– Ribupatide (KAI-9531) aims to address critical need for greater weight loss, especially for people living with a BMI of 35 kg/m2 or greater – – KaiNETIC program includes three Phase 3 clinical trials in adults living with obesity or overweight – Jan. 12, 2026 -- Kailera Therapeutics, Inc., an advanced clinical-stage biotechnology company focused on elevating the next era of obesity care, today announced the randomization of the first participants in the KaiNETIC global Phase 3 clinical progr

First BGE-102 MAD cohort completed in obese individuals with elevated hsCRP receiving 120 mg QD; demonstrated rapid and profound reduction in inflammatory markers BGE-102 achieved 86% reduction in hsCRP at Day 14, with 93% of participants reaching normalized levels ( BGE-102 demonstrated significant reductions in IL-6, a key driver of systemic inflammation and cardiovascular risk, and fibrinogen, an independent predictor of cardiovascular events BGE-102 was well tolerated with a favorable safety

• Patient 1 of Cohort 1 has now completed the 24-month follow-up timepoint, and at month-24 post-treatment Patient 1 continued to demonstrate the powerful disease-modifying effects of BB-301, with deepening improvements in post-swallow residue and total dysphagic symptom burden as compared to the 12-month follow-up timepoint • Patient 4 of Cohort 1 continued to experience strong response to BB-301 at the 12-month follow-up timepoint • The first 4 patients enrolled into Cohort 1 have completed th

As part of the branding process, Polyrizon conducted comprehensive trademark screening across the U.S. and European markets Jan. 08, 2026 -- Polyrizon Ltd. Polyrizon Ltd. (Nasdaq: PLRZ) (“Polyrizon” or the “Company”), a pre-clinical-stage biotechnology company developing intranasal protective solutions, today announced that it has completed the branding process for its PL-14 allergy blocker, which will be marketed under the brand name NASARIX™. NASARIX™ is based on Polyrizon’s proprietary Cap

Database locks for studies on actinic keratosis (AK) and acne vulgaris achieved on January 5, 2026 Data generated will support key regulatory milestones for Ameluz PDT in both indications AK and acne are the two most commonly diagnosed skin disorders in the US1 Jan. 08, 2026 -- Biofrontera Inc. (Nasdaq: BFRI) (“Biofrontera” or the “Company”), a biopharmaceutical company specializing in the development and commercialization of photodynamic therapy (PDT), today announced the successful database

Jan. 08, 2026 -- Marius Pharmaceuticals, Inc. today announced the company will initiate a new post-marketing clinical study for potential label expansion evaluating KYZATREX® (testosterone undecanoate) CIII capsules in men ages 65–80 with hypogonadism. KYZATREX is a prescription drug used to treat adult men who have low or no testosterone levels due to certain medical conditions. As men age, the effects of low testosterone can intersect with broader age-related changes, influencing energy, mob

– Preferential MOP agonists such as oxycodone are often required for effective management of moderate to severe pain but come with significant risks of addiction and overdose – – With Dual NMR agonists, NOP and MOP agonism combine to provide analgesia while NOP counters many of the negative effects of MOP receptor agonism – – Dual NOP-MOP agonists have the potential to provide comparable analgesia, but with a substantially lower risk of abuse, addiction, and overdose than preferential MOP agonis

First-in-class condensate-modulating small molecule Development Candidate targeting pathogenic TDP-43 condensates. Restores global TDP-43 splicing function in disease-relevant systems. Demonstrates in vivo activity in multiple animal models with biomarker readouts supportive of disease modification. Potential applicability across TDP-43 proteinopathies including Traumatic Brain Injury and Frontotemporal Dementia. Jan. 08, 2026 -- Dewpoint Therapeutics, Inc., a clinical-stage biotechnology comp

InflaRx to prioritize izicopan as its leading pipeline asset, with a goal of continuing toward Phase 2b readiness in hidradenitis suppurativa (HS) To broaden signal-finding activities for izicopan in additional I&I (inflammation and immunology) indications, InflaRx intends to conduct a PK bridging study in China in 2026 to enable expedited proof of concept studies in China and additional geographies Toward the goal of fast-tracking izicopan development across all applicable I&I indications, Infl

NMRA-511 demonstrated a 15.7 reduction on mean CMAI total score, representing a clinically meaningful effect NMRA-511 demonstrated unsurpassed clinical effect size on CMAI total score in a pre-specified population with elevated anxiety NMRA-511 demonstrated a favorable tolerability and safety profile Neumora plans to evaluate higher doses of NMRA-511 via initiation of a multiple ascending dose expansion cohort in 2026 Company to host conference call today at 8:00 am ET Jan. 05, 2026 -- Neumora