3月30日，上海美迪西生物医药股份有限公司与扬子江药业集团全资子公司上海海路生物技术有限公司正式举行战略合作签约仪式。双方将在新药临床前研发、项目出海与引进等领域开展深度协同，共同构建从源头创新到IND申报的高效、开放、国际化的研发新生态，引领中国生物医药产业的高质量发展与全球化进阶。
扬子江药业集团董事长特别助理兼集团药物研究院负责人王如伟、院长助理兼大分子创新中心负责人刘健、小分子创新中心负责人单文俊等，美迪西董事长兼CEO陈春麟、董事兼CBO蔡金娜、董事兼投融资副总裁陈国铠、临床前事业部执行副总裁葛健、运营副总裁刘彬彬等双方核心管理团队共同出席了签约仪式，并就合作愿景与实施路径进行了深入探讨。
海路生物 × 美迪西
优势互补，提速一站式新药研发
海路生物作为扬子江药业集团全资子公司与核心生物药研发平台，已建成从靶点发现、分子设计到临床前开发的完整大分子创新药研发体系。依托抗体发现与抗体工程平台，布局单/双抗、ADC、小核酸等前沿技术，聚焦肿瘤、代谢、自身免疫及中枢神经系统疾病，围绕临床未满足需求，构建领先技术体系，持续为患者提供更优治疗方案。
美迪西作为国内领先的一站式生物医药临床前研发服务CRO，服务覆盖药物发现、药学研究、临床前研究全过程，拥有符合NMPA、FDA、OECD GLP标准及AAALAC认证的研究体系，搭建了抗体、ADC、mRNA 疫苗、小核酸、PROTAC、CGT等新分子药物研发服务平台，积累了成熟的技术平台与成功案例，已助力多款创新药物实现出海。
16载合作，携手共进
合作筑基，从项目协同到战略共生
此次战略合作是双方长期协同、厚积薄发的必然结果。自2010年合作以来，美迪西与扬子江药业集团及海尼药业、海雁医药、海陵药业、海瑞药业、海路生物等多家子公司建立长期合作关系，服务覆盖临床前研发全链条，涉及小核酸、小分子化学药、中药等，赋能近百个项目研发，助力地佐辛注射液、奥美拉唑肠溶胶囊、左氧氟沙星滴眼液、替格瑞洛片、他克莫司等多款药物获批上市。
基于此，双方将以委托研发、FTE/FFS等灵活模式开展定制化研发协作，全面覆盖创新药的早期发现、体内外药效、CMC、药代、安全性评价及申报注册等一站式临床前服务，实现研发资源的高效整合与流程的无缝衔接。
引进来+走出去
双向赋能，构建创新药出海新生态
在商务拓展与合作方面，双方将共同构建一个“引进来+走出去”双向赋能、循环促进的新药出海生态，推动中国创新药融入全球市场。
助力出海：针对海路生物的创新药管线，美迪西将利用成熟的国际化平台与全球网络，积极链接海外合作伙伴，并通过策划参与全球顶级行业会议等方式，发布创新成果，加速管线海外授权与开发进程。
推动引进：美迪西将凭借国际视野与项目资源，为海路生物链接海外优质的创新管线与标的，促成在中国区域的开发与权益合作。
这一生态的构建，不仅旨在加速单个项目的国际化，更期望形成技术、资源与市场的可持续双向流动，提升中国创新药在全球的可见度与竞争力。
陈春麟
美迪西创始人、董事长&CEO
“
美迪西是国内领先的一站式生物医药临床前研发服务平台，技术平台完善、服务能力全面，尤其在新分子药物的临床前研究挑战中，拥有丰富且可验证的成功实践，是值得信赖的战略合作伙伴。期待双方能在更多前沿靶点探索、创新药物研发及全球化布局等方面持续深化协同，带来更多突破性疗法，共同为中国生物医药产业的高质量发展与技术升级注入强劲动能。
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王如伟
扬子江药业集团董事长特别助理兼集团药物研究院负责人
“
美迪西是国内领先的一站式生物医药临床前研发服务平台，技术平台完善、服务能力全面，尤其在新分子药物的临床前研究挑战中，拥有丰富且可验证的成功实践，是值得信赖的战略合作伙伴。期待双方能在更多前沿靶点探索、创新药物研发及全球化布局等方面持续深化协同，带来更多突破性疗法，共同为中国生物医药产业的高质量发展与技术升级注入强劲动能。
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关于扬子江药业集团
长江为魂，苍生为念，奔腾不息的扬子江，孕育滋养了以“求索进取，护佑众生”为使命的扬子江药业集团。
创建于1971年的扬子江药业集团，是科技部命名的全国首批创新型企业，总部位于江苏省泰州市，现有员工18000余人，旗下子公司分布泰州、北京、上海、南京、广州、成都、苏州、常州等地。主要产品中西药并举，拓展生物药、医疗器械、大健康业务，部分产品出口至全球40多个国家和地区。
坚守质量，扬子江永恒不变的生命线。集团践行“高质 惠民 创新 至善”的核心价值观，视患者如亲人，追求卓越品质，致力向社会提供优质高效的药品和健康服务。至今蝉联全国医药行业质量管理QC成果评比一等奖总数“二十连冠”，累计斩获31项国际质量管理小组会议（ICQCC）QC金奖；2次荣获“中国质量奖提名奖”，3次夺得中国品牌价值评价医药健康板块品牌价值、品牌强度“双第一”。2021年，荣获全球三大质量奖之一的EFQM全球奖（原“欧洲质量奖”）。2025年4月，获“EFQM全球奖”RbE现场评审七星认证。
创新驱动，扬子江奔腾不息的原动力。集团把创新作为高质量发展的战略基点，实施中药、化学药、生物药“三药并举”研发战略，加快培育医药健康新质生产力。建成4个国家级创新平台；拥有40个独家中药品种；2021年首个自主研发的1类化学创新药注射用磷酸左奥硝唑酯二钠获批上市；累计170多个仿制药品种通过或视同通过质量和疗效一致性评价。集团相继荣获3项国家科技进步二等奖；研究起草的5项中药材质量标准被录入《欧洲药典》。
责任同行，扬子江护佑众生勇担当。集团鼎力支持医学科技进步；第一时间驰援赈灾；发挥产业优势助力乡村全面振兴；热心体育公益事业，广泛支持健康促进；捐资设立三大慈善基金会……扬子江人在公益道路上向善而行。
“扬子江水哺育中华，扬子江药造福华夏”。奋进中的扬子江药业集团，与时代同频，与相关方携手同行，沿着高质量可持续发展之路，推动“药、医、养、食、游”融合发展，贡献全人类健康福祉，努力向“做中国领先、世界一流的医药健康产业集团”的愿景迈进。
关于海路生物
上海海路生物技术有限公司为扬子江药业集团全资子公司，作为集团核心生物药研发平台，建成从靶点发现、分子设计到临床前开发的完整大分子创新药研发体系。依托抗体发现与抗体工程平台，布局单/双抗、ADC、小核酸等前沿技术，聚焦肿瘤、代谢、自身免疫及中枢神经系统疾病，围绕临床未满足需求，构建领先技术体系，持续为患者提供更优治疗方案。
关于美迪西
美迪西（股票代码：688202.SH）成立于2004年，专注于为全球制药企业、研究机构及科研工作者提供全方位的临床前新药研发服务。公司构建了覆盖药物发现、药学研究至临床前研究的一站式综合研发平台，并在ADC、核酸、多肽、CGT、Protac、抗体等前沿领域搭建了服务平台。公司建立了符合国际规范的质量体系，已获得中国NMPA、美国FDA、欧盟OECD等GLP认证以及AAALAC国际认证。目前，公司在国内外拥有近8万平方米研发实验室。至2025年末，公司已为全球超2000家客户提供药物研发服务，参与研发完成的新药及仿制药项目已有610+件IND获批临床，携手国内外合作伙伴共同推动药物创新突破。美迪西将继续立足全球，聚力创新，为人类健康贡献力量！欢迎访问公司官网 www.medicilon.com.cn 了解更多详情。
Medicilon and Hailu Biotech of Yangtze River Pharmaceutical Group Forge Strategic Cooperation to Accelerate New Drug R&D and Global Outreach
On March 30, Medicilon held a strategic cooperation signing ceremony with Suzhou Hailu Biotech, a wholly-owned subsidiary of Yangtze River Pharmaceutical Group. The collaboration will focus on deepening synergy in preclinical new drug R&D, project introduction, and global market expansion, with the goal of jointly building an efficient, open, and international R&D ecosystem spanning from source innovation to IND filing. This partnership is poised to lead the high-quality development and global advancement of China’s biomedical industry.
Key executives from both organizations attended the ceremony and engaged in in-depth discussions on the cooperation’s vision and implementation roadmap. Representatives from Yangtze River Pharmaceutical Group included Ruwei Wang, Special Assistant to the Chairman and Head of the Group’s Pharmaceutical Research Institute; Jian Liu, Assistant to the Dean and Head of the Macromolecule Innovation Center; and Wenjun Shan, Head of the Small Molecule Innovation Center. From Medicilon, attendees included Chunlin Chen, Chairman and CEO; Jinna Cai, Director and Chief Business Officer; Guokai Chen, Director and Vice President of Investment & Financing; Jian Ge, Executive Vice President of the Preclinical Division; and Binbin Liu, Vice President of Operations.
Complementary Strengths to Accelerate One-Stop New Drug R&D
As a core biologic R&D platform and wholly-owned subsidiary of Yangtze River Pharmaceutical Group, Hailu Biotech has established a comprehensive macromolecule innovative drug R&D system covering target discovery, molecular design, and preclinical development. Leveraging its antibody discovery and engineering platforms, Hailu Biotech focuses on cutting-edge technologies such as monoclonal/bispecific antibodies, ADCs, and small nucleic acids, with a focus on oncology, metabolism, autoimmune diseases, and central nervous system disorders. The company is committed to addressing unmet clinical needs and delivering improved treatment options for patients through its leading technological capabilities.
Medicilon, a leading one-stop preclinical R&D CRO, offers end-to-end services spanning drug discovery, pharmaceutical research, and preclinical studies. The company operates a research system compliant with standards set by China’s NMPA, the U.S. FDA, OECD GLP, and AAALAC accreditation. Medicilon has also built specialized R&D service platforms for novel molecular drugs, including antibodies, ADCs, mRNA vaccines, small nucleic acids, PROTACs, and CGT. With a track record of mature technological platforms and successful cases, Medicilon has supported the global launch of multiple innovative drugs.
16 Years of Collaboration: From Project Partnership to Strategic Symbiosis
This strategic cooperation builds on a long-standing partnership between the two parties, which dates back to 2010. Over the past 16 years, Medicilon has established long-term cooperative relationships with Yangtze River Pharmaceutical Group and its subsidiaries, including Shanghai Haiyan Pharmaceutical Technology, Shanghai Hailu Biotechnology, Shanghai Haini Pharmaceutical, Nanjing Hailing Pharmaceutical, Guangzhou Hairui Pharmaceutical. Its services cover the entire preclinical R&D chain, encompassing small nucleic acids, small-molecule chemical drugs, and traditional Chinese medicines, empowering nearly 100 new drug R&D projects and supporting the approval and launch of key drugs such as Dezocine Injection, Omeprazole Enteric-coated Capsules, Levofloxacin Eye Drops, Ticagrelor Tablets, and Tacrolimus.
Shared R&D philosophies, aligned technical services, and consistent quality systems have fostered a mature and efficient collaboration mechanism between the two parties. This foundation of trust and business synergy has elevated their partnership from project-level cooperation to a strategic win-win alliance. Moving forward, the two parties will conduct customized R&D collaboration through flexible models such as commissioned R&D, FTE and FFS, covering one-stop preclinical services including early drug discovery, in vitro and in vivo efficacy studies, Chemistry, CMC, pharmacokinetics, safety evaluation, and regulatory registration. This integration will enable seamless process connection and efficient utilization of R&D resources.
"Bring In & Go Global": Building a Two-Way Ecosystem for Global Drug Outreach
In terms of business development, the two parties will jointly build a "bring in and go global" ecosystem to facilitate the integration of Chinese innovative drugs into the global market, featuring two-way empowerment and mutual promotion. To support global outreach, Medicilon will leverage its mature international platform and global network to connect Hailu Biotech with overseas partners, showcase innovative achievements through participation in top global industry conferences, and accelerate the overseas licensing and development of Hailu Biotech’s drug pipeline.
Meanwhile, Medicilon will use its international perspective and project resources to link Yangtze River Pharmaceutical Group with high-quality overseas innovative drug pipelines and targets, facilitating their development and equity cooperation in the Chinese market. Beyond accelerating the internationalization of individual projects, this ecosystem aims to create a sustainable two-way flow of technologies, resources, and markets, enhancing the global visibility and competitiveness of Chinese innovative drugs.
Chunlin Chen
Chairman and CEO of Medicilon
“
As the innovation engine of Yangtze River Pharmaceutical Group, Hailu Biotech has made forward-looking layouts in biologics, particularly in cutting-edge fields such as antibodies and small nucleic acids, demonstrating strong innovation potential. Medicilon will leverage its technological advantages and international project experience in novel molecular drug R&D—including antibodies, ADCs, PROTACs, and CGT—to provide Hailu Biotech with high-quality, efficient, one-stop R&D services, accelerating new drug development and global market entry.
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Ruwei Wang
Special Assistant to the Chairman and Head of Yangtze River Pharmaceutical Group’s Pharmaceutical Research Institute
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Medicilon is a leading one-stop preclinical R&D service platform in China, boasting a complete technological system and comprehensive service capabilities. It has rich, verifiable successful experience in addressing the challenges of preclinical research on novel molecular drugs, making it a trustworthy strategic partner. We look forward to deepening collaboration in cutting-edge target exploration, innovative drug R&D, and global layout, delivering more breakthrough therapies and jointly injecting strong momentum into the high-quality development and technological upgrading of China’s biomedical industry.
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