailored pyrrole-based imidazothiazole scaffolds: Synthetic elaboration, enzyme kinetic profiling and DFT-guided molecular docking toward Antidiabetic therapeutics设计合成的吡咯基咪唑并噻二唑骨架：合成拓展、酶动力学分析及基于DFT的分子对接用于抗糖尿病治疗DOI: 10.1016/j.compbiolchem.2026.108920 Am J Vet Res IF: 01.400Ahead of Print.No.32Oral gabapentin reduces respiratory rate and resistance scores in adult domestic pigeons (Columba livia domestica) during and after handling口服加巴喷丁降低成年家鸽（Columba livia domestica）在操作期间及操作后的呼吸频率与抵抗评分DOI: 10.2460/ajvr.25.11.0401 J Gen Intern Med IF: 04.200Ahead of Print.No.33Gender Differences in Statin Discontinuation and Adherence Among Privately Insured People with HIV in the USA美国有私人保险的HIV感染者中他汀类药物停用与依从性的性别差异DOI: 10.1007/s11606-025-10164-x Res Social Adm Pharm IF: 02.800Ahead of Print.No.34Assessing the impact of frailty on statin prescriptions among older stroke survivors with and without diabetes评估虚弱对老年卒中幸存者他汀类处方的影响：糖尿病与非糖尿病患者的比较DOI: 10.1016/j.sapharm.2026.01.004 J Gen Intern Med IF: 04.200Ahead of Print.No.35Subtle Laboratory and Clinical Precursors of Celiac Disease in Young Adults: A Large-Scale Retrospective Cohort Study年轻成人乳糜泻的细微实验室与临床先兆：一项大规模回顾性队列研究DOI: 10.1007/s11606-026-10187-y BMC public health IF: 03.600Ahead of Print.No.36Evaluation of the experience of people referred under the NHS enhanced service incentive for obesity to the NHS digital weight management programme: a mixed method study对经NHS肥胖管理增强服务激励计划转诊至NHS数字体重管理项目者的体验评估：一项混合方法研究DOI: 10.1186/s12889-026-26203-z Canadian journal of anaesthesia IF: 03.300Ahead of Print.No.37Characteristics of the epidural electrical stimulation test and pressure waveform test to confirm epidural catheter placement in patients who are pregnant and have a body mass index higher than 50 kg·m(-2)体重指数高于50 kg·m(-2)孕妇中硬膜外电刺激测试与压力波形测试确认硬膜外导管放置的特征DOI: 10.1007/s12630-025-03062-7 The AAPS journal IF: 03.700Volume 28, Issue 2No.38Pharmacokinetics of Inhibitors of Succinyl-CoA:3-Ketoacid CoA Transferase in Sprague-Dawley Rats, and the Effect of a High-Fat DietSprague-Dawley大鼠中琥珀酰辅酶A：3-酮酸辅酶A转移酶抑制剂的药代动力学及高脂饮食的影响DOI: 10.1208/s12248-026-01208-z European journal of pediatrics IF: 02.600Volume 185, Issue 2No.39Influence of weight perception on the evolution of body composition of adolescents under obesity treatment体重感知对接受肥胖治疗的青少年身体成分演变的影响DOI: 10.1007/s00431-025-06737-x Surg Obes Relat Dis IF: 03.800Ahead of Print.No.40Left ventricular assist devices triple the risk of serious complications and longer hospital stay following bariatric surgery: a national analysis of 180,544 Metabolic and Bariatric Surgery Accreditation and Quality Improvement Program cases左心室辅助装置使减重术后严重并发症风险增加三倍，并延长住院时间：基于180,544例MBSAQIP病例的国家数据分析DOI: 10.1016/j.soard.2025.12.003 Endocrinol Diabetes Nutr (Engl Ed) IF: 01.800Volume 73, Issue 1No.41Beyond vectorial bioelectrical impedance: Assessing body composition changes with novel electrical parameters in obese osteoarthritis patients on a meal-replacement diet超越矢量生物电阻抗：利用新型电学参数评估肥胖骨关节炎患者进行代餐饮食后的身体成分变化DOI: 10.1016/j.endien.2025.501644 BMJ open IF: 02.300Volume 16, Issue 1No.42Evaluation of an innovative family-centred care and prevention intervention for children with overweight and obesity: a mixed-methods study protocol of the randomised controlled fruehstArt study in Germany德国fruehstArt随机对照研究：一项针对超重和肥胖儿童的创新性以家庭为中心的照护与预防干预的评估——一项混合方法研究方案DOI: 10.1136/bmjopen-2025-111373 Biochim Biophys Acta Gene Regul Mech IF: 03.100Ahead of Print.No.43Tet2-mediated Pref-1 activation delays adipocyte differentiationTet2介导的Pref-1激活延迟脂肪细胞分化DOI: 10.1016/j.bbagrm.2026.195137 Contraception IF: 02.300Ahead of Print.No.44Evaluating Graduating OBGYN Residents' Training in Postpartum Permanent Contraceptive Procedures评估即将毕业的妇产科住院医师产后永久避孕手术的培训情况DOI: 10.1016/j.contraception.2026.111372 Revista cli?nica espan?olaAhead of Print.No.45Position statement of the spanish society of internal medicine (SEMI) and the portuguese society of internal medicine (SPMI)西班牙内科医学会与葡萄牙内科医学会立场声明DOI: 10.1016/j.rceng.2026.502468 World neurosurgery IF: 02.100Ahead of Print.No.46Body Mass Index as A risk Factor for Recurrence and Frequency of Re-surgery After Lumbar Spine Surgery体重指数作为腰椎手术后复发及再手术频率的风险因素DOI: 10.1016/j.wneu.2026.124824 Journal of nutrition IF: 03.800Ahead of Print.No.47Integrative Nutrigenomics Approach in Polycystic Ovarian Syndrome: Targeting Gene-Diet Interactions for Personalized Nutraceutical Interventions多囊卵巢综合征的整合营养基因组学方法：靶向基因-饮食相互作用实现个性化营养干预DOI: 10.1016/j.tjnut.2026.101371 Journal of nutrition IF: 03.800Ahead of Print.No.48Chemical Analysis of Controlled Diets High in and Free of Ultra-processed Foods (UPF) and Proof-of-Concept Findings: Reducing UPF Consumption May Lower Diabetes Risk in Mid-life Adults高含量与零含量超加工食品的控制饮食化学分析及概念验证发现：减少超加工食品摄入或可降低中年成人糖尿病风险DOI: 10.1016/j.tjnut.2026.101370 Molecular metabolism IF: 06.600Ahead of Print.No.49α-Parvin Promotes Glucose Uptake and Metabolism in Skeletal Muscle with Minimal Influence on Hepatic Insulin Sensitivityα-Parvin促进骨骼肌葡萄糖摄取与代谢，对肝脏胰岛素敏感性影响甚微DOI: 10.1016/j.molmet.2026.102322 Cell reports IF: 06.900Ahead of Print.No.50Integrative multi-omics analysis reveals oral microbiome-metabolome signatures of obesity整合多组学分析揭示肥胖的口腔微生物组-代谢组特征DOI: 10.1016/j.celrep.2025.116819 Cell reports medicine IF: 10.600Ahead of Print.No.51Gut microbiome and obesity care: Bridging dietary, surgical, and pharmacological interventions肠道微生物组与肥胖管理：连接饮食、手术及药物干预DOI: 10.1016/j.xcrm.2025.102573 Gait & posture IF: 02.400Ahead of Print.No.52Cognitive decline outweighs adiposity in influencing lower limb gait kinematics in older adults在影响老年人下肢步态运动学方面，认知功能下降重于肥胖水平DOI: 10.1016/j.gaitpost.2026.110104 J Psychosom Res IF: 03.300Ahead of Print.No.53The association between sleep trajectories throughout pregnancy and postpartum pain in individuals with overweight or obesity: A prospective cohort study超重或肥胖个体孕期睡眠轨迹与产后疼痛的关联：一项前瞻性队列研究DOI: 10.1016/j.jpsychores.2026.112535 Geriatric nursing IF: 02.400Ahead of Print.No.54Association of routine clinical indicators for metabolic and cardiovascular health with weight loss in non-obese older adults: A case-control study using annual health screening data in Japan常规代谢与心血管健康指标与非肥胖老年人体重减轻的关联：基于日本年度健康筛查数据的病例对照研究DOI: 10.1016/j.gerinurse.2026.103889 BMC endocrine disorders IF: 03.300Ahead of Print.No.55Incidence and risk factors for osteoporosis in people with type 2 diabetes mellitus in Thailand泰国2型糖尿病患者骨质疏松症的发病率和危险因素DOI: 10.1186/s12902-026-02165-6 ?eská gynekologie IF: 00.500Volume 90, Issue 6No.56Status of a lipid accumulation product, triglycerides/ glucose index and visceral adiposity index on cardiometabolic risk factors in young polycystic ovary syndrome patients脂质蓄积产物、甘油三酯/葡萄糖指数与内脏肥胖指数在年轻多囊卵巢综合征患者心血管代谢风险因素中的状态评估DOI: 10.48095/cccg2025457 International dental journal IF: 03.700Ahead of Print.No.57Oral Health of Children With Severe or Complex Obesity and Association of Markers of Glucose Metabolism With Gingivitis重度或复杂性肥胖儿童的口腔健康及血糖代谢标志物与牙龈炎的相关性研究DOI: 10.1016/j.identj.2025.109383 Nature communications IF: 15.700Ahead of Print.No.58Epigenome-wide analysis identifies DNA methylation mediators of treatment-related cardiometabolic risk in survivors of childhood cancer表观基因组分析识别儿童癌症幸存者中治疗相关心血管代谢风险的DNA甲基化介导因子DOI: 10.1038/s41467-026-68689-6 Annals of hepatology IF: 04.400Ahead of Print.No.59Twofold increased risk of coronary artery disease after liver transplantation: A nationwide Swedish cohort of 2925 patients肝移植后冠心病风险增加两倍：瑞典全国性队列研究纳入2925例患者DOI: 10.1016/j.aohep.2025.102172 Value in health regional issues IF: 01.500Ahead of Print.No.60Retail Sales of Drugs for Diabetes, Dyslipidemia, and Hypertension in Chile Under 2 Health Policies2种健康政策下智利糖尿病、血脂异常和高血压药物的零售销售DOI: 10.1016/j.vhri.2025.101577 Neurochemical research IF: 03.800Volume 51, Issue 1No.61Metformin Ameliorates Cognitive Deficits and Neuroinflammation in a Mouse Model of Familial Hypercholesterolemia二甲双胍改善家族性高胆固醇血症小鼠模型的认知缺陷和神经炎症DOI: 10.1007/s11064-025-04658-7 European neuropsychopharmacology IF: 06.700Ahead of Print.No.62Antipsychotic plasma concentration as predictor of movement disorders and cardiometabolic side-effects: A comparison with prescription dose抗精神病药物血浆浓度作为运动障碍和心血管代谢副作用的预测因子：与处方剂量的比较DOI: 10.1016/j.euroneuro.2026.112769 Journal of clinical neuroscience IF: 01.800Ahead of Print.No.63Neuromuscular ultrasound and nerve conduction studies as complementary tools for screening of diabetic peripheral neuropathy神经肌肉超声与神经传导研究作为糖尿病周围神经病变筛查的互补工具DOI: 10.1016/j.jocn.2026.111876 CPT Pharmacometrics Syst Pharmacol IF: 03.000Volume 15, Issue 2No.64Preclinical Modeling and Simulation to Explore the Tissue/Plasma Exposure and Pharmacodynamic Effect of Vildagliptin in Diabetes Treatment临床前建模与模拟探索维格列汀在糖尿病治疗中的组织/血浆暴露及药效学效应DOI: 10.1002/psp4.70165 British journal of pharmacology IF: 07.700Ahead of Print.No.65Glucagon-like peptide-1 receptor agonists and muscle strength changes in older adults: Risks beyond muscle mass reductions胰高血糖素样肽-1受体激动剂与老年人肌力变化：超越肌肉量减少的风险DOI: 10.1111/bph.70355 Journal of neurosurgery. Spine IF: 03.100Ahead of Print.No.66The comparative impact of body mass index on outcomes following minimally invasive versus open surgery for grade 1 spondylolisthesis: 2-year follow-up from the Quality Outcomes Database体重指数对微创与开放手术治疗1级腰椎滑脱疗效的比较性影响：基于质量结局数据库的2年随访DOI: 10.3171/2025.9.SPINE25552 Lab on a chip IF: 05.400Ahead of Print.No.67Online affinity micro free-flow electrophoresis for the continuous monitoring of insulin via a competitive immunoassay基于竞争性免疫分析的在线亲和微自由流电泳技术用于胰岛素连续监测DOI: 10.1039/d5lc00745c PloS one IF: 02.600Volume 21, Issue 1No.68Evaluation of rat pancreatic islets damage after siRNA microporationsiRNA微穿孔后大鼠胰腺胰岛的损伤评估DOI: 10.1371/journal.pone.0340066 Biomaterials IF: 12.900Ahead of Print.No.69Smart multifunctional ROS-responsive supramolecular hydrogel for simultaneously regulating oxidative stress, immune dysregulation, and bacterial infection in diabetic wound healing智能多功能ROS响应性超分子水凝胶同步调控糖尿病伤口愈合中的氧化应激、免疫失调和细菌感染DOI: 10.1016/j.biomaterials.2026.124006 Journal of neurosurgery IF: 03.600Ahead of Print.No.70Association of standard postoperative day 1 discharge following endonasal surgery for pituitary adenoma with lower complication rates and unplanned medical care垂体腺瘤经鼻手术后标准术后第1天出院与较低并发症率及未计划医疗照护相关DOI: 10.3171/2025.9.JNS25752 Journal of clinical oncology : IF: 41.900Ahead of Print.No.71Threshold Dose-Response Association Between Alcohol Consumption and Risk of Young-Onset Pancreatic Cancer: A Nationwide Korean Cohort Study of Young Adults Age 20-39 Years酒精消费与年轻发病胰腺癌风险的阈值剂量反应关联：一项针对韩国20-39岁年轻成人的全国性队列研究DOI: 10.1200/JCO-25-01169 Science advances IF: 12.500Volume 12, Issue 4No.72Neuronal GPR75 deficiency protects against diet-induced obesity in a humanized mouse model在人源化小鼠模型中，神经元GPR75缺陷可预防饮食诱导的肥胖DOI: 10.1126/sciadv.ady7993 Science advances IF: 12.500Volume 12, Issue 4No.73CD318 expression defines a novel subset of human CD8(+) regulatory T cellsCD318的表达定义了人类CD8(+)调节性T细胞的一个新亚群DOI: 10.1126/sciadv.adz4203 Science advances IF: 12.500Volume 12, Issue 4No.74TDRD3, a Tudor domain-containing protein, regulates Klf2-dependent T(reg) differentiation and function to modulate immune tolerance含有Tudor结构域的蛋白TDRD3通过调控Klf2依赖性Treg分化与功能调节免疫耐受DOI: 10.1126/sciadv.aea3960 PloS one IF: 02.600Volume 21, Issue 1No.75The role of obesity and Type 2 diabetes in lung health: A systematic review (2024)肥胖与2型糖尿病在肺健康中的作用：一项系统综述DOI: 10.1371/journal.pone.0340692 PloS one IF: 02.600Volume 21, Issue 1No.76Cardiovascular risk among middle-aged Japanese adults with atopic dermatitis: A nested case-control study日本中年特应性皮炎患者的心血管风险：一项巢式病例对照研究DOI: 10.1371/journal.pone.0341337 PloS one IF: 02.600Volume 21, Issue 1No.77Stress hyperglycemia ratio predicts adverse outcomes in emergency department patients with upper gastrointestinal bleeding应激性高血糖比值预测急诊上消化道出血患者不良结局DOI: 10.1371/journal.pone.0340450 PloS one IF: 02.600Volume 21, Issue 1No.78Pharmacological evaluation of mangrove plant Rhizophora mucronata (Lam.) grown in the coastal area of Sundarbans对生长在孙德尔本斯沿海地区的红树植物红茄苳（Rhizophora mucronata (Lam.)）的药理评价DOI: 10.1371/journal.pone.0340646 PloS one IF: 02.600Volume 21, Issue 1No.79Impact of cardiometabolic risk factors on hepatocellular carcinoma incidence in patients with chronic hepatitis B: A retrospective cohort study心脏代谢风险因素对慢性乙型肝炎患者肝细胞癌发病的影响：一项回顾性队列研究DOI: 10.1371/journal.pone.0341366 PloS one IF: 02.600Volume 21, Issue 1No.80Developing count regression techniques for predicting the number of new type 2 diabetes cases in Saudi Arabia开发计数回归技术预测沙特阿拉伯2型糖尿病新发病例数DOI: 10.1371/journal.pone.0341436 JMIR research protocols IF: 01.500Volume 15, Issue No.81Developing a Culturally Adapted Digital Health Application for Older Hispanic Adults With Type 2 Diabetes: Protocol for a Qualitative and Pilot Study为患有2型糖尿病的老年西班牙裔成年人开发文化适应性数字健康应用程序：一项定性和试点研究方案DOI: 10.2196/76294 Med Lett Drugs Ther IF: 01.400Volume 67, Issue 1743No.82Comparison chart: Some available insulins for type 2 diabetes对比图表：2型糖尿病部分可用胰岛素DOI: 10.58347/tml.2025.1743d Med Lett Drugs Ther IF: 01.400Volume 67, Issue 1743No.83Insulins for type 2 diabetes2型糖尿病胰岛素疗法概览DOI: 10.58347/tml.2025.1743c Med Lett Drugs Ther IF: 01.400Volume 67, Issue 1743No.84A cardiovascular indication for oral semaglutide (Rybelsus)口服司美格鲁肽(Rybelsus)的心血管适应症DOI: 10.58347/tml.2025.1743b PloS one IF: 02.600Volume 21, Issue 1No.85HbA1c underperforms in identifying abnormal glucose tolerance in the presence of G6PD deficiency: Insight from the Africans in America study在G6PD缺乏症背景下，HbA1c识别糖耐量异常的效能降低：来自“美国非洲裔人群”研究的见解DOI: 10.1371/journal.pone.0334634 Med Lett Drugs Ther IF: 01.400Volume 68, Issue 1747No.86Risks of tramadol and gabapentin use for pain曲马多与加巴喷丁用于疼痛的风险DOI: 10.58347/tml.2026.1747d Appl Biochem Biotechnol IF: 03.300Ahead of Print.No.87Modulatory Role of Moringa Oleifera-Loaded Silver Nanoparticles on UCP1 and PPARGC1A Genes Expression in an Obesity Rat Model辣木负载银纳米颗粒在肥胖大鼠模型中对UCP1和PPARGC1A基因表达的调节作用DOI: 10.1007/s12010-025-05511-x Pediatric nephrology IF: 02.600Ahead of Print.No.88Beyond genetics: how environmental stressors drive pediatric hypertension risk超越遗传学：环境压力因素如何驱动儿童高血压风险DOI: 10.1007/s00467-025-07145-x J Nutr Educ Behav IF: 02.300Ahead of Print.No.89Stakeholder Perspectives on Remote Delivery of a Group-Based Child Obesity Prevention Program for Latino Families With Low Income利益相关者对拉丁裔低收入家庭基于群体的儿童肥胖预防项目远程实施的看法DOI: 10.1016/j.jneb.2025.12.004 Immunological reviews IF: 08.300Volume 338, Issue 1No.90Sex Differences in the Impact of Obesity on Immunity肥胖对免疫影响中的性别差异DOI: 10.1111/imr.70101 Cancer science IF: 04.300Ahead of Print.No.91Effect Modification by Cofactors in the Impact of Body Mass Index Change on the Risk of Lung Cancer体重指数变化对肺癌风险的影响：多种因素的效应修饰作用DOI: 10.1111/cas.70332 Die Chirurgie IF: 00.600Ahead of Print.No.92[Oral intake of 25 mg semaglutide in adults with overweight or obesity]超重或肥胖成人中口服25毫克司美格鲁肽DOI: 10.1007/s00104-026-02452-x Clin Transl Oncol IF: 02.500Ahead of Print.No.93IRS2 as a driver and therapeutic target in brain metastases from colorectal cancer: a systematic review of mechanistic and translational evidenceIRS2作为结直肠癌脑转移的驱动因子和治疗靶点：机制与转化证据的系统综述DOI: 10.1007/s12094-025-04212-5 Arch Gynecol Obstet IF: 02.500Volume 313, Issue 1No.94Impact of hormones on lipedema development: a systematic literature review激素对脂肪水肿发展的影响：一项系统性文献综述DOI: 10.1007/s00404-026-08318-1 Macromolecular bioscience IF: 04.100Volume 26, Issue 1No.95Identification of Novel Growth Factor Conjugated Nanofibers for Stimulation of Neuronal Growth鉴定用于刺激神经元生长的生长因子共轭纳米纤维DOI: 10.1002/mabi.202500585 J Int Med Res IF: 01.500Volume 54, Issue 1No.96Relationship of body composition with cortisol and dehydroepiandrosterone sulfate levels in Korean men and women韩国成年男女身体成分与皮质醇及脱氢表雄酮硫酸盐水平的关系DOI: 10.1177/03000605251413389 Med Lett Drugs Ther IF: 01.400Volume 68, Issue 1747No.97Oral semaglutide (Wegovy) for weight loss口服司美格鲁肽（Wegovy）用于减重DOI: 10.58347/tml.2026.1747a La Revue du praticienVolume 75, Issue 9No.98[Why and how should the renal risk of patients with type 2 diabetes be assessed ?]为何及如何评估2型糖尿病患者的肾脏风险https://pubmed.ncbi.nlm.nih.gov/41575136 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.99SGLT2 inhibitors and mortality in older adults with diabetic kidney disease: A target trial emulation studySGLT2抑制剂与老年糖尿病肾病患者死亡率：一项靶向试验仿真研究DOI: 10.1111/dom.70502 JAMA IF: 55.000Ahead of Print.No.100Higher Food Preservative Intake Linked With Type 2 Diabetes食物防腐剂摄入量增加与2型糖尿病相关DOI: 10.1001/jama.2025.23033 JAMA Network Open IF: 09.700Volume 9, Issue 1No.101Voice Assistant for Older Adults With Type 2 Diabetes面向2型糖尿病老年患者的语音助手DOI: 10.1001/jamanetworkopen.2025.53483 Eur J Clin Microbiol Infect Dis IF: 03.000Ahead of Print.No.102Epidemiological profile and clinical outcomes of patients with mucormycosis: the multicenter retromucor study from Türkiye (2004-2024)毛霉菌病患者的流行病学特征与临床结局：土耳其多中心retromucor研究（2004-2024）DOI: 10.1007/s10096-025-05397-x Current obesity reports IF: 11.000Volume 15, Issue 1No.103Gut Peptide Alterations in Type 2 Diabetes and Obesity: A Narrative Review肠道肽在2型糖尿病与肥胖中的改变：叙事综述DOI: 10.1007/s13679-026-00687-7 J Physiol Biochem IF: 04.300Volume 82, Issue 1No.104Procyanidin B2 and an autochthonous apple pulp extract modulate oxidative stress and PPARγ expression on an in vitro model of lipid steatosis in HepG2 cells原花青素B2与一种本土苹果果肉提取物在HepG2细胞脂质变性体外模型中调节氧化应激与PPARγ表达DOI: 10.1007/s13105-026-01151-9 Diabetes Technol Ther IF: 06.300Ahead of Print.No.105Safety of Inhaled Insulin in Adults with Diabetes吸入胰岛素在成人糖尿病患者中的安全性DOI: 10.1177/15209156251390830 Kidney360 IF: 03.000Ahead of Print.No.106Clinical Characteristics and Disease Progression Among Non-Diabetic APOL1-Mediated Kidney Disease Patients and Patients with Other CKD非糖尿病APOL1介导的肾脏病患者与其他慢性肾脏病患者的临床特征及疾病进展比较DOI: 10.34067/KID.0000001097 JACC: Clinical Electrophysiology IF: 07.700Ahead of Print.No.107Transcatheter Tricuspid Valve Replacement in Patients With Cardiac Implantable Electronic Device Leads: The TRIPLACE Registry在伴心脏植入式电子装置导线的患者中行经导管三尖瓣置换术：TRIPLACE注册研究DOI: 10.1016/j.jacep.2025.12.027 Diabetes care IF: 16.600Ahead of Print.No.108The Look AHEAD Research Program: A 25-Year Retrospective From the Perspective of GeroscienceLook AHEAD研究项目：基于老年科学视角的25年回顾DOI: 10.2337/dci25-0126 Diabetes care IF: 16.600Ahead of Print.No.109Interlaboratory Evaluation of Multiplex Autoantibody Assay Performance in the Islet Autoantibody Standardization Program 2024 Workshop胰岛自身抗体标准化程序2024研讨会：多重自身抗体检测性能的室间评估DOI: 10.2337/dc25-1326 Reproduction IF: 03.700Ahead of Print.No.110Curating Fertility-Proteomic Remodelling of Sperm During Epididymal Transit塑造生育力：精子在附睾转运中的蛋白质组重塑DOI: 10.1093/reprod/xaag012 Organic letters IF: 05.000Ahead of Print.No.111Total Synthesis of Okeaniamide AOkeaniamide A的全合成DOI: 10.1021/acs.orglett.5c05432 Annals of African medicine IF: 00.600Ahead of Print.No.112Management of Chronic Pancreatitis with Pancreatic Duct Calculi伴有胰管结石的慢性胰腺炎的治疗DOI: 10.4103/aam.aam_654_25 La Revue du praticienVolume 75, Issue 9No.113[What are the key takeaways from the HAS recommendations regarding special populations (elderly populations and pregnancy or planning to become pregnant) ?]关于特殊人群（老年人群、孕产妇或备孕者），法国国家卫生管理局（HAS）建议的要点是什么？https://pubmed.ncbi.nlm.nih.gov/41575137 La Revue du praticienVolume 75, Issue 9No.114[Lifestyle modifications in type 2 diabetes: yes, but how ?]2型糖尿病的生活方式干预：方向明确，如何落实？https://pubmed.ncbi.nlm.nih.gov/41575134 La Revue du praticienVolume 75, Issue 9No.115[From glycemic control to comprehensive management of patients living with type 2 diabetes: a paradigm shift ?]从血糖控制到2型糖尿病患者的综合管理：一场范式转变https://pubmed.ncbi.nlm.nih.gov/41575132 MS. Me?decine sciences IF: 00.400Volume 42, Issue 1No.116[Intestinal microbiota biodiversity and the modern diet: consequences for human health]肠道微生物群多样性与现代饮食：对人类健康的影响DOI: 10.1051/medsci/2025253 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.117Efficacy and safety of once-weekly insulins in type 2 diabetes: A systematic review and meta-analysis一周一次胰岛素在2型糖尿病中的有效性与安全性：一项系统评价与Meta分析DOI: 10.1111/dom.70497 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.118Lorcaserin induces abdominal fat loss with associated improvements of the circulating metabolome/lipidome and no changes in the myostatin-activin-follistatin-IGF-1 axes: A 6-month long randomized placebo-controlled clinical trial氯卡色林通过改善循环代谢组/脂质组谱诱导腹部脂肪减少，且不改变肌肉生长抑制素-激活素-卵泡抑素-IGF-1轴：一项为期6个月的随机安慰剂对照临床试验DOI: 10.1111/dom.70496 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.119Methylglyoxal-derived hydroimidazolone (MG-H1) is a novel marker of insulin resistance in Japanese individuals, disturbing insulin signalling via mTORC2 in cultured myocytes甲基乙二醛衍生的氢咪唑酮(MG-H1)是日本人群胰岛素抵抗的新标志物，通过mTORC2干扰培养肌细胞的胰岛素信号DOI: 10.1111/dom.70489 Health promotion practice IF: 01.200Ahead of Print.No.120Evaluation of a Prediabetes Media Campaign for Black and Hispanic Men to Increase Awareness of Diabetes Prevention and Address Health Inequity一项针对黑人和西班牙裔男性的糖尿病前期媒体运动评估：旨在提高糖尿病预防意识并解决健康不平等问题DOI: 10.1177/15248399251414653 Acta Cardiologica IF: 02.500Ahead of Print.No.121Incidence, risk factors and prognostic impact of cerebrovascular events after transcatheter aortic valve implantation经导管主动脉瓣植入术后脑血管事件的发生率、风险因素及预后影响DOI: 10.1080/00015385.2026.2617492 American journal of epidemiology IF: 04.800Ahead of Print.No.122Thyroid autoimmunity and the subsequent development of islet and celiac autoimmunity in the TEDDY study甲状腺自身免疫与后续胰岛及乳糜泻自身免疫的发展：TEDDY研究DOI: 10.1093/aje/kwag016 Annals of African medicine IF: 00.600Ahead of Print.No.123Stem Cell Therapy as a Regenerative Strategy in Hereditary Pancreatitis Postpancreatectomy干细胞疗法作为遗传性胰腺炎胰腺切除术后的再生策略DOI: 10.4103/aam.aam_509_25 J Diabetes Investig IF: 03.000Ahead of Print.No.124Erythrocyte deformability correlates with microvascular ischemia and disease severity in diabetic retinopathy红细胞变形能力与糖尿病视网膜病变的微血管缺血和疾病严重程度相关DOI: 10.1111/jdi.70247 J Diabetes Investig IF: 03.000Ahead of Print.No.125A pitfall in diagnosing type B insulin resistance syndrome: Suspected antibody interference in a patient with insulin allergy诊断B型胰岛素抵抗综合征的一个陷阱：胰岛素过敏患者中的疑似抗体干扰DOI: 10.1111/jdi.70235 J Diabetes Investig IF: 03.000Ahead of Print.No.126Increased C-reactive protein is associated with corneal nerve loss and painful neuropathic symptoms in Type 2 diabetes mellitusC反应蛋白升高与2型糖尿病患者角膜神经损失及疼痛性神经病变症状相关DOI: 10.1111/jdi.70246 Eur J Neurosci IF: 02.400Volume 63, Issue 2No.127Electrical Synapses Contribute to Sleep-Dependent Declarative Memory Retention电突触促进睡眠依赖性陈述性记忆保留DOI: 10.1111/ejn.70401 Pol Arch Intern Med IF: 04.700Ahead of Print.No.128Determining the association between preeclampsia and the thyroid hormone status in pregnant women with type 1 diabetes探究1型糖尿病孕妇先兆子痫与甲状腺激素状态的关联性DOI: 10.20452/pamw.17199 International wound journal IF: 02.500Volume 23, Issue 1No.129A Prospective Randomised Clinical Study Comparing Polygalacturonic and Caprylic Acid Ointment to Medical-Grade Honey in the Management of Chronic Wounds比较聚半乳糖醛酸-辛酸软膏与医用级蜂蜜治疗慢性伤口的前瞻性随机临床研究DOI: 10.1111/iwj.70815 JCI insight IF: 06.100Volume 11, Issue 2No.130Anti-CD3 mAb treatment reshapes infiltrating T and β cells in the islets in autoimmune diabetes抗CD3单抗治疗重塑自身免疫性糖尿病胰岛中的浸润性T细胞与β细胞DOI: 10.1172/jci.insight.192755 La Revue du praticienVolume 75, Issue 8No.131[Management of neuropathic pain: Don't lose hope!]神经病理性疼痛的管理：不要失去希望https://pubmed.ncbi.nlm.nih.gov/41575077 La Revue du praticienVolume 75, Issue 9No.132[Pharmacological management of non-insulin-treated type 2 diabetes: practical implementation of HAS guidelines]非胰岛素治疗的2型糖尿病的药物治疗：法国国家卫生管理局指南的实践实施https://pubmed.ncbi.nlm.nih.gov/41575133 Science progress IF: 02.900Volume 109, Issue 1No.133Retraction: Potassium bromate-induced nephrotoxicity and potential curative role of metformin loaded on gold nanoparticles撤稿：溴酸钾诱导的肾毒性及负载于金纳米颗粒的甲福明潜在治疗作用DOI: 10.1177/00368504261417035 Annals of African medicine IF: 00.600Ahead of Print.No.134Evaluating Antenatal Depression in Women with Gestational Diabetes Mellitus: A Hospital-based Observational Study妊娠期糖尿病女性产前抑郁评估：一项医院为基础的观察性研究DOI: 10.4103/aam.aam_700_25 La Revue du praticienVolume 75, Issue 9No.135[Why and how should the cardiovascular risk of patients with type 2 diabetes be assessed ?]为何以及如何评估2型糖尿病患者的心血管风险？https://pubmed.ncbi.nlm.nih.gov/41575135 Cancer Epidemiol Biomarkers Prev IF: 03.400Ahead of Print.No.136The Potential Impact of Histamine-2 Receptor Antagonists on Gynecologic Cancer Risk: A Population-Based Study of 23 Million IndividualsH2受体拮抗剂对妇科癌症风险的潜在影响：一项基于2300万人的群体研究DOI: 10.1158/1055-9965.EPI-25-1306 JACC: AdvancesVolume 5, Issue 2No.137FDA Cardiovascular Indication Expansion and Dispensing of Semaglutide/Tirzepatide in CVD Patients With Overweight/ObesityFDA心血管适应症扩展及司美格鲁肽/替尔泊肽在心血管疾病合并超重/肥胖患者中的处方情况DOI: 10.1016/j.jacadv.2025.102575 JACC: AdvancesVolume 5, Issue 2No.138Wireless Movement Activity and Cardiometabolic Disease Risk in Historical Redlined Areas历史红线划定区域内的无线移动活动与心血管代谢疾病风险DOI: 10.1016/j.jacadv.2025.102528 EBioMedicine IF: 10.800Volume 124, Issue No.139Endocrine and metabolic determinants of cardiometabolic risk in mild autonomous cortisol secretion轻度自主皮质醇分泌患者心脏代谢风险的内分泌和代谢决定因素DOI: 10.1016/j.ebiom.2026.106126 CNS Neurol Disord Drug Targets IF: 03.000Ahead of Print.No.140Investigation of the Antiepileptic and Anti-inflammatory Effects of Empagliflozin on Penicillin-induced Epileptiform Activity in Rats恩格列净对青霉素诱发大鼠癫痫样活动的抗癫痫及抗炎作用研究DOI: 10.2174/0118715273423680251125073602 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.141Diabetes and tumor risk: a 23-year Danish national cohort study糖尿病与肿瘤风险：一项为期23年的丹麦全国队列研究DOI: 10.3389/fendo.2025.1725065 Frontiers in nutrition IF: 05.100Volume 12, Issue No.142Editorial: The role of vitamin D in metabolic and cardiovascular health, volume II社论：维生素D在代谢和心血管健康中的作用（第二卷）DOI: 10.3389/fnut.2025.1759053 Diabetes Technol Ther IF: 06.300Ahead of Print.No.143Response to Comment on: "Nocturnal Hypoglycemia: Characterization with Continuous Glucose Monitoring in a Real-World Setting"对“夜间低血糖：真实世界环境中连续葡萄糖监测特征分析”评论的回应DOI: 10.1177/15209156251412814 Diabetes Technol Ther IF: 06.300Ahead of Print.No.144Hybrid Closed-Loop Disconnection Reduces the Risk of Hypoglycemia in Active Children and Adolescents with Type 1 Diabetes: A Randomized Controlled Pilot Study混合闭环系统断开可降低活跃1型糖尿病儿童及青少年的低血糖风险：一项随机对照试验DOI: 10.1177/15209156251390825 Eur J Endocrinol IF: 05.200Ahead of Print.No.145Long-Term Cardiac Effects of Adrenalectomy Versus Surveillance in Mild Cortisol Excess: 5-Year Results from the prospective ITACA Study轻度皮质醇过量中肾上腺切除术与监测的长期心脏效应：前瞻性ITACA研究的5年结果DOI: 10.1093/ejendo/lvag018 Current medicinal chemistry IF: 03.500Ahead of Print.No.146Differences of Plasma Metabolites in Sarcopenia Among Individuals with Type 2 Diabetes: A Cross-Sectional Study2型糖尿病患者肌少症的血浆代谢物差异：一项横断面研究DOI: 10.2174/0109298673417152251129140654 Endocrinol Diabetes Metab IF: 02.600Volume 9, Issue 1No.147Socioeconomic Inequalities and Type 2 Diabetes Comorbidities: A Systematic Review and Meta-Analysis on Observational Studies社会经济不平等与2型糖尿病合并症：一项基于观察性研究的系统评价与Meta分析DOI: 10.1002/edm2.70160 Sociology of health & illness IF: 02.700Volume 48, Issue 2No.148Transformations in Diabetes Care: Lessons From Commons-Based, Peer-Produced Citizen Science糖尿病护理的变革：来自基于公地、同伴生产的公民科学的启示DOI: 10.1111/1467-9566.70140 Med Sci Sports Exerc IF: 03.900Ahead of Print.No.149Stem Cell Transplant Patients' Activity Decline, Outpatient Resumption and Intervention Effectiveness Identified by Wearable Activity Monitoring通过可穿戴活动监测识别干细胞移植患者的活动下降、门诊恢复及干预效果DOI: 10.1249/MSS.0000000000003941 Transplantation IF: 05.000Ahead of Print.No.150Improving Bone Health in Type 1 Diabetes and Chronic Kidney Disease: The Overlooked Benefit of Simultaneous Pancreas-Kidney Transplantation改善1型糖尿病和慢性肾脏病中的骨骼健康：同步胰肾移植的被忽视的益处DOI: 10.1097/TP.0000000000005631 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.151Editorial: Applications of optical coherence tomography angiography (OCTA) in ocular complications of diabetes mellitus光学相干断层扫描血管成像（OCTA）在糖尿病眼部并发症中的应用DOI: 10.3389/fendo.2025.1743554 Drug delivery IF: 08.100Volume 33, Issue 1No.152Advancements and challenges in ophthalmic microneedles to treat eye diseases眼科微针在治疗眼部疾病中的进展与挑战DOI: 10.1080/10717544.2026.2617688 Molecular pharmaceutics IF: 04.500Ahead of Print.No.153Molecular Mechanisms of Liraglutide Aggregation Induced by Dual Air-Water and Silicone-Oil-Water Interfacial Stress空气-水与硅油-水双重界面应力诱导利拉鲁肽聚集的分子机制DOI: 10.1021/acs.molpharmaceut.5c01837 Bioeng Transl Med IF: 05.700Volume 11, Issue 1No.154Injectable hyaluronic acid-metformin conjugate gel for sustained intra-articular delivery and prevention of post-traumatic osteoarthritis可注射透明质酸-二甲双胍共轭凝胶用于关节内持续给药及创伤后骨关节炎的预防DOI: 10.1002/btm2.70100 Frontiers in psychiatry IF: 03.200Volume 16, Issue No.155Case Report: Persistent delusional memories after postoperative delirium in a woman with complex cardiac surgical history病例报告：一例具有复杂心脏手术史女性术后谵妄后的持久妄想性记忆DOI: 10.3389/fpsyt.2025.1743329 bioRxivVolume 2026, Issue No.156Lifespan-extending downregulation of insulin signalling reduces germline mutation load延长寿命的胰岛素信号下调可降低生殖细胞突变负荷DOI: 10.64898/2025.12.05.692572 bioRxivVolume 2026, Issue No.157A Fourfold Male-Specific Lifespan Extension via Canonical Insulin/IGF-1 Signaling经由经典胰岛素/IGF-1信号通路实现的雄性特异性四倍寿命延长DOI: 10.64898/2025.12.02.691904 bioRxivVolume 2026, Issue No.158AKT signaling in hepatocytes rapidly increases glucose phosphorylation and contribution to glycogen without affecting metabolite pool sizes or glycogen breakdown肝细胞中AKT信号快速增加葡萄糖磷酸化及向糖原的贡献，而不影响代谢物池大小或糖原分解DOI: 10.64898/2025.12.01.691331 bioRxivVolume 2026, Issue No.159Insular cortex predictions regulate glucose homeostasis岛叶皮层的预测调控葡萄糖稳态DOI: 10.64898/2025.12.09.693191 Curēus IF: 01.300Volume 17, Issue 12No.160Atypical Presentation and Unexpected Resolution: The Role of Serial Cerebrospinal Fluid Analysis in Differentiating Bacterial and Viral Meningitis After Pituitary Surgery垂体术后脑膜炎的不典型表现与转归：系列脑脊液分析在鉴别细菌性与病毒性感染中的关键作用DOI: 10.7759/cureus.99802 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.161Stc2a inhibits IGF-stimulated somatic growth in favor of organismal survival under hypoxic stressStc2a在低氧应激下抑制IGF介导的体细胞生长以利于机体存活DOI: 10.3389/fendo.2025.1729649 Pediatric diabetes IF: 05.600Volume 2026, Issue No.162Maternal Autoimmune Disease and Childhood-Onset Type 1 Diabetes: A Nationwide Population-Based Nested Case-Control Study母体自身免疫病与儿童期发病的1型糖尿病：一项全国性人群巢式病例对照研究DOI: 10.1155/pedi/3418021 Mol Nutr Food Res IF: 04.200Volume 70, Issue 2No.163A Comparative Study on the Effect of Omega-3 Fatty Acids on Lactationω-3脂肪酸对哺乳期影响的比较研究DOI: 10.1002/mnfr.70393 Epigenomics IF: 02.600Ahead of Print.No.164Paternal preconception exercise and sperm epigenetic mechanisms: a systematic review on offspring health父亲孕前运动与精子表观遗传机制：关于后代健康的系统综述DOI: 10.1080/17501911.2026.2620390 Current pharmaceutical design IF: 02.800Ahead of Print.No.165Gut Microbiota in the Hepato-Cardiorenal Axis: Microbial Metabolites, Inflammation, and Emerging Therapeutic Targets肝心肾轴中的肠道微生物群：微生物代谢产物、炎症与新兴治疗靶点DOI: 10.2174/0113816128413464251209115653 Cell transplantation IF: 03.200Volume 35, Issue No.166Editorial: Cellular replacement therapy for diabetes社论：糖尿病细胞替代疗法DOI: 10.1177/09636897251392313 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.167CGM-derived efficacy and overall safety of once-weekly insulin efsitora alfa (efsitora) relative to day of administration in adults with type 2 diabetes连续血糖监测评估的每周一次胰岛素efsitora alfa（efsitora）在2型糖尿病成人患者中的有效性和总体安全性：与给药日相关DOI: 10.1111/dom.70419 Molecular pharmaceutics IF: 04.500Ahead of Print.No.168Soluble Antigen Array Displaying Proinsulin(F25D) Selectively Targets Anti-insulin B Cells without Hormonal Effects展示前胰岛素(F25D)突变体的可溶性抗原阵列选择性靶向抗胰岛素B细胞且无激素效应DOI: 10.1021/acs.molpharmaceut.5c01428 Med Sci Sports Exerc IF: 03.900Ahead of Print.No.169Metabolic Effects of Isoenergetic High Intensity Interval Training and Moderate Intensity Continuous Training in Adults with Type I Diabetes等能量高强度间歇训练与中等强度持续训练对1型糖尿病成人的代谢影响DOI: 10.1249/MSS.0000000000003939 FCVM IF: 02.900Volume 12, Issue No.170Effects of fasting on endothelial function in type 2 diabetes mellitus patients: cohort study斋月禁食对2型糖尿病患者内皮功能的影响：一项队列研究DOI: 10.3389/fcvm.2025.1646786 Curēus IF: 01.300Volume 17, Issue 12No.171Unilateral Ptosis and Bulbar Symptoms as the Initial Presentation of Late-Onset Acetylcholine Receptor Antibody-Positive Myasthenia Gravis Mimicking Acute Ischemic Stroke in an 82-Year-Old Man单侧眼睑下垂与球部症状：一例82岁男性晚发性乙酰胆碱受体抗体阳性重症肌无力模仿急性缺血性卒中的初始表现DOI: 10.7759/cureus.99832 Current diabetes reviews IF: 01.900Ahead of Print.No.172The Beneficial Effects of Combination Therapy With SGLT-2 Inhibitors and GLP-1 Receptor Agonists in Type 2 Diabetes MellitusSGLT-2抑制剂与GLP-1受体激动剂联合治疗对2型糖尿病的有益效应DOI: 10.2174/0115733998419380251126073540 Endocr Metab Immune Disord Drug Targets IF: 02.000Ahead of Print.No.173Insight into Molecular Mechanisms and Pathways Related to the Association of Periodontal Disease and Type 2 Diabetes Mellitus牙周病与2型糖尿病关联的分子机制与通路研究进展DOI: 10.2174/0118715303415067251124044844 Scand J Rheumatol IF: 02.100Ahead of Print.No.174Organ-specific autoimmunity in primary Sjögren's disease原发性干燥综合征中的器官特异性自身免疫DOI: 10.1080/03009742.2025.2598989 Current pharmaceutical design IF: 02.800Ahead of Print.No.175Histone Acetylation Retards the Adipogenic Differentiation of Human Umbilical Cord - Mesenchymal Stem Cells: A Clue for Anti-obesity Approach?组蛋白乙酰化延缓人脐带间充质干细胞的成脂分化：抗肥胖方法的一条线索？DOI: 10.2174/0113816128396945251127151448 Mol Nutr Food Res IF: 04.200Volume 70, Issue 2No.176Wheat Flour Intake Promotes Weight Gain and Metabolic Changes in Mice小麦粉摄入促进小鼠体重增加和代谢变化DOI: 10.1002/mnfr.70394 Acta Biochimica Polonica IF: 01.700Volume 72, Issue No.177Prevalence of vitamin D deficiency and related factors among adults in Tokat province, Türkiye: a community-based cross-sectional study土耳其托卡特省成人维生素D缺乏患病率及相关因素：一项基于社区的横断面研究DOI: 10.3389/abp.2025.15459 Health Psychol Behav Med IF: 02.200Volume 14, Issue 1No.178Developing a theory and evidence-based intervention for black African women using the COM-B model and behaviour change wheel: BALANCED programme运用COM-B模型与行为改变轮，为非裔黑人女性构建理论与循证干预：BALANCED项目DOI: 10.1080/21642850.2026.2616929 J Exp Orthop IF: 02.700Volume 13, Issue 1No.179Outcomes of total hip arthroplasty in obese patients with and without preoperative weight loss: A systematic review and meta-analysis肥胖患者全髋关节置换术结局：术前减重与未减重的系统评价与荟萃分析DOI: 10.1002/jeo2.70651 Frontiers in physiology IF: 03.400Volume 16, Issue No.180The role of impaired adipogenesis in insulin resistance among non-obese individuals脂肪生成障碍在非肥胖个体胰岛素抵抗中的作用DOI: 10.3389/fphys.2025.1739215 Journal of wrist surgery IF: 00.600Volume 15, Issue 1No.181Comparative Analysis of Comorbidities and Outcomes in Endoscopic versus Open Treatment of Carpal Tunnel Release in Patients with Rheumatoid Arthritis类风湿关节炎患者内镜与开放式腕管松解术比较分析DOI: 10.1055/s-0044-1791266 Front Clin Diabetes Healthc IF: 02.200Volume 6, Issue No.182Reduction of insulin resistance in 14-15-year-old students after the COVID-19 pandemic: a prospective study from Tsunan, JapanCOVID-19大流行后日本津南町14-15岁学生胰岛素抵抗的减少：一项前瞻性研究DOI: 10.3389/fcdhc.2025.1687294 Annals of neurosciences IF: 02.400Ahead of Print.No.183Association of Heart Rate Variability and NeuroCognitive Performance Among Metabolically Healthy Obese Adults: Cardio-psychological Based Approach心率变异性与神经认知功能的关联：针对代谢健康肥胖成年人的心脏心理学方法DOI: 10.1177/09727531251409528 J Educ Health Promot IF: 01.300Volume 14, Issue No.184Exploring the interplay between stress level, sleep quality, and body composition among university students: A cross-sectional study探究大学生压力水平、睡眠质量与身体成分之间的相互作用：一项横断面研究DOI: 10.4103/jehp.jehp_1947_24 J Educ Health Promot IF: 01.300Volume 14, Issue No.185Impact of sleep quality and physical activity on hypertension in adults: Findings from rural eastern India睡眠质量与体力活动对成人高血压的影响：来自印度东部农村地区的发现DOI: 10.4103/jehp.jehp_2133_24 bioRxivVolume 2026, Issue No.186Ovarian Hormones and Obesity Drive Th17-mediated Airway Inflammation through Estrogen Receptor Signaling卵巢激素与肥胖通过雌激素受体信号驱动Th17介导的气道炎症DOI: 10.64898/2025.12.02.691857 bioRxivVolume 2026, Issue No.187High-Fat Diet Induces Epigenetic and Metabolic Changes in Kisspeptin Neurons in Association with Obesity and Male Secondary Hypogonadism高脂饮食诱导Kisspeptin神经元的表观遗传和代谢改变，与肥胖及男性继发性性腺功能减退相关DOI: 10.64898/2025.11.30.691258 Sisli Etfal Hastan T?p Bul IF: 01.000Volume 59, Issue 3No.188Evaluation of Our Paediatric Patients Hospitalised with Covid-19 Diagnosis: Single Centre Experience我们因COVID-19诊断住院的儿科患者的评估：单中心经验DOI: 10.14744/SEMB.2025.73483 Curēus IF: 01.300Volume 17, Issue 12No.189Neurological Outcomes Following Surgical Resection of Intradural Extramedullary Spinal Tumors: A Retrospective Analysis Using the American Spinal Injury Association (ASIA) Impairment Scale使用美国脊髓损伤协会(ASIA)损伤量表评估硬膜内髓外脊髓肿瘤手术切除后的神经功能预后：一项回顾性分析DOI: 10.7759/cureus.99857 Curēus IF: 01.300Volume 17, Issue 12No.190Beyond Snoring: Unexpected Presentation of Obstructive Sleep Apnea不只是打鼾：阻塞性睡眠呼吸暂停的非典型表现DOI: 10.7759/cureus.99866 Curēus IF: 01.300Volume 17, Issue 12No.191Healthy Lifestyle Interventions for Non-communicable Disease Prevention in Saudi Arabia: A Scoping Review沙特阿拉伯非传染性疾病预防的生活方式干预：一项范围综述DOI: 10.7759/cureus.99800 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.192Effects of stress on bone health in children压力对儿童骨骼健康的影响DOI: 10.3389/fendo.2025.1715779 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.193Deciphering obesity: a conceptual overview and synthesis解码肥胖：概念性概览与综合DOI: 10.3389/fendo.2025.1738147 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.194Abdominal versus femoral subcutaneous fat gene expression in non-obese insulin resistant individuals非肥胖胰岛素抵抗个体腹部与大腿皮下脂肪基因表达对比DOI: 10.3389/fendo.2025.1684761 Obesity science & practice IF: 01.900Volume 12, Issue 1No.195Recent Insights Into Circulating Adipokines in Obesity: Systematic Review and Meta-Analysis肥胖中循环脂肪因子最新见解：系统综述与荟萃分析DOI: 10.1002/osp4.70113 Frontiers in nutrition IF: 05.100Volume 12, Issue No.196The excess body fat is a potential mediator between consumption of ultra-processed foods and cardiometabolic risk in normal-weight Brazilian children超重是超加工食品消费与巴西正常体重儿童心脏代谢风险之间潜在的中介因素DOI: 10.3389/fnut.2025.1726016 Public health nutrition IF: 03.000Ahead of Print.No.197Nutrition Inequities in the Deaf Community: A Call for Inclusive Public Health Action听障社区的营养不平等：呼吁包容性公共卫生行动DOI: 10.1017/S1368980026101864 Endocr Metab Immune Disord Drug Targets IF: 02.000Ahead of Print.No.198Effects of Swimming Exercise and L-Carnitine Administration on Insulin Resistance in Juvenile Obese Rats with Type 2 Diabetes游泳运动与L-肉碱干预对青少年肥胖2型糖尿病大鼠胰岛素抵抗的影响DOI: 10.2174/0118715303413143251031170236 J Dev Orig Health Dis IF: 01.500Volume 17, Issue No.199Mild fructose diet during periadolescent development increases emotionality, but not metabolic consequences of early life adversity in rats围青春期轻度果糖饮食增加大鼠的情绪性，但不加剧早期生活逆境的代谢后果DOI: 10.1017/S2040174425100433 Statistics in medicine IF: 01.800Volume 45, Issue 1-2No.200A Functional Approach to Testing Overall Effect of Interaction Between DNA Methylation and SNPs一种测试DNA甲基化与SNPs相互作用总体效应的功能方法DOI: 10.1002/sim.70364 Lupus IF: 01.900Ahead of Print.No.201Serum BAFF levels in pregnant patients with systemic lupus erythematosus系统性红斑狼疮孕妇患者的血清BAFF水平DOI: 10.1177/09612033261419984 Obesity reviews IF: 07.400Ahead of Print.No.202Effect of Citrus bergamia Supplementation on Body Composition in Humans: A Systematic Review and Meta-Analysis of Randomized Controlled Trials香柠檬补充剂对人体体成分影响的系统评价与荟萃分析：随机对照试验研究DOI: 10.1111/obr.70094 Childhood obesity IF: 01.400Ahead of Print.No.203Pragmatic Pilot Study of the Healthy Living Program: An Obesity Prevention and Treatment Program for Low-Income Hispanic Families Delivered Through Clinic-Community Partnership《健康生活计划》实用试点研究：一项通过诊所-社区合作为低收入西班牙裔家庭提供的肥胖预防与治疗计划DOI: 10.1177/21532176251410314 Asian J Endosc Surg IF: 00.900Volume 19, Issue 1No.204Short-Term Operative Outcomes of Loop Reconstruction for Duodenojejunal Bypass With Sleeve Gastrectomy: A Retrospective Study From a Single Japanese Academic Hospital十二指肠空肠旁路联合袖状胃切除术的环状重建的短期手术效果：一项来自日本单一学术医院的回顾性研究DOI: 10.1111/ases.70245 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.205Cardiometabolic implications of triglyceride-glucose index, remnant cholesterol, and vitamin D in normoglycemic Arab adolescents: a cross-sectional study甘油三酯-葡萄糖指数、残余胆固醇与维生素D对血糖正常阿拉伯青少年代谢心血管的意义：一项横断面研究DOI: 10.3389/fendo.2025.1674706 Curr Pharm Biotechnol IF: 02.600Ahead of Print.No.206Protective Role of Glibenclamide and Magnesium Sulfate in Fructoseinduced Type 2 Diabetes Mellitus格列本脲与硫酸镁在果糖诱导的2型糖尿病中的保护作用DOI: 10.2174/0113892010396082251107094426 Endocrinol Diabetes Metab IF: 02.600Volume 9, Issue 1No.207Association Between the Triglycerides-to-High-Density Lipoprotein-Cholesterol (TG/HDL-C) Ratio and Chronic Kidney Disease: A Systematic Review and Meta-Analysis of Observational Studies甘油三酯与高密度脂蛋白胆固醇比值（TG/HDL-C）与慢性肾脏病关联性的系统综述与荟萃分析DOI: 10.1002/edm2.70161 Curēus IF: 01.300Volume 17, Issue 12No.208Unanticipated Residual Gastric Contents in an Appropriately Fasted Pediatric Patient on Glucagon-Like Peptide-1 Receptor Agonist Therapy: A Case Report and Review of Perioperative ConsiderationsGLP-1受体激动剂治疗儿科患者中未预期的胃内容物残留：病例报告及围术期考量DOI: 10.7759/cureus.99731 Curēus IF: 01.300Volume 17, Issue 12No.209Safety and Synergy of Capmatinib Plus Stereotactic Radiotherapy in MET Exon 14-Mutated Non-Small Cell Lung Cancer: A Case Report卡马替尼联合立体定向放疗治疗MET外显子14突变非小细胞肺癌的安全性及协同作用：病例报告DOI: 10.7759/cureus.99838 Circulation IF: 38.600Ahead of Print.No.210Association of Statin Discontinuation in Pregnancy With Maternal Cardiovascular Health and Birth Outcomes: A Nationwide Cohort Study妊娠期停用他汀类药物与孕产妇心血管健康及出生结局的关联：一项全国队列研究DOI: 10.1161/CIRCULATIONAHA.125.078919 Frontiers in health services IF: 02.700Volume 5, Issue No.211Factors influencing cardiovascular disease screening uptake and implementation strategies to enhance cardiovascular disease screening uptake in Singapore adults: a multi-method study protocol影响新加坡成人心血管疾病筛查参与度的因素及提升筛查参与度的实施策略：一项多方法研究方案DOI: 10.3389/frhs.2025.1677666 Diabetes Technol Ther IF: 06.300Ahead of Print.No.212Association of Continuous Glucose Monitoring Metrics with Incident Diabetic Retinopathy: A Real-World Long-Term Study连续葡萄糖监测指标与新发糖尿病视网膜病变的关联：一项长期真实世界研究DOI: 10.1177/15209156261416922 Diabetes Technol Ther IF: 06.300Ahead of Print.No.213Diagnostic Accuracy of Artificial Intelligence-Enabled Retinal Biomarkers for Detecting Type 2 Diabetes and Prediabetes Among Asian Indians [DART Study]人工智能视网膜生物标志物检测亚洲印度人2型糖尿病与前驱糖尿病的诊断准确性[DART研究]DOI: 10.1177/15209156261417296 Diabetes Technol Ther IF: 06.300Ahead of Print.No.214Accuracy of Dexcom One+ in Patients with Diabetes or Stress Hyperglycemia Hospitalized in Cardiac Intensive Care UnitDexcom One+在心脏重症监护室糖尿病或应激性高血糖患者中的准确性DOI: 10.1177/15209156251407717 Diabetes Technol Ther IF: 06.300Ahead of Print.No.215Automated Insulin Delivery Associated with Superior Glycemic Outcomes in Type 1 Diabetes: A Swedish National Registry Analysis自动化胰岛素输注与1型糖尿病更优血糖结局相关：一项瑞典国家注册研究分析DOI: 10.1177/15209156251414976 Diabetes Technol Ther IF: 06.300Ahead of Print.No.216Consistent Benefit of Control-IQ+ Automated Insulin Delivery Across a Range of Characteristics of Adults with Type 2 DiabetesControl-IQ+自动化胰岛素输注对2型糖尿病成人患者不同特征的一致益处DOI: 10.1177/15209156261416920 Diabetes Technol Ther IF: 06.300Ahead of Print.No.217The Effect of Automated Insulin Delivery Systems on Sleep Quality and Quantity in Type 1 Diabetes: A Systematic Review and Meta-Analysis自动化胰岛素输送系统对1型糖尿病患者睡眠质量与时间的影响：一项系统综述与荟萃分析DOI: 10.1177/15209156251411925 Diabetes Technol Ther IF: 06.300Ahead of Print.No.218Overcoming Closed-Loop System Limits: Diluted Insulin Improves Glycemic Control and Reduces Nighttime Hypoglycemia in Toddlers with Low Insulin Requirements克服闭环系统局限：稀释胰岛素改善低胰岛素需求幼儿的血糖控制并减少夜间低血糖DOI: 10.1177/15209156251414981 Diabetes Technol Ther IF: 06.300Ahead of Print.No.219Outcomes in United States Veterans on Insulin Pumps Following Rapid Deployment of Telehealth Care快速部署远程医疗护理后美国退伍军人胰岛素泵使用者的结局DOI: 10.1177/15209156251403561 Diabetes Technol Ther IF: 06.300Ahead of Print.No.220Clinical Impact of Continuous Glucose Monitoring in Noninsulin Treated Type 2 Diabetes: A Review连续葡萄糖监测在非胰岛素治疗2型糖尿病中的临床影响：一篇综述DOI: 10.1177/15209156251414980 Health education & behavior IF: 02.100Ahead of Print.No.221Eating Behavior Traits and Success in Dietary Changes in Men with Prediabetes - the T2D-GENE Intervention饮食行为特征与糖尿病前期男性饮食改变成功的关系——T2D-GENE干预研究DOI: 10.1177/10901981251411226 Wound repair and regeneration IF: 03.400Volume 34, Issue 1No.222Plain Radiography for Diagnosing and Monitoring Foot Osteomyelitis in Persons With Diabetes: Accuracy, Limitations and Clinical Utility平片放射学在诊断和监测糖尿病患者足部骨髓炎中的应用：准确性、局限性与临床效用DOI: 10.1111/wrr.70128 J Comp Eff Res IF: 02.500Ahead of Print.No.223Reshaping the cardiovascular continuum in the management of arterial and venous cardiovascular disease: a narrative review重塑心血管连续谱：动脉与静脉心血管疾病管理的叙事性综述DOI: 10.57264/cer-2025-0162 BMJ medicine IF: 10.000Volume 5, Issue 1No.224Physical activity types, variety, and mortality: results from two prospective cohort studies体力活动类型、多样性与死亡率：两项前瞻性队列研究结果DOI: 10.1136/bmjmed-2025-001513 Transgender health IF: 01.800Volume 10, Issue 6No.225The Role of Body Composition Assessment in Tailoring Gender-Affirming Treatment for Transgender/Gender Diverse Youth身体成分评估在定制跨性别/性别多元化青少年性别肯定治疗中的作用DOI: 10.1089/trgh.2022.0218 North Clin Istanb IF: 00.900Volume 12, Issue 6No.226Evaluation of sociodemographic and clinical characteristics of dermatochalasis patients: A retrospective epidemiologic study in a tertiary care eye clinic皮肤病患者的流行病学研究：一项三级眼科诊所的回顾性研究DOI: 10.14744/nci.2025.25936 Front Clin Diabetes Healthc IF: 02.200Volume 6, Issue No.227Improving self-care, HbA1c control, and quality of life in type 2 diabetes: a self-regulation intervention based on the individual and family self-management theory改善2型糖尿病自我护理、HbA1c控制及生活质量：一项基于个体和家庭自我管理理论的自律干预DOI: 10.3389/fcdhc.2025.1712334 MedComm IF: 10.700Volume 7, Issue 2No.228The Gut Microbiota as a Mediator in the Relationship Between Dietary Patterns and Depression肠道菌群作为膳食模式与抑郁症关系的中介DOI: 10.1002/mco2.70562 bioRxivVolume 2026, Issue No.229Harmine Selectively Drives Human Beta Cell Differentiation and Function Via Protein Kinase A PathwaysHarmine通过蛋白激酶A通路选择性驱动人类β细胞分化与功能DOI: 10.64898/2025.12.07.692818 Jornal Vascular Brasileiro IF: 01.000Volume 24, Issue No.230Incidence and risk factors for contrast-induced nephropathy after angioplasty: an observational retrospective study血管成形术后造影剂肾病的发生率与危险因素：一项回顾性观察研究DOI: 10.1590/1677-5449.202500282 Frontiers in oncology IF: 03.300Volume 15, Issue No.231KEAP1 mutations activate the NRF2 pathway to drive cell growth and migration, and attenuate drug response in thyroid cancerKEAP1突变激活NRF2通路驱动甲状腺癌细胞生长与迁移并减弱药物反应DOI: 10.3389/fonc.2025.1685379 Case Reports in Dentistry IF: 00.900Volume 2026, Issue No.232Refractory Gingival Enlargement: A Critical Oral Clue to Early-Stage Granulomatosis With Polyangiitis-A Case Report and Literature Review难治性牙龈肥大：早期肉芽肿性多血管炎的一个关键口腔线索——病例报告与文献回顾DOI: 10.1155/crid/8443058 FCVM IF: 02.900Volume 12, Issue No.233Clinical outcomes of aortic stenosis patients undergoing Impella-supported high-risk percutaneous coronary intervention主动脉瓣狭窄患者接受Impella支持的高风险经皮冠状动脉介入治疗的临床结果DOI: 10.3389/fcvm.2025.1638259 Curēus IF: 01.300Volume 17, Issue 12No.234A Literature Review of the Renal Manifestations in Pediatric Celiac Disease and Its Associated Clinical Implications儿童乳糜泻肾损伤表现及其临床意义的文献综述DOI: 10.7759/cureus.99773 Curēus IF: 01.300Volume 17, Issue 12No.235Hypertension and Risk of Stroke: A Systematic Review and Meta-Analysis高血压与卒中风险：一项系统性回顾与荟萃分析DOI: 10.7759/cureus.99863 Curēus IF: 01.300Volume 17, Issue 12No.236Exploring the Potential Observations Between Geomagnetic Activity and Cardiovascular Events: A Scoping Review探索地磁活动与心血管事件间的潜在关联：一项范围综述DOI: 10.7759/cureus.99851 Ther Adv Ophthalmol IF: 02.300Volume 18, Issue No.237Exploring hyperbaric oxygen therapy for central retinal artery occlusion beyond 24 h: case report探索高压氧疗法治疗超过24小时的中心视网膜动脉阻塞：病例报告DOI: 10.1177/25158414251405382 JIMD reports IF: 01.800Volume 67, Issue 1No.238Identification of Additional Cases of Severe Neonatal GABA-Transaminase Deficiency严重新生儿期GABA转氨酶缺乏症额外病例的识别DOI: 10.1002/jmd2.70069 Bioeng Transl Med IF: 05.700Volume 11, Issue 1No.239Vitrification and rapid rewarming of precision-cut liver slices for pharmacological and biomedical research用于药理学和生物医学研究的精密肝切片的玻璃化冷冻与快速复温DOI: 10.1002/btm2.70045 J Diabetes Metab Disord IF: 01.600Volume 25, Issue 1No.240AMPK as a central regulator of metabolic memory: mechanisms and therapeutic opportunitiesAMPK：代谢记忆的核心调节器——作用机制与治疗前景DOI: 10.1007/s40200-026-01859-x Curēus IF: 01.300Volume 17, Issue 12No.241Spectrum of Cardiac Complications in Diabetic Patients in Rural Uttar Pradesh, India: A Hospital-Based Study印度北方邦农村糖尿病患者心脏并发症谱系：一项医院为基础的研究DOI: 10.7759/cureus.99734 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.242Case report: Takotsubo cardiomyopathy and cardiac arrest in a 9-year-old girl with new-onset diabetes presenting with diabetic ketoacidosis: the chicken or the egg?病例报告：新发糖尿病伴酮症酸中毒的9岁女孩发生Takotsubo心肌病与心脏骤停：孰因孰果？DOI: 10.3389/fendo.2025.1723428 Curēus IF: 01.300Volume 17, Issue 12No.243Ectopic Acromegaly Caused by Peripheral Ectopic Growth Hormone Hypersecretion: A Case Report and Literature Review异位肢端肥大症：一例外周异位生长激素过度分泌病例报告与文献回顾DOI: 10.7759/cureus.99840 Frontiers in endocrinology IF: 04.600Volume 16, Issue No.244Prolonged alpha-blockade and doxazosin are associated with hypertensive crisis in pheochromocytoma surgery嗜铬细胞瘤手术中，延长α受体阻滞及使用多沙唑嗪与高血压危象相关DOI: 10.3389/fendo.2025.1682912 J Educ Health Promot IF: 01.300Volume 14, Issue No.245Maternal-physiological parameters and prenatal mindfulness interventions - A scoping review母体生理参数与产前正念干预——范围综述DOI: 10.4103/jehp.jehp_2061_24 217 Diabetes Mellitus(DM) 糖尿病 95 Obesity 肥胖症 87 Insulin 胰岛素 23 Type 2 diabetes mellitus(T2DM) 2型糖尿病 12 Metformin 二甲双胍 12 Metabolic Syndrome 代谢综合征 7 Semaglutide 司美格鲁肽 7 Diabetic Retinopathy 糖尿病视网膜病 6 Glucagon-Like Peptide-1 Receptor Agonists(GLP-1RA) 胰高血糖素样肽-1受体激动剂 6 Gestational Diabetes Mellitus(GDM) 妊娠糖尿病 5 Hypoglycemic Agents 降糖药 5 Diabetic Foot 糖尿病足 4 Liraglutide 利拉鲁肽 4 Type 1 diabetes mellitus(T1DM) 1型糖尿病 4 Tirzepatide 替尔泊肽 3 Diabetic Cardiomyopathies 糖尿病心肌病 3 Gabapentin 加巴喷丁 3 Pregabalin 普瑞巴林 3 Diabetic Peripheral Neuropathy(PDN) 糖尿病周围神经病变 2 Diabetic Neuropathies 糖尿病性神经病变 2 Diabetic Kidney Disease(DKD) 糖尿病肾脏病 2 Dipeptidyl-Peptidase IV Inhibitors(DPP-4i) 二肽基肽酶-4抑制剂 1 Vildagliptin 维格列汀 1 Dulaglutide 度拉糖肽 1 Sodium-Glucose Transporter 2 Inhibitors(SGLT-2i) 钠-葡萄糖协同转运蛋白2抑制剂 1 Empagliflozin 恩格列净 1 Ertugliflozin 艾托格列净 1 Ipragliflozin 依格列净 1 Diabetes Complications 糖尿病并发症 1 Diabetic acidosis 糖尿病性酸中毒编辑：牛祥审校：牛祥

临床结果临床研究

2026-01-13

·CVDAILY

全球糖尿病速递（第013期）｜糖尿病门诊电子病历、糖皮质激素的血糖效应、运动依从性干预措施

*本资料仅供医疗卫生专业人士参考，请勿向非医疗卫生专业人士发放截至01月13日15点59分，近期共有 433 本期刊发布了 850 篇文章，其中糖尿病相关的文章共 318 篇，覆盖 37 个领域的内容。中国专家参与发表的文章有 55 篇。今日，影响因子最高的文章刊登在 Signal transduction and targeted therapy (IF: 52.700) 期刊上。今日头条 Headlines 01 Int J Med Inform IF: 04.100 临床医生对电子病历在糖尿病门诊护理中应用的视角：一项定性研究 Wang, Wenyong, Samadbeik, Mahnaz, Puri, Gaurav, McLeod, Donald S A, Lobo, Elton, Duong, Tuan, etc. 近日，一项定性研究深入探讨了临床医生在糖尿病门诊护理中使用电子病历（EMR）的真实体验与看法。该研究由Wenyong Wang等共同完成，旨在填补EMR在特定门诊场景下影响证据的空白。研究在澳大利亚昆士兰州一家大都市糖尿病服务中心开展，采用了焦点小组的形式，共有22名来自不同岗位的临床医生参与，包括医生、护士和专职医疗人员。数据分析结合了“Quintuple Aim”（五重目标）框架和“技术接受模型”，以期全面评估EMR对医疗质量、效率及医护人员体验的多维度影响。研究发现，临床医生对EMR的感受呈现显著的“双面性”。积极的一面是，医生们普遍认为，EMR提高了工作效率，使得获取患者历史信息、检验结果和既往处方变得前所未有的便捷。在安全性方面，系统内置的处方审核与警示功能，被认为有效降低了用药错误的风险。然而，临床医生也提及系统存在导航复杂、界面不够直观、偶发技术故障等问题，影响了使用的流畅度。更为突出的是“警报疲劳”，即系统过多的弹窗和提醒，可能导致重要信息被忽略，反而增加了认知负荷。此外，如何在系统中进行恰当、高效的文档记录，以及如何应对患者因知晓EMR存在而产生的不同期望，都让临床人员感到压力。研究还指出，初期庞杂而缺乏针对性的培训，也加重了医护人员的适应负担。综合这些正反两方面的体验，研究得出结论：在当前糖尿病门诊场景下，EMR确实在提升信息可及性、工作流程效率和医疗安全方面发挥了关键作用。但同时，其现有的设计逻辑和部署方式，也给临床医生的工作体验和幸福感带来了不容忽视的负面影响。研究人员特别指出，像糖尿病这类需要长期、综合数据管理的慢性病，其复杂的护理需求（例如血糖趋势的整合分析）可能尚未被通用型EMR系统完美支持。基于这些发现，研究团队强调，EMR的部署与优化应被视为一项持续的质量改进工程，而非一次性技术安装。他们呼吁，未来的努力方向应包括大力改善系统可用性、提供分角色、场景化的精准培训、确保技术基础设施的稳定可靠，并且必须让一线临床医生深度参与到系统的优化设计中。未来的研究应解决可用性挑战，增强整合，并确保临床医生和患者的观点共同引领数字健康转型。本文由韩玉莲编辑扫描二维码查看源文 Int J Med Inform | Ahead of Print. 10.1016/j.ijmedinf.2026.106275 02 Diabetes, obesity & metabolism IF: 05.700 糖皮质激素在1型糖尿病中应用的系统综述：血糖效应与临床管理策略 Katz, Alexandra, Shulkin, Aidan, Housni, Asmaa, Roy-Fleming, Amélie, Rabasa-Lhoret, Rémi, Yale, Jean-Francois, etc. 近日，一项Alexandra Katz等学者发表的系统综述，深入探讨了糖皮质激素（GCs）在1型糖尿病患者中的应用及其对血糖管理带来的挑战。糖皮质激素是治疗炎症和自身免疫性疾病的常用药物，但其一个众所周知的副作用是诱发高血糖。对于依赖胰岛素治疗的1型糖尿病患者而言，如何在GCs治疗期间调整胰岛素剂量以维持血糖稳定，是一个复杂的临床难题，且目前缺乏清晰的管理建议。这项系统性研究检索了截至2025年8月的多个医学数据库，共纳入了22项相关研究，涉及总计368名成年1型糖尿病患者。分析结果表明，无论采用何种剂型、剂量或给药途径，GCs治疗均与明显的血糖波动和胰岛素需求量上升密切相关。无论是GCs口服或静脉给药，胰岛素需求都需要在基线水平上大幅增加，部分研究中增幅高达70%。研究进一步揭示了不同临床情境下的差异。在妊娠期使用产前糖皮质激素时，通过结构化的皮下或静脉胰岛素输注方案进行管理，效果较为理想。而对于关节内注射等局部给药的GCs，其引起的血糖升高可能延迟出现，但持续时间较长，需要更长时间的严密血糖监测。随着糖尿病管理技术的进步，自动胰岛素输注系统（AID）在此场景下的作用也受到了关注。现有证据提示，AID系统可能有助于减轻GCs引发的血糖升高幅度，但系统仍然需要使用者根据情况进行主动干预和调整。基于现有证据，综述指出，GCs治疗确实会显著扰乱1型糖尿病患者的血糖稳定性。其影响程度和模式取决于药物本身特性、给药方式以及患者个体因素和具体的临床背景。目前，最为切实可行的管理策略是采取主动、个体化的方法，即根据所用GCs的药代动力学特点，预先规划和调整胰岛素剂量，并辅以频繁的血糖监测或连续血糖监测技术的使用。研究者最后强调，为了优化1型糖尿病患者的合并用药管理，未来仍需开展更多研究，以建立基于高质量证据的临床指南，并进一步阐明像AID这样的先进技术在应对GCs相关高血糖中的确切角色和最佳使用方案。本文由韩玉莲编辑扫描二维码查看源文 Diabetes, obesity & metabolism | Ahead of Print. 10.1111/dom.70465 03 Journal of obesity IF: 03.900 促进超重或肥胖人群运动依从性的干预措施有效性：一项系统综述 Rodrigues, Matheus de Sena Anchieta, Atanasio, Lívia de Melo, Dos Santos, Isis Kelly, da Silva, José Carlos Gomes, Cabral, Breno Guilherme de Araujo Tinoco, Dantas, Paulo Moreira Silva, etc. 近日，一项发表在Journal of Obesity上的系统综述研究，为我们理解如何帮助超重或肥胖人群坚持运动提供了新的证据。该研究系统评估了旨在提升该人群运动依从性的各种干预措施，揭示了可能有效的策略，同时也指出了当前研究领域的局限。这项研究由Rodrigues等人完成，他们检索了包括MEDLINE、Embase在内的五大数据库，最终纳入了17项符合标准的随机对照试验。这些研究覆盖了美国、加拿大、澳大利亚、欧洲等多个地区，干预时长从12周到2年不等，旨在探索不同方法对运动坚持情况的影响。分析结果显示，在多种干预形式中，**以小组形式开展的运动项目**以及**由受过培训的专业人员直接监督的干预**，显示出与更高运动依从性相关的积极趋势。这意味着，在集体环境中锻炼或获得专业的现场指导，可能更有利于超重或肥胖个体克服障碍，将运动计划坚持下去。而干预措施是否结合了饮食指导或心理行为策略、运动的频率、每次的时长和强度如何，以及参与者的体重，在这些研究中都未发现它们与运动依从性水平存在稳定的关联。大多数研究存在中度至高度的偏倚风险，这意味着其结果可能受到各种混杂因素或设计缺陷的影响，从而限制了当前证据的可靠性。因此，尽管本综述指出了集体与有监督的干预措施可有效提高超重或肥胖成年人的锻炼依从性，但研究者强调乐未来在该领域进行更严谨、设计更精良的随机对照试验的必要性。未来的研究需要更清晰地描述干预细节，采用更客观、一致的依从性测量方法，并关注如何维持长期的运动参与，尤其是在干预数月之后依从性可能下降的关键时期。本文由韩玉莲编辑扫描二维码查看源文 Journal of obesity | Volume 2025, Issue 10.1155/jobe/4164477 中国发表（55） China J Health Popul Nutr IF: 02.800Ahead of Print.No.01Time-restricted eating in overweight and obese adults: an evidence summary and clinical recommendations限时进食在超重和肥胖成人中的应用：一项证据总结与临床建议DOI: 10.1186/s41043-025-01221-6 BMC musculoskeletal disorders IF: 02.400Ahead of Print.No.02Does metabolically healthy obesity increase the risk of knee and hand osteoarthritis? A population-based cohort study代谢健康型肥胖是否会增加膝与手骨关节炎风险？一项基于人群的队列研究DOI: 10.1186/s12891-026-09495-5 BMC pediatrics IF: 02.000Ahead of Print.No.03Association between dietary folate intake and obesity in children and adolescents: a cross-sectional NHANES study饮食中叶酸摄入量与儿童青少年肥胖的关联：一项横断面NHANES研究DOI: 10.1186/s12887-025-06490-y Appl Microbiol Biotechnol IF: 04.300Ahead of Print.No.04Distinct oral and fecal microbiota composition in preschool children with overweight/obesity: a cross-sectional study学龄前超重/肥胖儿童存在独特的口腔和粪便微生物群组成：一项横断面研究DOI: 10.1007/s00253-025-13685-x International journal of obesity IF: 03.800Ahead of Print.No.05Multidimensional risk impact of obesity on breast cancer incidence, treatment, and prognosis肥胖对乳腺癌发病率、治疗和预后的多维风险影响DOI: 10.1038/s41366-025-02008-9 Cellular signalling IF: 03.700Ahead of Print.No.06Role of CTRP9 in obesity-associated microglial dysregulation: Promoting lipophagy via the PI3K/AKT/FOXO1 signaling pathwayCTRP9在肥胖相关小胶质细胞失调中的作用：通过PI3K/AKT/FOXO1信号通路促进脂自噬DOI: 10.1016/j.cellsig.2026.112358 Acta clinica belgica : IF: 01.100Ahead of Print.No.07A comprehensive review and meta-analysis of relationship between age of onset or duration of type 2 diabetes and mortality involving more than 2.85 million patients涵盖超285万患者的大型综述与荟萃分析：全面评估2型糖尿病发病年龄或病程与死亡率的关系DOI: 10.1080/17843286.2026.2615091 Environmental research IF: 07.700Volume 291, Issue No.08Associations of concomitant exposure to outdoor light at night, air pollution, and greenness with metabolic syndrome: A cohort study in China夜间户外光、空气污染与绿地暴露与代谢综合征的关联性研究：一项中国队列研究DOI: 10.1016/j.envres.2025.123590 Biogerontology IF: 04.100Volume 27, Issue 1No.09FOXO: a key target in regulating aging and age-related diseasesFOXO：调控衰老与年龄相关疾病的关键靶点DOI: 10.1007/s10522-025-10380-2 European journal of pharmacology IF: 04.700Ahead of Print.No.10SIRT1-mediated YAP deacetylation suppresses myocardial hypertrophy in diabetic cardiomyopathySIRT1介导的YAP去乙酰化抑制糖尿病心肌病中的心肌肥大DOI: 10.1016/j.ejphar.2026.178538 BMC Cardiovascular Disorders IF: 02.300Ahead of Print.No.11Association of triglyceride-glucose index with all-cause mortality in critically ill non-diabetic ischemic stroke: a retrospective cohort study based on the MIMIC-IV database甘油三酯-葡萄糖指数与危重非糖尿病缺血性卒中患者全因死亡率的关联：一项基于MIMIC-IV数据库的回顾性队列研究DOI: 10.1186/s12872-025-05458-1 BMC infectious diseases IF: 03.000Ahead of Print.No.12Correlation analysis between the prevalence of hyperuricemia and the triglyceride-glucose index in adult patients with brucellosis成人布鲁氏菌病患者高尿酸血症患病率与甘油三酯-葡萄糖指数的相关性分析DOI: 10.1186/s12879-026-12532-2 Eur J Med Res IF: 03.400Ahead of Print.No.13Modified cardiometabolic index outperforms conventional indices in discriminating relative muscle loss: a cross-sectional analysis of NHANES 2011-2018改良心脏代谢指数在鉴别相对肌肉减少方面优于传统指数：一项基于NHANES 2011-2018的横断面分析DOI: 10.1186/s40001-026-03879-y Community dental health IF: 01.000Ahead of Print.No.14Effect of type 1 diabetes on oral lichen planus mediated by IL-101型糖尿病通过IL-10介导对口腔扁平苔藓的影响DOI: 10.1177/0265539X261416458 Yingyong shengtai xuebaoVolume 37, Issue 1No.15[Effects of γ-aminobutyric acid and chlorinated hemin composite coating on seed germination and seedling growth of Psathyrostachys juncea under drought and salt stresses]γ-氨基丁酸与氯化血红素复合包衣对新麦草种子萌发及幼苗生长在干旱与盐胁迫下的影响DOI: 10.13287/j.1001-9332.202601.011 NeuroImage IF: 04.500Volume 325, Issue No.16Aberrant thalamic GABA-network coupling as a neural signature of insomnia severity in major depressive disorder丘脑GABA-网络耦合异常作为重度抑郁症失眠严重程度的神经特征DOI: 10.1016/j.neuroimage.2025.121639 Current eye research IF: 02.000Ahead of Print.No.17Association Between Pancreatic β-Cell Function and Quantitative OCT Angiography Metrics in Patients with Type 2 Diabetes Without Clinical Diabetic Retinopathy2型糖尿病无临床视网膜病变患者胰腺β细胞功能与定量OCTA指标之间的关联DOI: 10.1080/02713683.2026.2612760 Cell & bioscience IF: 06.200Ahead of Print.No.18Combination of GLP-1 receptor agonist and Akkermansia muciniphila Akk11 reduces adiposity and ameliorates MASLD in T2D miceGLP-1受体激动剂与嗜黏蛋白阿克曼氏菌Akk11联用减轻2型糖尿病小鼠肥胖并改善MASLDDOI: 10.1186/s13578-025-01525-4 Food & function IF: 05.400Volume 17, Issue 1No.19Pro-inflammatory and pro-oxidant diets and CKD risk across cardiovascular-kidney-metabolic syndrome stages: a multi-omics mediation analysis促炎与促氧化饮食在心血管-肾脏-代谢综合征各阶段与慢性肾病风险：一项多组学中介分析DOI: 10.1039/d5fo03952e Food & function IF: 05.400Volume 17, Issue 1No.20Bifidobacterium animalis subsp. lactis Bbm-19 ameliorates insomnia by remodeling the gut microbiota and restoring γ-aminobutyric acid and serotonin signaling动物双歧杆菌乳亚种Bbm-19通过重塑肠道菌群及恢复γ-氨基丁酸与血清素信号改善失眠DOI: 10.1039/d5fo04374c Circulation IF: 38.600Volume 153, Issue 2No.21Letter by Zhao Regarding Article, "Oral Semaglutide and Cardiovascular Outcomes in People With Type 2 Diabetes, According to SGLT2i Use: Prespecified Analyses of the SOUL Randomized Trial"Zhao的来函：关于文章“口服司美格鲁肽与2型糖尿病患者心血管结局：基于SGLT2i使用的SOUL随机试验预设分析”DOI: 10.1161/CIRCULATIONAHA.125.076451 J Asian Nat Prod Res IF: 01.300Ahead of Print.No.22Research on the effects and mechanisms of the Yiqi Huoxue Recipe in improving renal injury in diabetic nephropathy through the HIF-1 pathway基于HIF-1通路探讨益气活血方改善糖尿病肾病肾损伤的作用及机制研究DOI: 10.1080/10286020.2025.2602695 The FASEB journal : IF: 04.200Volume 40, Issue 2No.23C-X-C Motif Chemokine Ligand 3 as a Potential Biomarker for Diagnosis and Prognosis of Diabetic Kidney DiseaseC-X-C基序趋化因子配体3作为糖尿病肾脏病诊断和预后的潜在生物标志物DOI: 10.1096/fj.202502236R GeroScience IF: 05.400Ahead of Print.No.24Life-course body shape trajectories and cerebral oxygen metabolism in community-dwelling older adults社区老年人生命周期体型轨迹与脑氧代谢DOI: 10.1007/s11357-025-02082-x Clin Transl Oncol IF: 02.500Ahead of Print.No.25Single-cell and spatial transcriptomics reveal mTOR-driven cellular fate of spindle cells and immune evasion in classic Kaposi's sarcoma单细胞与空间转录组学揭示经典型卡波西肉瘤中mTOR驱动的纺锤体细胞命运与免疫逃逸DOI: 10.1007/s12094-025-04063-0 Apoptosis IF: 08.100Volume 31, Issue 1No.26Propofol attenuates angiogenesis by activating endoplasmic reticulum stress to suppress TFAP2C-driven VEGFA transcription丙泊酚通过激活内质网应激抑制TFAP2C驱动的VEGFA转录来减弱血管生成DOI: 10.1007/s10495-025-02214-w Cardiovascular Drugs and Therapy IF: 03.100Ahead of Print.No.27Empagliflozin Supplementation in Cardioplegic Solution Improves Donor Heart Preservation by Maintaining Mitochondrial Homeostasis在心脏停搏液中补充恩格列净通过维持线粒体稳态改善供体心脏保存DOI: 10.1007/s10557-026-07834-1 Archives of osteoporosis IF: 02.800Volume 21, Issue 1No.28The contested association between MASLD and osteoporosis: a narrative review of heterogeneous evidence and modifying factorsMASLD与骨质疏松的关联备受争议：一项关于异质性证据与修饰因子的叙述性综述DOI: 10.1007/s11657-025-01639-9 Advanced materials IF: 26.800Ahead of Print.No.29An AI-embedded, Wearable Dual Closed-Loop Insulin Delivery System for Precision Diabetes Management一种用于精准糖尿病管理的AI嵌入式可穿戴双闭环胰岛素输送系统DOI: 10.1002/adma.202514945 Advanced science IF: 14.100Ahead of Print.No.30HMGB2-RAD21 Axis Promotes Fibro/Adipogenic Progenitor Proliferation and Regulates Fat InfiltrationHMGB2-RAD21轴通过促进纤维/脂肪组细胞增殖调控脂肪浸润DOI: 10.1002/advs.202514363 World J Exp MedVolume 15, Issue 3No.31Systematic review and risk factor analysis of post-vitrectomy silicone oil migration to the central nervous system玻璃体切除术后硅油向中枢神经系统迁移的系统性综述和危险因素分析DOI: 10.5493/wjem.v15.i3.106429 Food Science and Biotechnology IF: 03.100Volume 35, Issue 1No.32Synergistic modulation of metabolic disorders by konjac glucomannan and Polygonatum cyrtonema Hua polysaccharides: integrated insights from in vitro digestion, gut microbiota, and hepatic metabolomics魔芋葡甘聚糖与黄精多糖协同调控代谢紊乱：来自体外消化、肠道菌群和肝脏代谢组学的综合见解DOI: 10.1007/s10068-025-02015-6 Food Science and Biotechnology IF: 03.100Volume 35, Issue 1No.33Active ingredients, nutrition values and health-promoting effects of aboveground parts of rhubarb: a review大黄地上部分的活性成分、营养价值与健康促进功效综述DOI: 10.1007/s10068-025-01919-7 Food science & nutrition IF: 03.800Volume 14, Issue 1No.34Nobiletin Ameliorates Skeletal Muscle Performance in D-Galactose-Induced Aging Mice by Boosting Aerobic Metabolism川陈皮素通过促进有氧代谢改善D-半乳糖诱导衰老小鼠的骨骼肌性能DOI: 10.1002/fsn3.71416 Clinical case reports IF: 00.600Volume 14, Issue 1No.35Central Diabetes Insipidus in Suprasellar Germ Cell Tumor Paradoxically Presenting With Oliguria鞍上生殖细胞瘤所致中枢性尿崩症矛盾性表现为少尿DOI: 10.1002/ccr3.71832 Quant Imaging Med Surg IF: 02.300Volume 16, Issue 1No.36A novel computed tomography-based algorithm for the quantitative identification of lumbar spine-localized trabecular bone loss in patients with type 2 diabetes mellitus基于新型计算机断层扫描算法定量识别2型糖尿病患者腰椎局部骨小梁骨丢失DOI: 10.21037/qims-2025-1312 Journal of clinical nursing IF: 03.500Ahead of Print.No.37Comment on 'Dyadic Patterns of Patient and Caregiver Engagement in Type 2 Diabetes Mellitus Care': Innovative Directions Beyond Static Profiles评《Dyadic Patterns of Patient and Caregiver Engagement in Type 2 Diabetes Mellitus Care》：超越静态特征的创新方向DOI: 10.1111/jocn.70208 Analytical methods IF: 02.600Ahead of Print.No.38A highly sensitive LC-MS/MS method for quantification of AB-38b in rat plasma, liver and kidney tissues: application to a pharmacokinetic study用于定量大鼠血浆、肝及肾组织中AB-38b的高灵敏度LC-MS/MS方法：在药代动力学研究中的应用DOI: 10.1039/d5ay01136a World J Exp MedVolume 15, Issue 3No.39PI3K/AKT/GSK3β regulatory axis in bone mesenchymal stem cells initiates diabetic myocardial infarction via miR-142-3p骨髓间充质干细胞通过miR-142-3p调控的PI3K/AKT/GSK3β通路影响糖尿病心肌梗死DOI: 10.5493/wjem.v15.i3.103948 Digital health IF: 03.300Volume 12, Issue No.40Development of an explainable machine learning model for predicting poststroke anxiety: A multicenter study using Shapley Additive Explanations and nomogram visualization基于SHAP和列线图可视化的可解释机器学习模型预测卒中后焦虑：一项多中心研究DOI: 10.1177/20552076251412575 Int J Ophthalmol IF: 01.800Volume 19, Issue 1No.41Contiguous orbital inflammation from paranasal sinus abnormalities in etiology of thyroid-associated ophthalmopathy鼻旁窦异常引起的毗邻性眼眶炎症在甲状腺相关眼病病因学中的作用DOI: 10.18240/ijo.2026.01.13 Chin J Cancer Res IF: 06.300Volume 37, Issue 6No.42Leukemia epidemiology in China: Burden, trends, and determinants in the 21st century中国白血病流行病学：21世纪的疾病负担、趋势与决定因素DOI: 10.21147/j.issn.1000-9604.2025.06.03 J Diabetes Metab Disord IF: 01.600Volume 25, Issue 1No.43Body mass index mediates the association between serum fibroblast growth factor-19 and diabetes体重指数介导血清成纤维细胞生长因子-19与糖尿病之间的关联DOI: 10.1007/s40200-025-01850-y Annals of medicine IF: 04.300Volume 58, Issue 1No.44Letter to the Editor regarding: 'Global epidemiology of diabetes and prediabetes in lean or non-obese patients with NAFLD: a systematic review and meta-analysis'关于瘦型或非肥胖NAFLD患者中糖尿病与前驱糖尿病全球流行病学特征的系统综述和荟萃分析DOI: 10.1080/07853890.2026.2614829 Artif Cells Nanomed Biotechnol IF: 04.500Volume 54, Issue 1No.45Detection of pathogenic novel intronic splicing variants in the KIDINS220 gene causes motor developmental delay在KIDINS220基因中检测到致病性的新型内含子剪接变异导致运动发育迟缓DOI: 10.1080/21691401.2026.2612914 The FASEB journal : IF: 04.200Volume 40, Issue 2No.46Gpx4 Deletion-Mediated Macrophage Ferroptosis Alleviates Obesity-Associated Insulin Resistance巨噬细胞Gpx4缺失介导的铁死亡缓解肥胖相关的胰岛素抵抗DOI: 10.1096/fj.202503596R Int J Ophthalmol IF: 01.800Volume 19, Issue 1No.47Ranibizumab on optic disc perfusion in central retinal vein occlusion雷珠单抗对视网膜中央静脉阻塞患者视盘血流灌注的影响DOI: 10.18240/ijo.2026.01.10 Food science & nutrition IF: 03.800Volume 14, Issue 1No.48Astragalus membranaceus-Salvia miltiorrhiza Decoction Ameliorates Metabolic Syndrome and Gut Microbiota Dysbiosis Induced by High-Fat Diet: A Comparative Study黄芪-丹参煎剂改善高脂饮食诱导的代谢综合征与肠道菌群失调：一项比较研究DOI: 10.1002/fsn3.71436 RC IF: 01.300Volume 26, Issue 12No.49The Relationship Between the C-reactive Protein-Triglyceride Glucose Index and the Risk of Coronary Heart Disease Alongside the Severity of Coronary Artery Stenosis in Older Adults With Different Levels of Glucose Metabolism: A Real-World Retrospective Clinical StudyC反应蛋白-甘油三酯葡萄糖指数与不同糖代谢水平老年人群冠心病风险及冠状动脉狭窄严重程度的关系：一项真实世界回顾性临床研究DOI: 10.31083/RCM45886 Journal of diabetes research IF: 03.400Volume 2026, Issue No.50Effect of Nordic Walking on Anthropometrics, Glycemia, and Lipid Profile in Adults With Prediabetes or Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials北欧式健走对糖尿病前期或糖尿病患者人体测量学指标、血糖及血脂的影响：随机对照试验的系统综述与Meta分析DOI: 10.1155/jdr/5886930 Transl Androl Urol IF: 01.700Volume 14, Issue 12No.51Associations of different insulin resistance indices with the erectile dysfunction incidence: a cross-sectional analysis of the NHANES 2001-2004不同胰岛素抵抗指数与勃起功能障碍发病率的关联：基于NHANES 2001-2004的横断面分析DOI: 10.21037/tau-2025-665 Transl Androl Urol IF: 01.700Volume 14, Issue 12No.52Exploring the association between the ZJU index and overactive bladder: a cross-sectional study based on NHANES 2011-2018探索ZJU指数与膀胱过度活动症之间的关联：一项基于NHANES 2011-2018的横断面研究DOI: 10.21037/tau-2025-557 Autophagy reportsVolume 5, Issue 1No.53Glycophagy: molecular mechanisms, regulatory signals, and disease associations糖噬：分子机制、调控信号与疾病关联DOI: 10.1080/27694127.2025.2595375 Food science & nutrition IF: 03.800Volume 14, Issue 1No.54Probiotic Supplementation With Bifidobacterium longum Subsp. Longum BL21 Improves Glycemic Control and Modulates Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial补充益生菌Bifidobacterium longum subsp. longum BL21改善2型糖尿病患者血糖控制并调节肠道菌群：一项随机对照试验DOI: 10.1002/fsn3.71437 J Gastrointest Oncol IF: 02.000Volume 16, Issue 6No.55Survival outcomes of patients after liver transplantation for patients with hepatocellular carcinoma exceeding the Hangzhou criteria超出Hangzhou标准的肝细胞癌患者肝移植后的生存结局DOI: 10.21037/jgo-2025-aw-864 其他发布内容（260） More Published Articles Int J Biol Macromol IF: 08.500Ahead of Print.No.01Exploring molecular interactions of drugs in different biologically active solvents: A comprehensive review for safe and efficient drug delivery systems探索药物在不同生物活性溶剂中的分子相互作用：安全高效药物递送系统的综合评述DOI: 10.1016/j.ijbiomac.2026.150197 BMC nutrition IF: 02.200Ahead of Print.No.02Vitamin D status and cardiometabolic risk factors among hypertensive and normotensive adults: a hospital-based cross-sectional study in Nepal高血压与血压正常成人的维生素D状况及心脏代谢危险因素：尼泊尔的一项医院横断面研究DOI: 10.1186/s40795-026-01247-x BMC surgery IF: 01.800Ahead of Print.No.03Psoriasis outcomes following metabolic bariatric surgery - a systematic review of the literature代谢减重手术后银屑病转归——文献系统综述DOI: 10.1186/s12893-026-03502-1 Obesity surgery IF: 03.100Ahead of Print.No.04Mortality and Causes of Death After Metabolic Bariatric Surgery in Older Patients老年患者减重手术后的死亡率及死因分析DOI: 10.1007/s11695-026-08487-7 Pharmacological research IF: 10.500Ahead of Print.No.05The Addicted Brain: How Processed Foods Hijack Reward Pathways成瘾的大脑：加工食品如何劫持奖赏通路DOI: 10.1016/j.phrs.2026.108097 BMC medicine IF: 08.300Ahead of Print.No.06SGLT-2 Inhibitor use and liver-related and mortality outcomes in patients with type 2 diabetes and compensated cirrhosis2型糖尿病合并代偿期肝硬化患者使用SGLT-2抑制剂的肝脏相关及死亡率结局DOI: 10.1186/s12916-026-04629-x BMC health services research IF: 03.000Ahead of Print.No.07Facilitating a complex behaviour-change intervention: healthcare professionals' accounts of their journeys to competence and confidence促进一项复杂的行为改变干预：医疗专业人员对其胜任力与信心建立之路的叙述DOI: 10.1186/s12913-025-13676-8 Aging Clin Exp Res IF: 03.400Ahead of Print.No.08Prevalence and predictive factors of cognitive impairment among hospitalized older adults in iran: a cross-sectional study, 2024伊朗住院老年患者认知障碍的患病率及预测因素：一项2024年横断面研究DOI: 10.1007/s40520-025-03299-8 Nature metabolism IF: 20.800Ahead of Print.No.09AMPK at the interface of nutrient sensing, metabolic flux and energy homeostasisAMPK：营养感知、代谢通量与能量稳态的枢纽DOI: 10.1038/s42255-025-01442-3 Nature metabolism IF: 20.800Ahead of Print.No.10Single-cell-resolved transcriptional dynamics of human subcutaneous adipose tissue during lifestyle- and bariatric surgery-induced weight loss人类皮下脂肪组织在生活方式及减重手术诱导体重减轻过程中的单细胞分辨率转录动力学研究DOI: 10.1038/s42255-025-01433-4 Nature communications IF: 15.700Ahead of Print.No.11Cross-species evidence for a developmental origin of adult hypersomnia with loss of synaptic adhesion molecules beat-Ia/CADM2跨物种证据揭示成人嗜睡症的发育起源与突触黏附分子beat-Ia/CADM2缺失相关DOI: 10.1038/s41467-026-68343-1 Signal Transduct Target Ther IF: 52.700Volume 11, Issue 1No.12MAPK14 converges on key transcriptional machinery to promote vascular smooth muscle cell degeneration in abdominal aortic aneurysmMAPK14通过汇聚关键转录机制促进腹主动脉瘤中血管平滑肌细胞退化DOI: 10.1038/s41392-025-02540-0 Biol Pharm Bull IF: 01.700Volume 49, Issue 1No.13Long-Term Use of Proton Pump Inhibitors Affects Blood Levels of Indoxyl Sulfate in Japanese Patients with Chronic Kidney Disease长期使用质子泵抑制剂影响日本慢性肾脏病患者血液中硫酸吲哚酚水平DOI: 10.1248/bpb.b25-00465 Biol Pharm Bull IF: 01.700Volume 49, Issue 1No.14SMTP-44D Improves High Glucose-Induced Vascular Endothelial DysfunctionSMTP-44D改善高糖诱导的血管内皮功能障碍DOI: 10.1248/bpb.b25-00619 Genes & development IF: 07.700Ahead of Print.No.15Independent control of neurogenesis and dorsoventral patterning by NKX2-2NKX2-2独立控制神经发生与背腹侧模式形成DOI: 10.1101/gad.352886.125 BMJ open IF: 02.300Volume 16, Issue 1No.16Defining chronic ambulatory care sensitive conditions in Malaysia: a collaborative consensus study定义马来西亚慢性门诊诊疗敏感性疾病：一项共识性研究DOI: 10.1136/bmjopen-2025-099891 Physiological reviews IF: 28.700Ahead of Print.No.17Potassium channels in vascular smooth muscle cells血管平滑肌细胞中的钾离子通道DOI: 10.1152/physrev.00017.2025 Preventive medicine IF: 03.200Ahead of Print.No.18An equity audit on intervention effects of a cardiometabolic risk reduction program for women with a history of gestational diabetes in Victoria, Australia澳大利亚维多利亚州妊娠糖尿病史女性心脏代谢风险降低项目干预效果的公平性审计DOI: 10.1016/j.ypmed.2026.108509 Am J Clin Nutr IF: 06.900Ahead of Print.No.19Prediabetes, Diabetes and Folate Status among U.S. Women of Reproductive Age: National Health and Nutrition Examination Survey (NHANES) 2011-March 2020美国育龄女性的前期糖尿病、糖尿病与叶酸状态：全国健康与营养调查(NHANES) 2011年-2020年3月数据DOI: 10.1016/j.ajcnut.2026.101193 Clinical medicine : IF: 03.900Ahead of Print.No.20DIABETES: A MULTISYSTEM DISEASE NEEDING MULTI-DISCIPLINARY CARE糖尿病：一种需要多学科护理的多系统疾病DOI: 10.1016/j.clinme.2026.100554 EJCN IF: 03.900Ahead of Print.No.21Navigating comorbidity: addressing the dual burden of coronary artery disease and diabetes应对共病：管理冠状动脉疾病与糖尿病的双重负担DOI: 10.1093/eurjcn/zvaf238 Am J Physiol Gastrointest Liver Physiol IF: 03.300Ahead of Print.No.22Role of serine/threonine phosphatases 1 and 2A in pancreatic acinar fluid and electrolyte secretion丝氨酸/苏氨酸磷酸酶1和2A在胰腺腺泡液体和电解质分泌中的作用DOI: 10.1152/ajpgi.00304.2025 American journal of perinatology IF: 01.200Ahead of Print.No.23Pregnancy Outcomes in Patients with Type 1 Diabetes Using Continuous Glucose Monitoring使用连续血糖监测的1型糖尿病患者妊娠结局研究DOI: 10.1055/a-2781-7373 Nature reviews. Nephrology IF: 39.800Ahead of Print.No.24Next-generation therapeutics for diabetic kidney disease糖尿病肾病的下一代疗法DOI: 10.1038/s41581-025-01042-0 GeroScience IF: 05.400Ahead of Print.No.25Association between cardiovascular-kidney-metabolic syndrome and risks of 14 age-related health outcomes in primary prevention older population心血管-肾脏-代谢综合征与一级预防老年人群14种年龄相关健康结局风险的关联DOI: 10.1007/s11357-025-02058-x Endocrine journal IF: 02.100Ahead of Print.No.26Pituitary dysfunction in trans-sellar encephalocele: a two-case report and a literature review经蝶鞍脑膨出中的垂体功能障碍：两例报告及文献综述DOI: 10.1507/endocrj.EJ25-0480 BMJ open IF: 02.300Volume 16, Issue 1No.27Challenges in shared decision-making about major lower limb amputation: the PERCEIVE qualitative study关于大截肢共同决策面临的挑战：PERCEIVE定性研究DOI: 10.1136/bmjopen-2025-104407 Nature microbiology IF: 19.400Ahead of Print.No.28Early-life colonization by aromatic-lactate-producing bifidobacteria lowers the risk of allergic sensitization早期生命芳香乳酸产生双歧杆菌定植降低过敏致敏风险DOI: 10.1038/s41564-025-02244-9 BMJ case reports IF: 00.500Volume 19, Issue 1No.29Hypertensive crisis due to secondary aldosteronism from polyarteritis nodosa因结节性多动脉炎继发性醛固酮增多症所致的高血压危象DOI: 10.1136/bcr-2025-269055 BMC pediatrics IF: 02.000Ahead of Print.No.30Association between vitamin D status and insulin resistance in Korean adolescents: differential effects of obesity using non-insulin-based indices韩国青少年维生素D状态与胰岛素抵抗的关联：使用非胰岛素指数评估肥胖的差异效应DOI: 10.1186/s12887-026-06510-5 International journal of obesity IF: 03.800Ahead of Print.No.31Metabolic remodeling and the modulatory role of vitamin D deficiency in African American children and adolescents with obesity非裔美国儿童与青少年肥胖中的代谢重塑及维生素D缺乏的调节作用DOI: 10.1038/s41366-025-02003-0 J Vet Med Sci IF: 01.100Ahead of Print.No.32Hematological, biochemical and hormonal profiles in dogs with obesity-related metabolic disorder犬肥胖相关代谢紊乱的血常规、生化及激素特征分析DOI: 10.1292/jvms.25-0381 Molecular medicine IF: 06.400Ahead of Print.No.33Hepatic loss of AATF attenuates MASH by suppressing AKT-mTORC1 signaling and reprogramming lipid metabolism肝脏缺失AATF通过抑制AKT-mTORC1信号通路与重编程脂质代谢缓解MASHDOI: 10.1186/s10020-025-01417-w Photodiagnosis Photodyn Ther IF: 02.600Ahead of Print.No.34Association of Insulin Therapy with Diabetic Retinopathy in Type 2 Diabetes: A Cross-Sectional Analysis from the Beichen Eye Study胰岛素治疗与2型糖尿病视网膜病变的关联：基于北辰眼研究的横断面分析DOI: 10.1016/j.pdpdt.2026.105345 BMC anesthesiology IF: 02.600Ahead of Print.No.35Anaesthetic management of a pregnant woman with Brugada syndrome undergoing Caesarean section: a case report一例患有布鲁加达综合征的孕妇行剖宫产术的麻醉管理：病例报告DOI: 10.1186/s12871-025-03600-2 BMC psychology IF: 03.000Ahead of Print.No.36Psychological flexibility patterns in patients with type 2 diabetes mellitus and its associations with self-care behavior and medical condition2型糖尿病患者的心理灵活性模式及其与自我护理行为和医疗状况的关联DOI: 10.1186/s40359-025-03930-3 BMC pregnancy and childbirth IF: 02.700Ahead of Print.No.37Is gastroesophageal reflux linked to inflammation-related gestational complications and poor obstetric history?胃食管反流病是否与炎症相关性妊娠并发症及不良产科史有关？DOI: 10.1186/s12884-026-08640-1 Digestive diseases and sciences IF: 02.500Ahead of Print.No.38Impact of Type 2 Diabetes Mellitus on Liver Fibrosis and Hepatic Steatosis in Patients with Primary Biliary Cholangitis: A Longitudinal Study2型糖尿病对原发性胆汁性胆管炎患者肝纤维化和肝脂肪变性的影响：一项纵向研究DOI: 10.1007/s10620-026-09672-5 Clin Microbiol Infect IF: 08.500Ahead of Print.No.39Prevalence and clinical outcomes of RSV, COVID-19, and influenza among older hospitalized adults: The EVERY prospective cohort study老年住院成人中RSV、COVID-19及流感的患病率与临床结局：EVERY前瞻性队列研究DOI: 10.1016/j.cmi.2026.01.002 The Journal of arthroplasty IF: 03.800Ahead of Print.No.40Patients Who Have Metabolic Syndrome Have a Higher Chance of Postoperative Complications After Total Hip Arthroplasty代谢综合征患者在全髋关节置换术后发生并发症的风险更高DOI: 10.1016/j.arth.2026.01.038 CVIR IF: 02.900Ahead of Print.No.41Clinical Outcomes of Balloon-Only Venous Arterialization for Chronic Limb-Threatening Ischemia After Failed or Unfeasible Revascularization单纯球囊静脉动脉化治疗血运重建失败或不可行的慢性肢体威胁性缺血的临床结局DOI: 10.1007/s00270-025-04323-0 PloS one IF: 02.600Volume 21, Issue 1No.42Prevalence, demographic factors, co-morbidities, and treatment types associated with acanthosis nigricans in a large cross-section of 900+ transmasculine patients: Data from a single academic center 2016-2023900余名跨男性患者中黑棘皮病的患病率、人口学因素、合并症及治疗类型关联分析：基于单一学术中心2016-2023年数据DOI: 10.1371/journal.pone.0340907 PloS one IF: 02.600Volume 21, Issue 1No.43ACMTF-R: Supervised multi-omics data integration uncovering shared and distinct outcome-associated variationACMTF-R：基于监督的多组学数据整合，揭示与结果相关的共同及特异性变异DOI: 10.1371/journal.pone.0339650 A&A practice IF: 00.600Volume 19, Issue 12No.44Enhanced Ventilation Strategies in Bariatric Surgery: A Case Report of Flow-Controlled Ventilation in an Extremely Obese Patient Undergoing Robot-Assisted Bariatric Surgery减重手术中增强的通气策略：机器人辅助减重手术中一例极度肥胖患者的流量控制通气病例报告DOI: 10.1213/XAA.0000000000002111 Journal of animal science IF: 02.900Ahead of Print.No.45Overnutrition induced metabolic dysregulation and partially decreased semen quality in young beef bulls营养过剩诱导年轻肉牛代谢失调并部分降低精子质量DOI: 10.1093/jas/skag004 Food & function IF: 05.400Volume 17, Issue 1No.46Hypoglycemic effects under in vitro digestion of brewer's spent yeast β-glucan concentrate added to a rice extrudate酿酒酵母β-葡聚糖浓缩物添加于大米挤压膨化产品后的体外消化降血糖效应DOI: 10.1039/d5fo03588k Diabetes care IF: 16.600Ahead of Print.No.47Impact of Maternal Diabetes in Pregnancy on Newborn IgG Antibody Repertoire and Infection Risk in the First Six Months of Life母体孕期糖尿病对新生儿IgG抗体谱及生命前六个月感染风险的影响DOI: 10.2337/dc25-0990 Hormone research in p?diatrics : IF: 02.700Volume 99, Issue 1No.48Insulin-Induced Copeptin Response in Children and Adolescents to Diagnose Arginine Vasopressin Deficiency胰岛素诱导的和肽素反应在诊断儿童和青少年精氨酸加压素缺乏症中的应用DOI: 10.1159/000541330 Yàowù shípǐn fēnxī IF: 03.000Volume 33, Issue 4No.49Selective sodium-glucose cotransporter two inhibitor empagliflozin ameliorates diabetic cardiomyopathy by activating the AMPK/TFEB signaling pathway选择性钠-葡萄糖协同转运蛋白2抑制剂恩格列净通过激活AMPK/TFEB信号通路改善糖尿病心肌病DOI: 10.38212/2224-6614.3563 Yàowù shípǐn fēnxī IF: 03.000Volume 33, Issue 4No.50Economic evaluation of AI-assisted technologies in healthcare: A systematic review医疗健康领域AI辅助技术的经济学评价：一项系统综述DOI: 10.38212/2224-6614.3570 Brazilian Journal of Nephrology IF: 01.300Volume 48, Issue 2No.51The role of probiotics in modulating the gut microbiota as a potential inhibitor of diabetic kidney disease progression益生菌通过调节肠道菌群作为潜在抑制剂延缓糖尿病肾病进展的机制DOI: 10.1590/2175-8239-JBN-2025-0143en Annals of Internal Medicine IF: 15.200Ahead of Print.No.52Correction: Comparison of an Energy-Reduced Mediterranean Diet and Physical Activity Versus an Ad Libitum Mediterranean Diet in the Prevention of Type 2 Diabetes能量减少地中海饮食与体力活动对比自由摄取地中海饮食预防2型糖尿病的比较DOI: 10.7326/ANNALS-25-04192 Annals of Internal Medicine IF: 15.200Ahead of Print.No.53Predicting Long-Term Risk for Prostate Cancer Mortality Following a Prostate-Specific Antigen Screening Test: Prognostic Model Development and External Validation预测前列腺特异性抗原筛查后前列腺癌死亡的长期风险：预后模型的开发与外部队列验证DOI: 10.7326/ANNALS-25-02036 Natural product research IF: 01.600Ahead of Print.No.54Antitumor and in vivo antioxidant activity of 24-nor-olean-3-one-28-oic acid isolated from the roots of momordica cymbalaria (hook. F.) fenzl ex naudin in Ehrlich ascites carcinoma transplanted mice从Momordica cymbalaria根部分离的24-nor-olean-3-one-28-oic酸在艾氏腹水癌移植小鼠体内的抗肿瘤及体内抗氧化活性DOI: 10.1080/14786419.2026.2615749 ACS chemical neuroscience IF: 03.900Ahead of Print.No.55Synergistic Effect of Mutations in the Amyloidogenic Core of Human Amylin (hAM) Affords a New Potent Inhibitor of hAM Fibrillation: Computational Design and Experimental Validation人类胰淀素（hAM）淀粉样核心突变协同效应产生新型强效hAM纤维化抑制剂：计算设计与实验验证DOI: 10.1021/acschemneuro.5c00433 Neuroepidemiology IF: 04.000Ahead of Print.No.56Incidence, Prevalence, and Treatment Patterns in Chronic Inflammatory Demyelinating Polyneuropathy: Data Analysis of United States Claims慢性炎性脱髓鞘性多发性神经病的发病率、患病率及治疗模式：美国索赔数据分析DOI: 10.1159/000550418 Kidney & Blood Pressure Research IF: 02.100Ahead of Print.No.57Clinical Profile and Outcome of C3-dominant Glomerulonephritis: Retrospective studyC3优势性肾小球肾炎的临床特征与预后：一项回顾性研究DOI: 10.1159/000550422 Hormone research in p?diatrics : IF: 02.700Ahead of Print.No.58Nutrition and healthy lifestyles for children and adolescents with early-stage type 1 diabetes针对早期1型糖尿病儿童和青少年的营养与健康生活方式指导DOI: 10.1159/000550434 Eur J Endocrinol IF: 05.200Ahead of Print.No.59Quality of Life in Patients with Pheochromocytoma and Paraganglioma: Influence of Tumor Type, Genetics and Surgical Resection嗜铬细胞瘤和副神经节瘤患者的生活质量：肿瘤类型、遗传学和手术切除的影响DOI: 10.1093/ejendo/lvag003 Eur J Endocrinol IF: 05.200Ahead of Print.No.60Effects of GLP-1 Receptor Agonists on Copeptin in Euvolemic ParticipantsGLP-1受体激动剂对血容量正常参与者中肽素水平的影响DOI: 10.1093/ejendo/lvag005 J Clin Gastroenterol IF: 02.700Ahead of Print.No.61Metabolic Comorbidities and Hospital Outcomes in Patients With Inflammatory Bowel Disease: A Nationwide Analysis炎症性肠病患者的代谢合并症与住院结局：一项全国性分析DOI: 10.1097/MCG.0000000000002333 Am J Gastroenterol IF: 07.600Ahead of Print.No.62Postimaging Colorectal Cancer After Computed Tomography Colonography: A Danish Nationwide StudyCT结肠成像检查后的影像后结直肠癌：一项丹麦全国性研究DOI: 10.14309/ajg.0000000000003849 Diabetes care IF: 16.600Ahead of Print.No.63Empagliflozin in HNF1A-MODY (MODY3)-a Randomized, Double-Blind, Placebo-Controlled, Crossover Trial恩格列净在HNF1A-MODY（MODY3）中的疗效——一项随机、双盲、安慰剂对照、交叉试验DOI: 10.2337/dc25-2572 Neurology IF: 08.500Volume 106, Issue 3No.64Development of a Prognostic Model for Poststroke Dementia Using Multiple International Cohorts: A STROKOG Collaboration Study利用多国队列开发卒中后痴呆预后模型：一项STROKOG合作研究DOI: 10.1212/WNL.0000000000214574 Diabetes IF: 07.500Ahead of Print.No.65Amino Acid Sensing by the α-Cell Mitochondrial Phosphoenolpyruvate Cycle Regulates Intracellular Ca2+ Levels Without Affecting Glucagon Secretionα细胞线粒体磷酸烯醇丙酮酸循环通过感知氨基酸调节细胞内钙离子水平而不影响胰高血糖素分泌DOI: 10.2337/db25-0510 La Clinica terapeuticaVolume 177, Issue 1No.66Intelligent Monitoring of Health Conditions in Patients with Diabetes in the Context of Healthcare Digitalization医疗数字化背景下糖尿病患者的智能健康监测DOI: 10.7417/CT.2026.1981 JAMA Internal Medicine IF: 23.300Ahead of Print.No.67High-Dose vs Standard-Dose Influenza Vaccine in Older Adults With Diabetes: A Secondary Analysis of the DANFLU-2 Randomized Clinical Trial高剂量与标准剂量流感疫苗在老年糖尿病患者中的比较：DANFLU-2随机临床试验的二次分析DOI: 10.1001/jamainternmed.2025.7286 JAMA Neurology IF: 21.300Ahead of Print.No.68Maternal Pregnancy Outcomes and Offspring Risk of Adult-Onset Multiple Sclerosis母亲妊娠结局与子代成人发病型多发性硬化症风险DOI: 10.1001/jamaneurol.2025.5255 Journal of behavioral medicine IF: 02.900Ahead of Print.No.69Diabetes Distress and Glycemic Stability: The Mediating Role of Experiential Avoidance and Disordered Eating in Type 1 Diabetes糖尿病相关心理压力与血糖稳定性：经验性回避与饮食失调在1型糖尿病中的中介作用DOI: 10.1007/s10865-025-00623-5 Cell biochemistry and biophysics IF: 02.500Ahead of Print.No.70Fisetin-loaded Nanoemulsion and Fecal Microbiome Extract Enhance In Vitro Inhibition of Non-Small Cell Lung Cancer Progression负载漆黄素的纳米乳剂与粪便微生物组提取物协同提升体外实验中对非小细胞肺癌进展的抑制效果DOI: 10.1007/s12013-025-01981-2 Pituitary IF: 03.400Volume 29, Issue 1No.71The impact of growth hormone (GH) on immunosenescence: exploring the role of B and T cells生长激素对免疫衰老的影响：探索B细胞和T细胞的作用DOI: 10.1007/s11102-025-01632-y Osteoporosis international IF: 05.400Ahead of Print.No.72Non-metastatic breast cancer patients discontinuing aromatase inhibitor on denosumab: what next?停用芳香化酶抑制剂并正在使用地舒单抗的非转移性乳腺癌患者：后续如何治疗？DOI: 10.1007/s00198-025-07798-2 Osteoporosis international IF: 05.400Ahead of Print.No.73Post-fracture care and predictors of anti-osteoporotic treatment in Switzerland: a nationwide health claims analysis瑞士骨折后护理及抗骨质疏松治疗预测因素：一项全国性健康索赔数据分析DOI: 10.1007/s00198-025-07832-3 J Asian Nat Prod Res IF: 01.300Ahead of Print.No.74Methyl jasmonate protects liver and pancreas tissues of adult diabetic rats from STZ-induced oxidative stress damage茉莉酸甲酯保护成年糖尿病大鼠的肝脏和胰腺组织免受STZ诱导的氧化应激损伤DOI: 10.1080/10286020.2025.2611910 Endocrine-related cancer IF: 04.600Ahead of Print.No.75Prevalence and Clinical Characteristics of Lynch Syndrome-associated Adrenocortical Carcinoma林奇综合征相关肾上腺皮质癌的患病率与临床特征DOI: 10.1530/ERC-25-0389 Aging cell IF: 07.100Volume 25, Issue 2No.76Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage雷帕霉素通过增强对DNA损伤的抵抗力，在衰老的人类免疫系统中发挥其延缓衰老的作用DOI: 10.1111/acel.70364 Clinical toxicology IF: 03.300Ahead of Print.No.77A retrospective study of centipede bites in Guadeloupe, West Indies: epidemiology, medical and surgical management法属瓜德罗普岛蜈蚣咬伤回顾性研究：流行病学特征及内外科处理DOI: 10.1080/15563650.2025.2591338 Organic & biomolecular chemistry IF: 02.700Ahead of Print.No.78C(3)-H alkenylation of quinoxalin-2(1H)-ones with Hantzsch esters and in silico studies利用Hantzsch酯对喹喔啉-2(1H)-酮进行C(3)-H烯基化反应及计算机模拟研究DOI: 10.1039/d5ob01795e Journal of molecular histology IF: 02.200Volume 57, Issue 1No.79Combined effects of chronic high glucose and fluoride exposure on kidney cells: exploratory in vitro and in vivo study慢性高糖与氟化物暴露对肾脏细胞的联合效应：一项探索性的体外与体内研究DOI: 10.1007/s10735-025-10670-6 Archives of osteoporosis IF: 02.800Volume 21, Issue 1No.80Utility of diffusion tensor imaging for assessing bone quality in type 2 diabetes: correlation with bone turnover biomarkers扩散张量成像评估2型糖尿病骨质量的效用：与骨转换生物标志物的相关性DOI: 10.1007/s11657-025-01643-z La Clinica terapeuticaVolume 177, Issue 1No.81Determinants of Non-Adherence to the Mediterranean Diet Among Healthcare Workers: A cross-sectional study医护人员不坚持地中海饮食的决定因素：一项横断面研究DOI: 10.7417/CT.2026.1985 European journal of nutrition IF: 04.300Volume 65, Issue 1No.82Can vegetables intake pattern mediate the relationship between fast-food and cognitive performance in adolescents? The Cogni-Action project蔬菜摄入模式在快餐与青少年认知表现关系中的中介作用：Cogni-Action项目DOI: 10.1007/s00394-025-03884-7 Journal of endocrinology IF: 03.900Ahead of Print.No.83Fat's All, Folks: Culturing and Manipulating Peri-Prostatic Adipocytes to Probe Impacts on Prostate Cancer Biology脂肪的奥秘：培养与操纵前列腺周围脂肪细胞以探究其对前列腺癌生物学的影响DOI: 10.1530/JOE-25-0256 European Journal of Immunology IF: 03.700Volume 56, Issue 1No.84The Increased Secretion of Lactate Observed in Obesity and Aging Leads to the Generation of Pathogenic B Cells肥胖和衰老中观察到的乳酸分泌增加导致致病性B细胞的产生DOI: 10.1002/eji.70120 Chronobiology international IF: 01.700Ahead of Print.No.85Light matters: Investigating the influence of natural and artificial light on BMI and key mediators光线的重要性：调查自然光与人工光对BMI及其关键中介因素的影响DOI: 10.1080/07420528.2025.2606281 Cutaneous and ocular toxicology IF: 01.300Ahead of Print.No.86Alternative models for evaluation of ocular toxicological effects of environmental chemicals and pharmaceuticals: a review评估环境化学品与药物眼毒性效应的替代模型：一篇综述DOI: 10.1080/15569527.2025.2607700 Abdominal radiology IF: 02.200Ahead of Print.No.87AI for screening in healthcare: promise and challenges人工智能在医疗筛查中的应用：前景与挑战DOI: 10.1007/s00261-025-05370-4 North Carolina medical journalVolume 86, Issue 3No.88Barriers to Care in Hispanic American Patients with Diabetic Retinopathy西班牙裔美国糖尿病视网膜病变患者面临的护理障碍DOI: 10.18043/001c.143309 J Gerontol B Psychol Sci Soc Sci IF: 03.200Volume 81, Issue 2No.89Heterogeneity in Asian Americans' mortality trends, 2000-2022亚裔美国人死亡率趋势的异质性：2000-2022年DOI: 10.1093/geronb/gbaf248 Current microbiology IF: 02.600Volume 83, Issue 2No.90Green Synthesis and Bioactivity Evaluation of Silver Nanoparticles from Stevia rebaudiana and the Endophyte Aspergillus versicolor利用甜叶菊及其内生真菌泡盛曲霉绿色合成银纳米颗粒及其生物活性评估DOI: 10.1007/s00284-025-04712-1 JAMA Network Open IF: 09.700Volume 9, Issue 1No.91Volunteering and Metabolic Syndrome and Diabetes in Black Adolescents From Low-Income Families志愿服务与低收入家庭黑人青少年的代谢综合征和糖尿病DOI: 10.1001/jamanetworkopen.2025.53419 Minerva anestesiologica IF: 02.800Ahead of Print.No.92Pregabalin versus dexmedetomidine for postoperative delirium in cardiac surgery: a pragmatic step forward?普瑞巴林与右美托咪定用于心脏手术后谵妄：一项务实的进步？DOI: 10.23736/S0375-9393.25.19648-X Expert Rev Pharmacoecon Outcomes Res IF: 01.500Ahead of Print.No.93Real-world healthcare resource utilization and medical costs in patients with overweight or obesity and multimorbidity treated with semaglutide in the United States美国超重或肥胖合并多重共病患者使用司美格鲁肽的真实世界医疗资源利用与医疗成本分析DOI: 10.1080/14737167.2025.2610206 Neurological sciences IF: 02.400Volume 47, Issue 1No.94The effect of GLP-1 receptor agonists on cognition in nondiabetic patients with mild cognitive impairment or alzheimer's disease: a meta-analysis of randomized controlled trialsGLP-1受体激动剂对非糖尿病轻度认知障碍或阿尔茨海默病患者认知功能影响的荟萃分析DOI: 10.1007/s10072-025-08602-z Tremor Other Hyperkinet Mov (N Y) IF: 02.100Volume 16, Issue No.95Proceedings of the 12(th) International Meeting on Neuroacanthocytosis, Cohen Syndrome, and Other VPS13-Related Disorders第12届神经棘红细胞增多症、Cohen综合征及其他VPS13相关疾病国际会议纪要DOI: 10.5334/tohm.1124 Drugs - real world outcomes IF: 01.900Ahead of Print.No.96Trends in Adverse Event Reports of Dipeptidyl Peptidase-4 Inhibitor-Associated Pemphigoid in Japan日本二肽基肽酶-4抑制剂相关性天疱疮不良事件报告趋势DOI: 10.1007/s40801-025-00535-5 J Cardiovasc Med IF: 02.000Ahead of Print.No.97Hypokinetic nondilated cardiomyopathy: clinical characteristics, prognosis, and therapy response compared to dilated cardiomyopathy相比扩张型心肌病，非扩张性低动力性心肌病的临床特征、预后和治疗反应DOI: 10.2459/JCM.0000000000001813 La Clinica terapeuticaVolume 177, Issue 1No.98Metabolic and Hormonal Impact of Subclinical Hypothyroidism in Women with Polycystic Ovary Syndrome: A Cross-Sectional Study from South India印度南部多囊卵巢综合征女性中亚临床甲状腺功能减退症的代谢与激素影响：一项横断面研究DOI: 10.7417/CT.2026.1983 Am J Physiol Cell Physiol IF: 04.700Ahead of Print.No.99Ablation of Tumor-Derived IGFBP-3 Attenuates Cancer-Associated Skeletal Muscle Wasting in Murine Pancreatic Cancer敲除肿瘤来源的IGFBP-3可减轻小鼠胰腺癌相关的骨骼肌消耗DOI: 10.1152/ajpcell.00421.2025 Diabetes IF: 07.500Ahead of Print.No.100GLP-1, Pancreatic β-Cells, and Insulin Secretion: What We Know and Where We Need to GoGLP-1、胰腺β细胞与胰岛素分泌：已知与待探索DOI: 10.2337/db25-0695 Diabetes IF: 07.500Ahead of Print.No.101Identifying Insulin Autoantibodies With Differential Risk in Type 1 Diabetes With a Novel Bridging ELISA利用新型桥接酶联免疫吸附法鉴定具有不同风险的1型糖尿病胰岛素自身抗体DOI: 10.2337/db25-0696 Pituitary IF: 03.400Volume 29, Issue 1No.102Comparison of oral versus intravenous glucose exposure on plasma growth hormone levels: a crossover study in healthy volunteers口服与静脉葡萄糖暴露对血浆生长激素水平的比较：一项健康志愿者的交叉研究DOI: 10.1007/s11102-025-01633-x Molecular neurobiology IF: 04.300Volume 63, Issue 1No.103Valacyclovir Mitigates Amyloid Plaque Deposition, P-Tau Aggregation, and Neuroinflammation in Streptozotocin induced Alzheimer's Disease Rat Model伐昔洛韦减轻链脲佐菌素诱导的阿尔茨海默病大鼠模型中的淀粉样斑块沉积、p-Tau聚集及神经炎症DOI: 10.1007/s12035-025-05652-4 Nutrition reviews IF: 04.900Ahead of Print.No.104The Effects of Probiotic Supplementation on Bisphenol A Toxicity: A Systematic Literature Review益生菌补充对双酚A毒性的影响：一项系统文献综述DOI: 10.1093/nutrit/nuaf272 Adv Clin Exp Med IF: 01.900Ahead of Print.No.105Simple, low-cost in vitro protocol for differentiating mesenchymal stem cells into cardiomyocyte-like cells将间充质干细胞分化为心肌细胞样细胞的简单、低成本体外方案DOI: 10.17219/acem/204112 J Am Nutr Assoc IF: 02.600Ahead of Print.No.106Effects of Brassica juncea Seed Extract on Diabetes-Related Gene Expression Profiling of Pancreatic β-Cells in a Rat Model: Relevance to Environmental and Health Safety芥菜籽提取物对大鼠模型胰腺β细胞糖尿病相关基因表达谱的影响：与环境和健康安全的相关性DOI: 10.1080/27697061.2025.2596999 Zh Nevrol Psikhiatr Im S S KorsakovaVolume 125, Issue 12No.107[Relationship of glycemic, metabolic, immuno-inflammatory, and psychopathological parameters in patients with depressive disorder: a retrospective analysis]抑郁障碍患者血糖、代谢、免疫炎症及精神病理参数的相关性：一项回顾性分析DOI: 10.17116/jnevro2025125121223 Biologie aujourd'huiVolume 219, Issue 3-4No.108[Popular myths vs. physiological realities: The rehabilitation of lactate]流行误解 vs. 生理现实：乳酸的平反DOI: 10.1051/jbio/2025010 Am J Med Qual IF: 01.300Ahead of Print.No.109Determining Causes of Insulin-Induced Hypoglycemia Using an Electronic-Based Trigger使用电子触发器确定胰岛素诱导低血糖的原因DOI: 10.1097/JMQ.0000000000000280 World J Exp MedVolume 15, Issue 3No.110Clinical significance of differential plasma proteins levels in the diagnosis of epithelial ovarian cancer差异血浆蛋白水平在上皮性卵巢癌诊断中的临床意义DOI: 10.5493/wjem.v15.i3.107711 FASEB bioAdvances IF: 02.000Volume 8, Issue 1No.111The Gut Microbiota-Insulin Resistance Axis: Mechanisms, Clinical Implications, and Therapeutic Potential肠道菌群-胰岛素抵抗轴：机制、临床意义与治疗潜力DOI: 10.1096/fba.2025-00218 Translational sports medicineVolume 2026, Issue No.112Associations Between Handgrip Strength and Markers of Insulin Resistance and Inflammation in Childhood and Adolescence: A Systematic Review With Meta-Analysis儿童青少年握力与胰岛素抵抗及炎症标志物关联性：系统综述与荟萃分析DOI: 10.1155/tsm2/1091342 Diabetes spectrumVolume 38, Issue 5No.113Racial Disparities in the Use of Automated Insulin Delivery Systems in Youth With Type 1 Diabetes青少年1型糖尿病患者中自动胰岛素输送系统使用的种族差异DOI: 10.2337/ds25-0023 Diabetes spectrumVolume 38, Issue 5No.114Observations of Glucagon-Prescribing Patterns for High-Risk People With Diabetes Within a Federally Qualified Health Center在一家联邦合格医疗中心内对高风险糖尿病患者胰高血糖素处方模式的观察DOI: 10.2337/ds25-0044 Diabetes spectrumVolume 38, Issue 5No.115Factors Considered Important by Diabetes Providers Before Recommending Automated Insulin Delivery Systems: Observations From the T1D Exchange Quality Improvement Collaborative糖尿病提供者在推荐自动胰岛素输送系统前考虑的重要因素：来自T1D Exchange质量改进协作组的观察DOI: 10.2337/ds25-0009 Case reports in nephrologyVolume 2026, Issue No.116A Case of Post-Transplantation Lymphoproliferative Disorder Following Kidney Transplantation肾移植后移植后淋巴组织增生性疾病一例DOI: 10.1155/crin/5917161 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.117The spectrum of exogenous insulin requirement in people living with type 1 diabetes: A cross-sectional analysis1型糖尿病患者外源性胰岛素需求谱：一项横断面分析DOI: 10.1111/dom.70467 Diabetes, obesity & metabolism IF: 05.700Ahead of Print.No.118Long-acting insulin analogues and the risk of diabetic nephropathy among patients with type 2 diabetes: A population-based cohort study长效胰岛素类似物与2型糖尿病患者糖尿病肾病风险：一项基于人群的队列研究DOI: 10.1111/dom.70397 Development IF: 03.600Ahead of Print.No.119Pre-dauer starvation rapidly and reversibly reduces niche proliferative signaling to the C. elegans germ line前滞育期饥饿快速且可逆地降低秀丽隐杆线虫生殖系的微环境增殖信号DOI: 10.1242/dev.204972 JCRPE IF: 01.500Ahead of Print.No.120The Relationship Between HbA1c and GMI and Glucose Metrics in Children and Adolescents with Type 1 Diabetes Using AID儿童与青少年1型糖尿病患者使用自动化胰岛素输注系统时HbA1c、GMI与血糖指标间的关系DOI: 10.4274/jcrpe.galenos.2025.2025-10-11 Journal of materials chemistry IF: 05.700Ahead of Print.No.121Surfactin-inspired arginine- and lysine-rich peptides inhibit human insulin aggregation and prevent amyloid-induced cytotoxicity受表面活性素启发的富含精氨酸与赖氨酸多肽抑制人胰岛素聚集并防止淀粉样蛋白诱导的细胞毒性DOI: 10.1039/d5tb01952d Endocrinol Diabetes Metab IF: 02.600Volume 9, Issue 1No.122Serum Uric Acid as a Mediator of Insulin Resistance: Molecular Mechanisms and Metabolic Pathways血清尿酸：胰岛素抵抗的潜在介导者及其分子机制与代谢通路DOI: 10.1002/edm2.70163 Nursing standardAhead of Print.No.123Recognising, managing and reducing the risk of hypoglycaemia in adults with diabetes成人糖尿病患者低血糖风险的识别、管理与降低DOI: 10.7748/ns.2026.e12574 J Clin Endocrinol Metab IF: 05.100Ahead of Print.No.124Insulin Receptor Family Autoantibodies in Patients with Type B insulin ResistanceB型胰岛素抵抗患者的胰岛素受体家族自身抗体DOI: 10.1210/clinem/dgaf692 Ther Adv Psychopharmacol IF: 04.000Volume 16, Issue No.125A description of antipsychotic prescribing patterns on the inpatient behavioral health setting: a multicenter cross-sectional analysis住院行为健康环境中抗精神病药物处方模式的描述：一项多中心横断面分析DOI: 10.1177/20451253251394296 World J Exp MedVolume 15, Issue 3No.126Effect of propolis and honey in hyperglycemia-induced kidney and liver injuries, proteinuria, and oxidant and antioxidant parameters蜂胶与蜂蜜对高血糖所致肾肝损伤、蛋白尿及氧化与抗氧化参数的影响DOI: 10.5493/wjem.v15.i3.99330 World J Exp MedVolume 15, Issue 3No.127Relationship of diabetes mellitus with prognostic factors in breast cancer糖尿病与乳腺癌预后因素的关系DOI: 10.5493/wjem.v15.i3.108318 Int J Endocrinol IF: 02.300Volume 2026, Issue No.128Correction to "Astaxanthin Modulates Inflammation in Type 2 Diabetes via Regulation of microRNAs, Lysophosphatidylcholine, and α-Hydroxybutyrate"《虾青素通过调控微小RNA、溶血磷脂酰胆碱和α-羟基丁酸调节2型糖尿病炎症》一文更正DOI: 10.1155/ije/9845896 Ther Adv Endocrinol Metab IF: 04.600Volume 17, Issue No.129Accuracy and feasibility of real-time continuous glucose monitoring in early postoperative intensive care after liver transplantation肝移植术后早期重症监护中实时连续血糖监测的准确性与可行性DOI: 10.1177/20420188251405372 Curēus IF: 01.300Volume 17, Issue 12No.130Shewanella algae as a Rare Cause of Bullous Cellulitis and Sepsis: The First Reported Case in Lithuania希瓦氏藻作为大疱性蜂窝织炎和脓毒症的罕见病因：立陶宛首例报告病例DOI: 10.7759/cureus.98958 Curēus IF: 01.300Volume 17, Issue 12No.131A Rare Case of Parathyroid Carcinoma Initially Misdiagnosed as a Parathyroid Adenoma一例最初被误诊为甲状旁腺腺瘤的罕见甲状旁腺癌病例DOI: 10.7759/cureus.98794 Curēus IF: 01.300Volume 17, Issue 12No.132Impact of Long-Term Glucocorticoid Therapy on the Response to Biologic Agents in Rheumatoid Arthritis: A Prospective Observational Study长期糖皮质激素治疗对类风湿关节炎生物制剂疗效的影响：一项前瞻性观察研究DOI: 10.7759/cureus.98824 Curēus IF: 01.300Volume 17, Issue 12No.133Functional Magnetic Resonance Imaging (fMRI) and Music Therapy for Concussion: A Case Report功能性磁共振成像与音乐疗法治疗脑震荡：一例病例报告DOI: 10.7759/cureus.98823 Curēus IF: 01.300Volume 17, Issue 12No.134Neutrophil-to-Lymphocyte Ratio Correlation With the Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery (SYNTAX) Score in Patients With Non-ST-Segment Elevation Acute Coronary Syndrome中性粒细胞与淋巴细胞比值与非ST段抬高型急性冠状动脉综合征患者SYNTAX评分的相关性DOI: 10.7759/cureus.98890 Curēus IF: 01.300Volume 17, Issue 12No.135Outcomes of Free Flap Surgery in Head and Neck Cancer Patients With Chronic Kidney Disease: A Single-Institution Retrospective Study of 61 Cases慢性肾脏病头颈癌患者游离皮瓣手术结局：61例单中心回顾性研究DOI: 10.7759/cureus.98897 Curēus IF: 01.300Volume 17, Issue 12No.136Atypical Presentation of Chronic Left Anterior Descending Occlusion: Heart Failure Without Angina as the Initial Manifestation慢性左前降支闭塞的不典型表现：心力衰竭作为首发症状而无心绞痛DOI: 10.7759/cureus.98903 Curēus IF: 01.300Volume 17, Issue 12No.137Late-Onset NR0B1-Related Adrenal Hypoplasia Congenita Presenting With Primary Adrenal Insufficiency and Pubertal Delay表现为原发性肾上腺皮质功能减退症和青春期延迟的迟发性NR0B1相关性先天性肾上腺发育不全DOI: 10.7759/cureus.98859 Indian J Radiol ImagingVolume 36, Issue 1No.138Spectrum of Typical and Atypical Imaging Findings and Pathological Features in Diabetic Mastopathy糖尿病性乳腺病的典型与非典型影像学表现及病理特征的谱系分析DOI: 10.1055/s-0045-1808258 J Curr Glaucoma PractVolume 19, Issue 4No.139The Influence of Hemodialysis on Ocular Pressure Dynamics: An Observational Study on IOP and OPP Changes血液透析对眼压动态的影响：一项关于IOP和OPP变化的观察性研究DOI: 10.5005/jp-journals-10078-1497 J Curr Glaucoma PractVolume 19, Issue 4No.140Glaucoma Risk Reduction as a Secondary Benefit of Glucagon-like Peptide-1 Receptor Agonists: A Review of Emerging Evidence胰高血糖素样肽-1受体激动剂降低青光眼风险作为次要获益：新兴证据综述DOI: 10.5005/jp-journals-10078-1501 Am J Lifestyle Med IF: 01.300Ahead of Print.No.141Lifestyle Interventions for Major Depressive Disorder (MDD): An Expert Consensus Statement From the American College of Lifestyle Medicine生活方式干预治疗重性抑郁障碍（MDD）：来自美国生活方式医学会的专家共识声明DOI: 10.1177/15598276251408353 F1000ResearchVolume 13, Issue No.142Molecular Characterization of Dermatophyte species from rural tertiary care hospital: A Study Protocol农村三级医院皮肤癣菌的分子特征研究：一项研究方案DOI: 10.12688/f1000research.141657.4 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.143A Study to Asses Effects of Diabetes Mellitus on Treatment Outcome of Tuberculosis Patients一项评估糖尿病对结核病患者治疗结局影响的研究DOI: 10.4103/jpbs.jpbs_1425_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.144Correlation of Candida Species and Carriage in Uncontrolled and Controlled Diabetics on Various Oral Hypoglycemic Drug Regimen不同口服降糖药方案下控制与非控制糖尿病患者口腔念珠菌定植及其菌种相关性研究DOI: 10.4103/jpbs.jpbs_1372_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.145Awareness, Perception, and Knowledge about Oral Microbiota among College of Dentistry Students in Gulf Medical University/United Arab Emirates阿拉伯联合酋长国海湾医科大学牙科学院学生对口腔微生物群的认知、理解及知识现状DOI: 10.4103/jpbs.jpbs_1161_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.146Comparison of Extraction Socket Healing in Patients with Type 2 Diabetes on Oral Hypoglycemics Versus Nondiabetic-Original Research口服降糖药治疗的2型糖尿病患者与非糖尿病患者拔牙创愈合情况比较DOI: 10.4103/jpbs.jpbs_1240_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.147Periodontal Status of Medically Compromised Patients Visiting Teaching Hospitals in Riyadh City: A Retrospective Study利雅得市教学医院就诊的全身性疾病患者的牙周状况：一项回顾性研究DOI: 10.4103/jpbs.jpbs_1269_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.148Association Between Serum Vitamin D Levels and Glycemic Status in Prediabetic Adults糖尿病前期成人血清维生素D水平与血糖状态之间的关联DOI: 10.4103/jpbs.jpbs_1112_25 Ther Adv Drug Saf IF: 03.400Volume 17, Issue No.149Safety and risk management in clinical trials for chronic wounds with tissue regenerative products使用组织再生产品的慢性伤口临床试验中的安全性与风险管理DOI: 10.1177/20420986251385861 JBMR plus IF: 02.400Volume 10, Issue 2No.150Denosumab as a treatment for pediatric hypercalcemia-a multicenter experienceDenosumab作为儿童高钙血症的治疗：一项多中心经验DOI: 10.1093/jbmrpl/ziaf171 J Educ Teach Emerg MedVolume 10, Issue 5No.151Managing Conflict Case: Admission of a Patient with Decompensated Schizophrenia, Hypertension, and Diabetes冲突管理案例：一例失代偿性精神分裂症、高血压和糖尿病患者入院争议的化解DOI: 10.21980/J8.52341 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue 4No.152Spectrum of Deep Neck Space Abscesses: A Case Series Experience in a Tertiary Health Care Centre深颈部间隙脓肿类型谱：一家三级医疗中心的病例系列经验DOI: 10.4103/jpbs.jpbs_1490_25 Int J Biol Sci IF: 10.000Volume 22, Issue 2No.153Impact of rare JAK/STAT germline mutations on vaccination-induced innate immune responses in a Tyrolian population罕见JAK/STAT种系突变对蒂罗尔人群疫苗接种诱导先天免疫应答的影响DOI: 10.7150/ijbs.124098 Plastic surgery IF: 00.600Ahead of Print.No.154Treatment of Critical Hand Ischemia Due to Mycotic Aneurysm of Radial and Ulnar Arteries: A Case Report桡动脉与尺动脉真菌性动脉瘤所致危重手部缺血的治疗：病例报告DOI: 10.1177/22925503251411863 Journal of diabetes research IF: 03.400Volume 2026, Issue No.155Association Between Sodium-Glucose Cotransporter-2 Inhibitors and Sepsis Risk in Patients With Type 2 Diabetes Mellitus钠-葡萄糖协同转运蛋白2抑制剂与2型糖尿病患者脓毒症风险的相关性研究DOI: 10.1155/jdr/1437417 Curēus IF: 01.300Volume 17, Issue 12No.156Lifestyle Behavioral Self-Care Practices and Their Determinants Among Type 2 Diabetes Patients Attending a Non-communicable Disease Clinic in Agra District: A Cross-Sectional Study印度阿格拉地区非传染性疾病诊所2型糖尿病患者的生活方式行为自我护理实践及其决定因素：一项横断面研究DOI: 10.7759/cureus.98857 Avicenna J Med BiotechnolVolume 17, Issue 3No.157Ameliorating Potential of Quercetin and Curcumin on Glucose-6-Phosphate Dehydrogenase Expression via miRNAs in Rats with Type 2 Diabetes Mellitus槲皮素与姜黄素通过miRNAs改善2型糖尿病大鼠葡萄糖-6-磷酸脱氢酶表达的潜力DOI: 10.18502/ajmb.v17i3.19280 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.158Evaluation of Hematological Changes in Type 2 Diabetes Mellitus and Their Correlation with Glycemic Control评估2型糖尿病患者的血液学变化及其与血糖控制的相关性DOI: 10.4103/jpbs.jpbs_1111_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.159A Cross-sectional Study of Awareness about Diabetes Mellitus and its Complications among Indian Patients with Type 2 Diabetes Mellitus印度2型糖尿病患者对糖尿病及其并发症认知度的横断面研究DOI: 10.4103/jpbs.jpbs_1417_25 J Diabetes Metab Disord IF: 01.600Volume 25, Issue 1No.160Genetic susceptibility to type 2 diabetes: Insights from a comprehensive meta-analysis of FABP2 polymorphisms2型糖尿病的遗传易感性：基于FABP2基因多态性的全面荟萃分析启示DOI: 10.1007/s40200-025-01847-7 J Diabetes Metab Disord IF: 01.600Volume 25, Issue 1No.161GLP-1 receptor agonists in kidney transplant recipients with type 2 diabetes mellitus: a systematic review and meta-analysis on mortality and major adverse kidney eventsGLP-1受体激动剂在合并2型糖尿病的肾移植受者中的应用：一项关于死亡率和主要不良肾脏事件的系统综述与荟萃分析DOI: 10.1007/s40200-025-01801-7 Aging cell IF: 07.100Volume 25, Issue 2No.162Frequently Reported Blood Biomarkers in Sarcopenia Clinical Trials: A Systematic Review and Meta-Analysis肌肉减少症临床试验中常报告的血源性生物标志物：一项系统综述与荟萃分析DOI: 10.1111/acel.70361 Curēus IF: 01.300Volume 18, Issue 1No.163Sight Unseen: Glucagon-Like Peptide-1 (GLP-1) Agonism Therapy and Nonarteritic Anterior Ischemic Optic Neuropathy视而不见：胰高血糖素样肽-1（GLP-1）激动剂治疗与非动脉炎性前部缺血性视神经病变DOI: 10.7759/cureus.100953 NPJ biomedical innovationsVolume 3, Issue 1No.164Decoding wound healing: cellular insights and technological advances解码伤口愈合：细胞见解与技术进展DOI: 10.1038/s44385-025-00046-6 Curēus IF: 01.300Volume 17, Issue 12No.165Panhypopituitarism Secondary to a Central Nervous System Germinoma继发于中枢神经系统生殖细胞瘤的全垂体功能减退症DOI: 10.7759/cureus.98887 Scientifica IF: 03.100Volume 2025, Issue No.166Characterization of Unsaponifiable Matter in Unripe Pistacia atlantica Fruits: Evaluation of Antioxidant Activity and α-Amylase Inhibitory Effect未成熟大西洋黄连木果实中不皂化物的表征：抗氧化活性与α-淀粉酶抑制效应评估DOI: 10.1155/sci5/8016775 NAR molecular medicineVolume 3, Issue 1No.167Combination of vemurafenib, pleconaril, and AG7404 attenuates enterovirus replication in vitro and in vivo维莫非尼、普莱康纳利与AG7404三联疗法在体外和体内抑制肠道病毒复制DOI: 10.1093/narmme/ugaf046 J Gastrointest Oncol IF: 02.000Volume 16, Issue 6No.168Hypercalcemia in metastatic pancreatic neuroendocrine tumor: a case report of ectopic 1,25 hydroxyvitamin D production by tumor cells and tumor-associated macrophages转移性胰腺神经内分泌肿瘤致高钙血症一例：肿瘤细胞与肿瘤相关巨噬细胞的1,25二羟基维生素D异位生成DOI: 10.21037/jgo-2025-616 Curēus IF: 01.300Volume 18, Issue 1No.169Comparative Effectiveness of Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitors Versus Glucagon-Like Peptide-1 (GLP-1) Agonists on Cardiovascular and Renal Outcomes in Type 2 Diabetes: A Systematic Review and Network Meta-Analysis钠-葡萄糖协同转运蛋白2抑制剂与胰高血糖素样肽-1受体激动剂对2型糖尿病患者心血管及肾脏结局的疗效比较：一项系统综述与网络荟萃分析DOI: 10.7759/cureus.100927 Dermatol Res Pract IF: 01.900Volume 2026, Issue No.170Prurigo Pigmentosa Following Bariatric Surgery: A Comprehensive Clinicopathological Review减重手术后发生的色素性痒疹：一项综合临床病理学回顾DOI: 10.1155/drp/1993385 Diabetes spectrumVolume 38, Issue 5No.171Population Screening for Type 1 Diabetes in Pediatrics via Well-Child Visits: Barriers and Facilitators to Implementation通过儿童健康体检进行儿科1型糖尿病普遍筛查：实施障碍与促进因素DOI: 10.2337/ds25-0036 Diabetes spectrumVolume 38, Issue 5No.172Psychological Impact of Type 1 Diabetes: A Focus on Disordered Eating Behavior in Female Adolescents1型糖尿病的心理影响：聚焦女性青少年的饮食失调行为DOI: 10.2337/ds25-0001 Pediatric allergy and immunology IF: 04.500Volume 37, Issue 1No.173Food protein-induced enterocolitis syndrome in children: A swiss prospective multicenter study儿童食物蛋白诱导性肠炎综合征：一项瑞士前瞻性多中心研究DOI: 10.1111/pai.70279 Int J Ophthalmol IF: 01.800Volume 19, Issue 1No.174Intraocular inflammation after intravitreal injection of faricimab-a case series including one case of bilateral choroidal involvement玻璃体内注射法瑞西单抗后的眼内炎症——包含一例双侧脉络膜受累的病例系列DOI: 10.18240/ijo.2026.01.23 Int J Ophthalmol IF: 01.800Volume 19, Issue 1No.175Management of coexisting cataract and diabetic macular edema: a comparative study of dexamethasone implant versus anti-VEGF agents injections合并白内障与糖尿病性黄斑水肿的治疗：地塞米松植入剂对比抗VEGF药物注射的比较研究DOI: 10.18240/ijo.2026.01.07 Malaysian family physicianVolume 20, Issue No.176A scoping review of digital health applications for managing noncommunicable diseases in primary care post-pandemic: Lessons from the Western Pacific Region大流行后初级保健中非传染性疾病管理的数字健康应用范围综述：来自西太平洋地区的经验DOI: 10.51866/rv.919 Circulation reports IF: 01.100Volume 8, Issue 1No.177Pulse Rate Variability and All-Cause Mortality Risk in the General Japanese Population脉率变异性与日本一般人群全因死亡风险DOI: 10.1253/circrep.CR-25-0193 Plast Reconstr Surg Glob Open IF: 01.800Volume 14, Issue 1No.178Perineal Verrucous Carcinoma Associated With Hypercalcemia: First Clinical Report of Parathyroid Hormone-Related Protein-producing Tumor与高钙血症相关的会阴部疣状癌：甲状旁腺激素相关蛋白产生性肿瘤的临床报告DOI: 10.1097/GOX.0000000000007395 Health science reports IF: 02.100Volume 9, Issue 1No.179The Role of Health-Related Factors in the Prevalence and Severity of COVID-19: A Retrospective Cohort Study Based on Sabzevar Persian Cohort Data健康相关因素在COVID-19患病率和严重程度中的作用：基于Sabzevar波斯队列数据的回顾性队列研究DOI: 10.1002/hsr2.71709 Expert opinion on drug delivery IF: 05.400Ahead of Print.No.180Application of iron oxide nanoparticles in liver drug delivery: insights into biodegradation and toxicity at cellular, tissue, and organ levels铁氧化物纳米颗粒在肝脏药物递送中的应用：从细胞、组织到器官层面的生物降解与毒性见解DOI: 10.1080/17425247.2026.2613932 RC IF: 01.300Volume 26, Issue 12No.181The Beneficial Effects of Glucagon-Like Peptide-1 Agonists on Blood Pressure: A Comprehensive Review胰高血糖素样肽-1受体激动剂对血压的有益影响：全面综述DOI: 10.31083/RCM45204 Korean J Community NutrVolume 28, Issue 6No.182[Process evaluation of a mobile healthcare program among employees with overweight and obesity: a 12-week intervention study investigating the role of engagement]超重和肥胖员工移动健康计划的过程评估：一项探讨参与度作用的12周干预研究DOI: 10.5720/kjcn.2023.28.6.466 Obesity science & practice IF: 01.900Volume 12, Issue 1No.183A Cross-Sectional Study Investigating the Relationship Between the FTO Gene Polymorphism in Relation to Obesity Traits and Vitamin D Status in AdolescenceFTO基因多态性与青少年肥胖特征及维生素D状态关系的横断面研究DOI: 10.1002/osp4.70112 Korean J Community NutrVolume 28, Issue 2No.184Changes in dietary habits and chronic diseases before and after COVID-19 by regions using data from the 2018-2020 Korea Community Health Survey and Consumer Behavior Survey for Foods: a cross-sectional study基于韩国社区健康调查与食品消费行为调查数据：COVID-19前后不同地区饮食习惯与慢性疾病的变化DOI: 10.5720/kjcn.2023.28.2.124 Korean J Community NutrVolume 28, Issue 2No.185Effectiveness of a mobile health intervention on weight loss and dietary behavior changes among employees with overweight and obesity: a 12-week intervention study investigating the role of engagement移动健康干预对超重肥胖员工体重减轻及饮食行为改变的效果：一项为期12周的干预研究探究参与度作用DOI: 10.5720/kjcn.2023.28.2.141 World J Exp MedVolume 15, Issue 3No.186Glucagon-like peptide and its receptor agonists for the treatment of rheumatic diseases胰高血糖素样肽-1及其受体激动剂用于治疗风湿性疾病DOI: 10.5493/wjem.v15.i3.107020 World J Exp MedVolume 15, Issue 3No.187Potential role of nanopharmacology in reducing neuroinflammation associated with hypertension and metabolic disorders纳米药理学在减轻高血压与代谢紊乱相关神经炎症中的潜在作用DOI: 10.5493/wjem.v15.i3.106743 Int J Nephrol IF: 01.400Volume 2026, Issue No.188Chronic Kidney Disease and Superimposed Acute Kidney Injury: Greater Impact of Acute Insults on Outcomes慢性肾脏病与并发急性肾损伤：急性打击对结局影响更甚DOI: 10.1155/ijne/1353892 Food Science and Biotechnology IF: 03.100Volume 35, Issue 1No.189Anti-obesity effect of Bifidobacterium adolescentis SPM2022, isolated from Korean adult来自韩国成人的青春双歧杆菌SPM2022的抗肥胖效应DOI: 10.1007/s10068-025-02013-8 JB & JS open access IF: 03.800Volume 11, Issue 1No.190Weight and Infantile Blount Disease: Insights from a Rural Ghanaian Cohort体重与婴儿布朗特病：来自加纳农村队列的启示DOI: 10.2106/JBJS.OA.25.00310 Curēus IF: 01.300Volume 17, Issue 12No.191Measuring Adipocytokines in Young Patients With Type 2 Diabetes Presenting to a Tertiary Care Centre in Upper Assam, India测量印度上阿萨姆地区三级医疗中心就诊的年轻2型糖尿病患者的脂肪细胞因子DOI: 10.7759/cureus.98779 Curēus IF: 01.300Volume 17, Issue 12No.192Severe Small-Bowel Obstruction in a High-Risk Patient on Long-Term Tirzepatide Therapy: A Case Report长期替尔泊肽治疗的高风险患者发生严重小肠梗阻：病例报告DOI: 10.7759/cureus.98935 Curēus IF: 01.300Volume 17, Issue 12No.193Revisiting Jenkins' Rule: Evidence-Based Insights on the Suture-to-Wound Length Ratio and Wound Dehiscence重温Jenkins规则：关于缝线长度与伤口长度比例及伤口裂开的循证见解DOI: 10.7759/cureus.98942 Curēus IF: 01.300Volume 17, Issue 12No.194Ulcer Perforation on Excluded Stomach Following Gastric Bypass Surgery: A Case Report of Atypical Presentation Without Pneumoperitoneum胃旁路术后胃囊袋溃疡穿孔：一例无气腹不典型表现病例报告DOI: 10.7759/cureus.98785 Curēus IF: 01.300Volume 17, Issue 12No.195Pregnancy After Bariatric Surgery: Hepatobiliary Implications, Maternal Outcomes, and Clinical Considerations减重手术后妊娠：肝胆影响、母体结局与临床考量DOI: 10.7759/cureus.98939 Curēus IF: 01.300Volume 17, Issue 12No.196Common Risk Factors Associated With Chronic Kidney Disease in Sudan: A Pilot Study苏丹慢性肾脏病常见相关危险因素：一项初步研究DOI: 10.7759/cureus.98780 Curēus IF: 01.300Volume 17, Issue 12No.197Early-Onset Type 2 Diabetes: A Comprehensive Review From Adolescence to Adulthood早发性2型糖尿病：从青少年到成年的全面综述DOI: 10.7759/cureus.98896 Curēus IF: 01.300Volume 17, Issue 12No.198Non-dysraphic Thoracic Spinal Lipoma in an Obese Adult Woman: A Case Report一例肥胖成年女性的非脊柱闭合不全性胸椎脂肪瘤病例报告DOI: 10.7759/cureus.98832 Avicenna J Med BiotechnolVolume 17, Issue 3No.199The Quality and Quantity of Nanoparticles Extracted from Human Adipose Tissue Derived-Mesenchymal Stem Cells从人脂肪组织来源间充质干细胞提取的纳米颗粒质量与数量研究DOI: 10.18502/ajmb.v17i3.19277 Food science & nutrition IF: 03.800Volume 14, Issue 1No.200Fermented Rice Bran: A Promising Therapeutic Agent Against High-Fat Diet-Induced Metabolic Disorders发酵米糠：一种对抗高脂饮食诱导代谢紊乱的有前景的治疗剂DOI: 10.1002/fsn3.71439 Food science & nutrition IF: 03.800Volume 14, Issue 1No.201Effects of Non-Soy Legumes on Body Weight and Body Composition: A Systematic Review and Meta-Analysis of Randomized Controlled Trials非大豆类豆科植物对体重及身体成分的影响：一项随机对照试验的系统综述与荟萃分析DOI: 10.1002/fsn3.71365 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.202Prevalence of Nonalcoholic Fatty Liver Disease in Obese Patients and its Association with Insulin Resistance Markers肥胖患者中非酒精性脂肪肝病的患病率及其与胰岛素抵抗标志物的关联DOI: 10.4103/jpbs.jpbs_1456_25 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.203Assessing Knowledge, Attitude, Practices (KAP), Lifestyle Diseases, and Psychological Well-Being among Commercial Vehicle Drivers in Central India印度中部商用车司机的知识、态度、行为、生活方式疾病及心理福祉评估DOI: 10.4103/jpbs.jpbs_1275_25 Frontiers in nutrition IF: 05.100Volume 12, Issue No.204South Asia-specific adaptation of Mediterranean diet principles: a mixed-methods review for practical and sustainable dietary habits南亚特定地中海饮食原则适配：一项关于实用与可持续饮食习惯的混合方法综述DOI: 10.3389/fnut.2025.1719686 Korean J Community NutrVolume 28, Issue 1No.205Nutritional status and dietary behavior of North Korean adolescent refugees based on Nutrition Quotient for Korean adolescents: a preliminary study基于韩国青少年营养商数的朝鲜青少年难民营养状况与饮食行为初步研究DOI: 10.5720/kjcn.2023.28.1.1 DEN open IF: 01.500Volume 6, Issue 1No.206Efficacy and Safety of a Revised Gastric Peroral Endoscopic Myo-Neurotomy Procedure for Bariatric Endoscopy in a Porcine Model改良胃经口内镜下肌神经切断术用于减重内镜治疗在猪模型中的有效性与安全性研究DOI: 10.1002/deo2.70230 BioMed research international IF: 02.300Volume 2026, Issue No.207Hypertension and Its Determinants Among White-Collar Workers: A Cross-Sectional Study Focusing on Lifestyle Risk Factors and Health Literacy白领工作者的高血压及其相关因素：一项聚焦生活方式风险因素与健康素养的横断面研究DOI: 10.1155/bmri/3545756 Npj biological timing and sleepVolume 3, Issue 1No.208Dual roles of circadian clock proteins in development and adult homeostasis昼夜节律蛋白在发育与成年稳态中的双重作用DOI: 10.1038/s44323-025-00061-1 Case reports in surgery IF: 00.500Volume 2026, Issue No.209Preoperative Glucagon-Like Peptide-1 Receptor Agonist Treatment to Allow Safe Laparoscopic Left Pancreatectomy in Extreme Obesity: The First Report术前胰高血糖素样肽-1受体激动剂治疗以允许在极端肥胖患者中安全实施腹腔镜左半胰腺切除术：病例报告DOI: 10.1155/cris/9201182 RSC medicinal chemistry IF: 03.600Ahead of Print.No.210Mitochondria-targeting symmetric diiminoguanidines: potent and selective anticancer agents against pancreatic tumors靶向线粒体的对称二亚氨基胍：强效且选择性的抗胰腺肿瘤药物DOI: 10.1039/d5md00808e Case reports in endocrinology IF: 00.900Volume 2026, Issue No.211Adrenal Crisis Induced by Zoledronic Acid in Two Patients With Hypopituitarism: A Case Report and Literature Review唑来膦酸诱发两名垂体功能减退患者肾上腺危象：病例报告与文献回顾DOI: 10.1155/crie/8854575 Pak J Med Sci IF: 01.700Volume 41, Issue 13PINS-NNO SupplNo.212Determinants of poor prognosis after surgery for glioblastoma: A retrospective analysis of predictors of morbidity and mortality in a low-middle income country胶质母细胞瘤术后预后不良的决定因素：基于低收入国家一项回顾性分析的发病率和死亡率预测指标DOI: 10.12669/pjms.41.13(PINS-NNOS).13364 F1000ResearchVolume 14, Issue No.213Global, regional and national estimates of coexisting forms of malnutrition among the neonates, infants and young children - A secondary data analysis of Demographic & Health Surveys (DHS) from 2006 to 2024新生儿、婴幼儿及低龄儿童中共患型营养不良的全球、区域及国家评估——基于2006年至2024年人口与健康调查（DHS）的二次数据分析DOI: 10.12688/f1000research.172154.1 Korean J Community NutrVolume 28, Issue 3No.214Mercury exposure is associated with obesity: a systematic review and meta-analysis汞暴露与肥胖相关：一项系统综述和Meta分析DOI: 10.5720/kjcn.2023.28.3.192 Nutrition and metabolic insights IF: 02.200Volume 19, Issue No.215Circulating Branched-Chain Amino Acids are Associated with Higher Odds of Obesity: Findings from the FiLWHEL Study循环支链氨基酸与较高的肥胖风险相关：FiLWHEL研究的结果DOI: 10.1177/11786388251395146 Nutrition and metabolic insights IF: 02.200Volume 19, Issue No.216Targeting CD44-Hyaluronic Acid Signalling in Obesity Treatment: Insights from Small Molecules and Nanobioconjugates靶向CD44-透明质酸信号通路治疗肥胖：基于小分子与纳米生物偶联物的见解DOI: 10.1177/11786388251408961 Hepatology communications IF: 04.600Volume 10, Issue 2No.217Name MASLD/MASH - and act on it命名MASLD/MASH并采取行动DOI: 10.1097/HC9.0000000000000897 Cancer medicine IF: 03.100Volume 15, Issue 1No.218Risk of Type II Diabetes Mellitus Among B-Cell Non-Hodgkin's Lymphoma SurvivorsB细胞非霍奇金淋巴瘤幸存者罹患2型糖尿病的风险DOI: 10.1002/cam4.71367 Endocrinology IF: 03.300Ahead of Print.No.219Targeting mineralocorticoid receptors to treat metabolic diseases via the adipocyte靶向盐皮质激素受体通过脂肪细胞治疗代谢性疾病DOI: 10.1210/endocr/bqag004 International wound journal IF: 02.500Volume 23internationalwoundjournal, Issue 1, Page e70808-e70813No.220A Novel Murine Model for Studying Impaired Wound Healing in Diabetes用于研究糖尿病受损伤口愈合的新型小鼠模型DOI: 10.1111/iwj.70826 Journal of cosmetic dermatology IF: 02.500Volume 25, Issue 1No.221Rising Public Interest in Weight Loss Medications and Growing Awareness of Their Aesthetic Sequelae: An Infodemiologic Google Trends Analysis and Clinical Diagnostic Patterning减肥药公众关注度上升及其美容后遗症认知增强：一项基于谷歌趋势的信息流行病学分析与临床诊断模式研究DOI: 10.1111/jocd.70670 MITAT : IF: 02.000Ahead of Print.No.222vNOTES versus laparoscopic chromopertubation for tubal factor and unexplained infertility: a comparative studyvNOTES与腹腔镜通染术治疗输卵管因素和不明原因不孕症的比较研究DOI: 10.1080/13645706.2026.2613118 The journal of sexual medicine IF: 03.300Volume 23, Issue 2No.223Health disparities among LGBTQ+ adults aged 33-35 in northern Finland: findings from the NFBC1986 cohort芬兰北部33-35岁LGBTQ+成人的健康差异：来自NFBC1986队列的研究发现DOI: 10.1093/jsxmed/qdaf366 Prim Health Care Res Dev IF: 01.700Volume 27, Issue No.224Developing a Weight Management and Metabolic Health Program to support patient-centred, effective, and efficient treatment for veterans with overweight or obesity: protocol for a quality improvement programme开发体重管理与代谢健康项目以支持超重或肥胖退伍军人的以患者为中心、有效且高效的治疗：一项质量改进项目方案DOI: 10.1017/S1463423625100650 Am J Case Rep IF: 01.000Volume 27, Issue No.225Long-Term Outcome of Isolated Duodenal Transit Bipartition as Initial Metabolic Surgery: A 19-Year Follow-Up Case Report孤立十二指肠转位分流术作为初始代谢手术的长期结局：一项19年随访病例报告DOI: 10.12659/AJCR.950650 J Clin Endocrinol Metab IF: 05.100Ahead of Print.No.226GH Response to Glucagon in Transition: Role of BMI and Etiology in Childhood-Onset GH Deficiency胰高血糖素刺激试验中GH反应在过渡期的评估：儿童期发病GH缺乏症中BMI与病因的作用DOI: 10.1210/clinem/dgaf674 Clinical endoscopy IF: 02.300Ahead of Print.No.227Impact of body mass index on the outcomes of endoscopic retrograde cholangiopancreatography: a systematic review and network meta-analysis体重指数对内镜下逆行胰胆管造影术预后的影响：一项系统评价与网络荟萃分析DOI: 10.5946/ce.2025.255 Obesity reviews IF: 07.400Ahead of Print.No.228Body Mass Index as a Prognostic Factor in Traumatic Brain Injury: Insights from a Real-World Cohort身体质量指数作为创伤性脑损伤的预后因素：来自真实世界队列的见解DOI: 10.1111/obr.70069 Case reports in ophthalmology IF: 00.600Volume 17, Issue 1No.229Successful Cataract Surgery in a Patient with a Port Delivery System Implant for Diabetic Macular Edema糖尿病黄斑水肿患者成功进行带眼内注射港植入物的白内障手术DOI: 10.1159/000548644 Int J Ophthalmol IF: 01.800Volume 19, Issue 1No.230Therapeutic approaches to diabetic macular edema assessed using optical coherence tomography and optical coherence tomography angiography使用光学相干断层扫描与光学相干断层扫描血管成像评估糖尿病黄斑水肿的治疗方法DOI: 10.18240/ijo.2026.01.20 J Curr Glaucoma PractVolume 19, Issue 4No.231Neovascularization of the Iris/Angle in Primary Angle Closure Glaucoma: A Distinct Entity!原发性闭角型青光眼中的虹膜/房角新生血管：一个独立的疾病实体！DOI: 10.5005/jp-journals-10078-1499 Taiwan journal of ophthalmology IF: 01.200Volume 15, Issue 4No.232Comment on optical coherence tomography and contrast sensitivity in early diabetic retinopathy评光学相干断层扫描与对比敏感度在早期糖尿病视网膜病变中的应用DOI: 10.4103/tjo.TJO-D-24-00127 Taiwan journal of ophthalmology IF: 01.200Volume 15, Issue 4No.233Effectiveness of aflibercept, ranibizumab, and Ozurdex for treating diabetic macular edema showing a suboptimal response: A comparative observational study阿柏西普、雷珠单抗与Ozurdex治疗贝伐珠单抗反应不佳的糖尿病黄斑水肿的疗效比较：一项观察性研究DOI: 10.4103/tjo.TJO-D-24-00122 Taiwan journal of ophthalmology IF: 01.200Volume 15, Issue 4No.234Clinical profile and associated risk factors of diabetic retinopathy at a tertiary eye center in Brunei Darussalam文莱达鲁萨兰国某三级眼科中心糖尿病视网膜病变的临床特征及相关危险因素DOI: 10.4103/tjo.TJO-D-24-00167 Taiwan journal of ophthalmology IF: 01.200Volume 15, Issue 4No.235Author's response to letter of editor for "Optical coherence tomography and contrast sensitivity in early diabetic retinopathy"作者对《糖尿病早期视网膜病变的光学相干断层扫描和对比敏感度》一文编辑来信的回复DOI: 10.4103/tjo.TJO-D-24-00128 PeerJ IF: 02.400Volume 14, Issue No.236An improved tortuosity measurement method combining curvature-based, breadth-first search and Euclidean distance for retinal image analysis结合基于曲率、广度优先搜索和欧氏距离的改进视网膜图像血管迂曲度测量方法DOI: 10.7717/peerj.20561 Digital health IF: 03.300Volume 12, Issue No.237Diabetic retinopathy detection and grading system using deep learning approach基于深度学习方法的糖尿病视网膜病变检测与分级系统DOI: 10.1177/20552076251410982 Quant Imaging Med Surg IF: 02.300Volume 16, Issue 1No.238Automated method for quantitative analysis of iris fluorescein angiography based on machine learning基于机器学习的虹膜荧光血管造影定量分析自动方法DOI: 10.21037/qims-2025-480 Malaysian family physicianVolume 20, Issue No.239Prevalence of postpartum glucose intolerance and its association with physical activity levels among women with prior gestational diabetes mellitus attending public primary care clinics in Penang: A cross-sectional study槟城妊娠期糖尿病史女性产后糖耐量异常患病率及其与体力活动水平的相关性：一项横断面研究DOI: 10.51866/oa.880 RC IF: 01.300Volume 26, Issue 12No.240Contemporary Percutaneous Coronary Intervention in Diabetic Patients当代糖尿病患者经皮冠状动脉介入治疗DOI: 10.31083/RCM44861 Circulation reports IF: 01.100Volume 8, Issue 1No.241Transient High-Glucose Exposure and Erk Signaling瞬时高糖暴露与Erk信号通路DOI: 10.1253/circrep.CR-25-0206 Curēus IF: 01.300Volume 17, Issue 12No.242Cardiac Arrest Secondary to Hypercapnia in an Obese Patient: A Case of Unresponsiveness With Preserved Awareness一例肥胖患者高碳酸血症继发心脏骤停：无反应状态伴意识保留的病例DOI: 10.7759/cureus.98800 World J Exp MedVolume 15, Issue 3No.243Triple probiotic combination effect on metabolic, oxidative stress, and inflammatory parameters in diabetic population: Systematic review and meta-analysis三重益生菌组合对糖尿病人群代谢、氧化应激及炎症参数的影响：系统综述与荟萃分析DOI: 10.5493/wjem.v15.i3.108467 Curēus IF: 01.300Volume 17, Issue 12No.244Prevalence and Predictors of Metabolic Syndrome in Women with Polycystic Ovarian Syndrome: A Cross-Sectional Study多囊卵巢综合征女性代谢综合征患病率及预测因素：一项横断面研究DOI: 10.7759/cureus.98869 JGH open : IF: 01.500Volume 10, Issue 1No.245Dietary Characteristics Associated With High Defecation Frequency and Constipation in Japanese Adults: A Cross-Sectional Study日本成年人中与高排便频率及便秘相关的饮食特征：一项横断面研究DOI: 10.1002/jgh3.70334 The Neurohospitalist IF: 00.900Ahead of Print.No.246Is Insulin Resistance Associated With Clinical Outcomes after Endovascular Treatment for Acute Stroke?胰岛素抵抗与急性卒中血管内治疗后临床结局相关DOI: 10.1177/19418744261416216 JCRPE IF: 01.500Ahead of Print.No.247The Potential Role of LRG1 in Hepatosteatosis and Insulin Resistance in Obese ChildrenLRG1在肥胖儿童肝脂肪变性与胰岛素抵抗中的潜在作用DOI: 10.4274/jcrpe.galenos.2026.2025-11-5 RC IF: 01.300Volume 26, Issue 12No.248Metabolic Remodeling and Mitochondrial Stress in Atrial Fibrillation: Mechanisms and Translational Targets心房颤动中的代谢重构与线粒体应激：机制与转化靶点DOI: 10.31083/RCM44688 Malaysian family physicianVolume 20, Issue No.249Vitamin B12 deficiency in metformin-treated community-dwelling older adults with diabetes: A cross-sectional multicentre study in Perak吡格列酮治疗的社区居住老年糖尿病患者维生素B12缺乏：马来西亚霹雳州的一项横断面多中心研究DOI: 10.51866/oa.718 HRB open researchVolume 8, Issue No.250Navigating Complexities In Randomized Trials: Insights From The EMERGE Trial Amidst Pandemic And Cybersecurity Threat在疫情与网络安全威胁中驾驭随机试验的复杂局面：来自EMERGE试验的启示DOI: 10.12688/hrbopenres.14233.1 J Gastrointest Oncol IF: 02.000Volume 16, Issue 6No.251Metformin reshapes the tumor microenvironment and enhances prognosis in invasive pancreatic ductal adenocarcinoma with diabetes mellitus二甲双胍重塑肿瘤微环境并改善伴糖尿病侵袭性胰腺导管腺癌的预后DOI: 10.21037/jgo-2025-457 RC IF: 01.300Volume 26, Issue 12No.252Left Atrial Reservoir Strain in Cardiovascular and Systemic Disease: Advances and Clinical Applications From Physiology to Practice左心房储器应变在心血管及系统性疾病中的应用：从生理学到临床实践的进展DOI: 10.31083/RCM46198 Curēus IF: 01.300Volume 17, Issue 12No.253Assessment of Prevalence and Risk Factors of Diabetes Distress Among Patients With Type 2 Diabetes Mellitus in an Urban Area of Chengalpattu District, India: A Cross-Sectional Study印度钦格尔普图地区城市2型糖尿病患者糖尿病困扰患病率及风险因素评估：一项横断面研究DOI: 10.7759/cureus.98974 J Pharm Bioallied Sci IF: 00.700Volume 17, Issue Suppl 4No.254Comparative Effect of SGLT2 Inhibitors and GLP-1 Agonists on Glycemic Control in Type 2 Diabetes MellitusSGLT2抑制剂与GLP-1激动剂对2型糖尿病患者血糖控制的比较效果DOI: 10.4103/jpbs.jpbs_1334_25 OTO open : IF: 01.500Volume 10, Issue 1No.255Thyroid Cancer Risk in Patients With Type 2 Diabetes Taking Glucagon-Like Peptide 1 Receptor Agonists使用胰高血糖素样肽-1受体激动剂的2型糖尿病患者甲状腺癌风险DOI: 10.1002/oto2.70188 Curēus IF: 01.300Volume 17, Issue 12No.256From Years of Pain to a Name: Fibromyalgia Uncovered从漫长疼痛到病名揭秘：纤维肌痛的诊断之旅DOI: 10.7759/cureus.98981 Health science reports IF: 02.100Volume 9, Issue 1No.257Weight-Reduction and Safety Profile of Once-Weekly Non-Comparable Biotherapeutic Subcutaneous Semaglutide Among People With Obesity: A Real-World Retrospective Study非可比生物治疗性皮下注射司美格鲁肽在肥胖人群中的减重效果与安全性特征：一项真实世界回顾性研究DOI: 10.1002/hsr2.71745 Curēus IF: 01.300Volume 17, Issue 12No.258Efficacy and Safety of Tirzepatide and Semaglutide for Obesity Management: A Real-World Comparison替尔泊肽与司美格鲁肽治疗肥胖的有效性和安全性：一项真实世界比较DOI: 10.7759/cureus.98858 Curēus IF: 01.300Volume 17, Issue 12No.259Blurring Fact and Fiction: A Complex Case of Recurrent Emergency Presentations, Polypharmacy, and Psychiatric Conflict事实与虚构的界限模糊：一例反复急诊、多重用药及精神科冲突的复杂病例DOI: 10.7759/cureus.98979 Alzheimer's & dementia IF: 06.800Volume 12, Issue 1No.260Baseline characteristics from evoke and evoke+: Two phase 3 randomized placebo-controlled trials of semaglutide in participants with early-stage symptomatic Alzheimer's diseaseevoke 与 evoke+ 试验的基线特征：两项在早期症状性阿尔茨海默病参与者中评估司美格鲁肽的3期随机安慰剂对照研究DOI: 10.1002/trc2.70200 194 Diabetes Mellitus(DM) 糖尿病 100 Obesity 肥胖症 67 Insulin 胰岛素 30 Type 2 diabetes mellitus(T2DM) 2型糖尿病 19 Diabetic Retinopathy 糖尿病视网膜病 16 Metabolic Syndrome 代谢综合征 13 Glucagon-Like Peptide-1 Receptor Agonists(GLP-1RA) 胰高血糖素样肽-1受体激动剂 9 Metformin 二甲双胍 7 Semaglutide 司美格鲁肽 5 Diabetic acidosis 糖尿病性酸中毒 5 Diabetic Kidney Disease(DKD) 糖尿病肾脏病 4 Diabetic Foot 糖尿病足 4 Empagliflozin 恩格列净 4 Gestational Diabetes Mellitus(GDM) 妊娠糖尿病 4 Hypoglycemic Agents 降糖药 3 Dipeptidyl-Peptidase IV Inhibitors(DPP-4i) 二肽基肽酶-4抑制剂 3 Sodium-Glucose Transporter 2 Inhibitors(SGLT-2i) 钠-葡萄糖协同转运蛋白2抑制剂 3 Diabetic Cardiomyopathies 糖尿病心肌病 3 gamma-Aminobutyric Acid(GABA) γ-氨基丁酸 3 Liraglutide 利拉鲁肽 2 Pregabalin 普瑞巴林 2 Canagliflozin 卡格列净 2 Tirzepatide 替尔泊肽 2 Vildagliptin 维格列汀 2 Sitagliptin 西他列汀 2 Linagliptin 利格列汀 1 Alogliptin 阿格列汀 1 Dulaglutide 度拉糖肽 1 Exenatide 艾塞那肽 1 Saxagliptin 沙格列汀 1 Teneligliptin 替格列汀 1 Bexagliflozin 贝沙格列净 1 Ertugliflozin 艾托格列净 1 Sotagliflozin 索格列净 1 Diabetes Complications 糖尿病并发症 1 Dapagliflozin 达格列净 1 Diabetic Peripheral Neuropathy(PDN) 糖尿病周围神经病变编辑：韩玉莲审校：韩玉莲

100 项与维格列汀相关的药物交易

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外链

KEGG	Wiki	ATC	Drug Bank
D07080	维格列汀	A10BH02	DB04876

研发状态

批准上市

10 条最早获批的记录,

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适应症	国家/地区	公司	日期
2型糖尿病	欧盟	Novartis Europharm Ltd.	2007-09-25
2型糖尿病	冰岛	Novartis Europharm Ltd.	2007-09-25
2型糖尿病	列支敦士登	Novartis Europharm Ltd.	2007-09-25
2型糖尿病	挪威	Novartis Europharm Ltd.	2007-09-25

未上市

10 条进展最快的记录,

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适应症	最高研发状态	国家/地区	公司	日期
1型糖尿病	临床3期	巴西	Novartis AG	2014-03-01
胰岛素抵抗	临床3期	英国	Novartis Pharmaceuticals Corp.	2010-05-01
微血管疾病	临床3期	英国	Novartis Pharmaceuticals Corp.	2010-05-01
低血糖	临床3期	瑞士	Novartis AG	2006-09-01
葡萄糖耐受不良	临床3期	美国	Novartis AG	2005-10-01
糖尿病前期	临床3期	美国	Novartis AG	2005-04-01
高血糖	临床3期	瑞士	Novartis Pharmaceuticals Canada, Inc.	2004-10-01
周围神经系统疾病	临床2期	法国	Novartis Pharmaceuticals Corp.	2010-10-01
糖尿病	临床2期	俄罗斯	Novartis Pharmaceuticals Canada, Inc.	2008-12-01

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临床结果

适应症

分期

评价

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研究	分期	人群特征	评价人数	分组	结果	评价	发布日期


ADA2024	N/A	2型糖尿病	-	Glimepiride 1mg/Vildagliptin 50mg/Metformin 500mg	糧憲鏇簾顧膚廠鹽憲壓(餘範製憲糧網齋廠夢蓋) = Three mild hypoglycemic events were reported with the starting dose 壓簾積夢觸範醖築選鹹 (艱壓窪願願鹽齋鬱糧壓 )	-	2024-06-14
				Glimepiride 2mg/Vildagliptin 50mg/Metformin 1000mg
NCT02999841 (Pubmed \| Diabetologia)	临床4期	2型糖尿病	-	Acarbose	顧鹹範積積觸製簾鏇蓋(壓齋蓋簾築簾遞鹹壓齋) = common reductions 選襯蓋糧壓製鑰鏇鏇膚 (廠簾鏇餘壓衊鹽衊艱築 )	-	2022-10-01
				Vildagliptin
NCT05359432 (Pubmed) 人工标引	临床4期	2型糖尿病	120	metformin+empagliflozin	築餘顧鏇簾夢鹽願艱艱(淵憲鬱鏇夢鬱鹹鬱窪鏇) = 醖構顧簾製壓襯簾範鏇獵選鹹醖獵積憲餘淵齋 (襯醖壓觸憲衊選製選觸, 0.68)	积极	2022-08-17
				metformin+vildagliptin	築餘顧鏇簾夢鹽願艱艱(淵憲鬱鏇夢鬱鹹鬱窪鏇) = 繭醖餘選鹹顧積鬱憲夢獵選鹹醖獵積憲餘淵齋 (襯醖壓觸憲衊選製選觸, 1.57)
ACTRN12618001907235 (Pubmed \| Front Endocrinol (Lausanne))	临床4期	高甘油三酯血症 \| 肥胖	346	Pioglitazone 30mg	齋築窪襯襯顧衊鏇願鏇(鹹遞願製築糧蓋簾夢蓋) = 範簾齋鹽壓窪觸壓鬱蓋蓋構觸鹽繭艱糧膚顧鏇 (觸憲網醖鹽鬱醖積衊鏇 )	-	2022-01-01
NCT03693560 (Pubmed \| Diabetes Res Clin Pract)	临床4期	冠心病 \| 糖尿病	80	Vildagliptin 50 mg/day	憲積鹽簾積範壓積廠蓋(壓廠繭壓窪衊衊願構壓) = 築鑰鹹壓蓋鹽遞觸夢窪壓鬱窪膚鏇醖糧餘製簾 (觸夢蓋齋淵齋願願選鹽 )	-	2020-12-01
				Glimepiride 4 mg/day	憲積鹽簾積範壓積廠蓋(壓廠繭壓窪衊衊願構壓) = 夢廠選膚網襯鑰鹽鬱觸壓鬱窪膚鏇醖糧餘製簾 (觸夢蓋齋淵齋願願選鹽 )
NCT01528254 (VERIFY study, EASD2020)	临床4期	2型糖尿病	2,001	Vildagliptin plus Metformin	遞憲鹹選齋鑰襯壓艱範(積觸餘壓餘艱壓衊壓構): adjusted mean change = 19.23 (95% CI, 8.42 ~ 30.03)	积极	2020-09-24
				Metformin
ACTRN12614001117606 (EASD2019)	临床4期	2型糖尿病 GLP-1	15	Vildagliptin 50 mg	獵憲範淵淵齋餘製顧顧(簾選膚壓鹹憲築衊艱廠) = 簾窪鹹遞遞糧夢願餘構壓願憲艱鑰鏇遞簾鑰憲 (觸窪廠製積鏇顧糧網鬱 )	积极	2019-09-19
				Placebo	獵憲範淵淵齋餘製顧顧(簾選膚壓鹹憲築衊艱廠) = 繭膚獵醖構範鬱齋齋範壓願憲艱鑰鏇遞簾鑰憲 (觸窪廠製積鏇顧糧網鬱 )
NCT02475070 (CTgov)	临床4期	2型糖尿病	28	Vildagliptin (Vildagliptin Treatment)	願積顧夢糧窪襯積糧餘(製構鹽齋鬱廠製構膚獵) = 願鹽鏇餘範艱襯網觸積簾觸範窪壓襯窪鬱積鹹 (襯廠鹽鬱齋艱鹽顧鑰夢, 2.6) 更多	-	2019-05-02
				Dapagliflozin (Dapagliflozin Treatment)	願積顧夢糧窪襯積糧餘(製構鹽齋鬱廠製構膚獵) = 鹹鏇製艱壓積齋廠簾襯簾觸範窪壓襯窪鬱積鹹 (襯廠鹽鬱齋艱鹽顧鑰夢, 2.7) 更多
NCT01703637 (Pubmed \| Endocr Connect)	N/A	糖尿病	300	Sitagliptin 100mg	顧壓簾膚鏇憲廠鬱製淵(糧襯網簾淵衊艱獵鹽選) = 積簾艱獵鹹鹹夢願簾淵糧壓醖淵鹹遞遞鏇蓋窪 (鹹築構襯鹹願壓膚鹽膚, -0.20 ~ -0.90)	-	2019-04-01
				Vildagliptin 50mg	顧壓簾膚鏇憲廠鬱製淵(糧襯網簾淵衊艱獵鹽選) = 獵獵壓餘鬱鹹製製鏇夢糧壓醖淵鹹遞遞鏇蓋窪 (鹹築構襯鹹願壓膚鹽膚, -0.40 ~ -1.40)
NCT00894868 (Pubmed \| JACC Heart Fail)	临床4期	2型糖尿病 \| 心脏衰竭	254	Vildagliptin 50 mg twice daily	製膚網鬱範夢願蓋蓋鹽(衊鑰範齋窪積網積淵鏇) = 糧製齋積顧簾衊繭窪築鬱鑰襯糧膚鹽築繭範鹽 (顧製窪製廠範鹹鹹願範 ) 更多	-	2018-01-01
				Placebo	製膚網鬱範夢願蓋蓋鹽(衊鑰範齋窪積網積淵鏇) = 獵獵鬱遞選範淵壓遞膚鬱鑰襯糧膚鹽築繭範鹽 (顧製窪製廠範鹹鹹願範 )